Mycobacterium Tuberculosis (CFP10) Antikörper

Antigen: Mycobacterium Tuberculosis (CFP10)

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Western Blot (WB)

Produktnummer: ABIN238347

Produktbeschreibung

Produktmerkmale: Synonyms: lhp, mtsA10, Rv3874, MT3988, MTV027.09, ESAT-6-like protein esxB, 10 kDa culture filtrateantigen cfp10, Secreted antigenic protein MTSA-10

Weitere Bezeichnung: Cfp10 / esxB

Gen-ID: 886194

Swiss-Prot: P0A566

Immunogen: CFP10 (Rv3874) of Mycobacterium tuberculosis

Beschreibung: CFP10 (10 kDa culture filtrate protein) is a low molecular weight protein isolated fromMycobacterium tuberculosis culture filtrates. CFP10 and the 6 kDa early secretory antigenof T cells (ESAT6) are secreted in abundance by Mycobacterium tuberculosis and arefrequently recognized by T cells from infected people. The genes encoding these proteinshave been deleted from the genome of the vaccine strain Bacille Calmette Guerin (BCG). CFP10 is one of a small number of secreted M. tuberculosis proteins now identified, thatappear to play key roles in tuberculosis pathogenesis and in the stimulation of immunity.

Spezifität: The polyclonal antibody reacts with CFP10 (LHP), a 12,3 kDa antigen encoded by geneRv3874 of Mycobacterium tuberculosis. The antibody recognizes CFP10 of Mycobacterium tuberculosis H37Rv and Mycobacteriumbovis, it reacts also with recombinant antigen produced in Escherichia coli.

Anwendungen

Applikationshinweise: Suitable for Western Blotting under Reducing conditions: 0.2-1 μg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0 mg/ml

Reinigung: Aff - Purified

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar