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ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) Antikörper

Antigen

ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1)

Synonyme Centd2, MGC176140, mKIAA0782, 2410002L19Rik, CENTD2, KIAA0782, ARAP1, centd2, Ci-ArfGAP-8
Klonalität Monoklonal (ARAP1-2)
Wirt
Reaktivität
Alternativen

Human

Applikation
Alternativen Immunfluoreszenz (IF), Immunpräzipitation (IP), Western Blot (WB)
Produktnummer ABIN238383
Menge 0.1 mg  (1.0 mg/ml)
Preis 230,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PHdomain-containing protein 1
Weitere Bezeichnung ARAP1 / CENTD2
Swiss-Prot Q96P48
Immunogen His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
Kreuzreaktivität Human
Isotyp IgG1  (Passende Sekundärantikörper)
Klon ARAP1-2
Beschreibung ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAPand RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptorseems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) andis important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to theplasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
Spezifität The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein. Species: Human. Others not tested.

Anwendungen

Applikationshinweise Suitable for Western Blotting (2 μg/ml). Immunoprecipitation. Immunocytochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 1.0 mg/ml
Reinigung Aff - Purified
Buffer PBS, pH 7.4 with 15 mM sodium azide as preservative.
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1)", Typ "Antikörper" finden
Wirte Ziege (5), Maus (4), Kaninchen (2)
Reaktivitäten Human (9), Hund (1), Maus (1)
Applikationen Western Blot (WB) (7), Immunpräzipitation (IP) (4), Enzyme Immunoassay (EIA) (2), Immunfluoreszenz (IF) (2), ELISA (1), ELISA (Detektionsantikörper) (1), Immunzytochemie (ICC) (1)