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Antikörper
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anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) Antikörper
ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) Antikörper
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| Synonyme |
Centd2, MGC176140, mKIAA0782, 2410002L19Rik, CENTD2, KIAA0782, ARAP1, centd2, Ci-ArfGAP-8 |
| Klonalität |
Monoklonal (ARAP1-2) |
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Wirt
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Reaktivität
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Applikation
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Alternativen Immunfluoreszenz (IF), Immunpräzipitation (IP), Western Blot (WB)
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| Produktnummer |
ABIN238383 |
| Menge |
0.1 mg (1.0 mg/ml) |
| Preis |
230,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PHdomain-containing protein 1
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Weitere Bezeichnung
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ARAP1 / CENTD2
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Swiss-Prot
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Q96P48
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Immunogen
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His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
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Kreuzreaktivität
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Human
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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ARAP1-2
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Beschreibung
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ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAPand RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptorseems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) andis important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to theplasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
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Spezifität
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The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein. Species: Human. Others not tested.
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Applikationshinweise
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Suitable for Western Blotting (2 μg/ml). Immunoprecipitation. Immunocytochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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1.0 mg/ml
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Reinigung
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Aff - Purified
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Buffer
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PBS, pH 7.4 with 15 mM sodium azide as preservative.
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1)", Typ "Antikörper" finden
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Wirte
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Ziege (5), Maus (4), Kaninchen (2)
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Reaktivitäten
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Human (9), Hund (1), Maus (1)
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Applikationen
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Western Blot (WB) (7), Immunpräzipitation (IP) (4), Enzyme Immunoassay (EIA) (2), Immunfluoreszenz (IF) (2), ELISA (1), ELISA (Detektionsantikörper) (1), Immunzytochemie (ICC) (1)
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