DAXX Antikörper (His6)

Produktnummer ABIN238399

Dieser Maus Monoklonal Antikörper detektiert spezifisch DAXX in WB, IF und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DAXX Antikörper (His6) (ABIN238399)

Target: DAXX (Death-Domain Associated Protein (DAXX))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DAXX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: DAXX-03

Produktdetails anti-DAXX Antikörper

Bindungsspezifität: AA 580-740, His6

Spezifität: The antibody DAXX-03 reacts with C-terminal part of Daxx, a 110 kDa intracellular protein.

Produktmerkmale: Synonyms: BING2, DAP6, EAP1, Death domain-associated protein 6, Fas death domain-associatedprotein, ETS1-associated protein 1

Aufreinigung: Protein A affinity chromatography.

Immunogen: His6-tagged protein corresponding to amino acids 580-740 of human Daxx.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Western Blotting (2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu DAXX

Target: DAXX (Death-Domain Associated Protein (DAXX))

Andere Bezeichnung: DAXX

Hintergrund: Daxx is an apoptosis-modulating death-domain associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein

Gen-ID: 1616

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway