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Antikörper
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5) Antikörper
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5) Antikörper
| Antigen |
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| Synonyme |
CEA, CD66e, DKFZp781M2392, Psg30, 1600029H12Rik, CEACAM5, CEACAM |
| Klonalität |
Monoklonal (CB30) |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Durchflusszytometrie (FACS), Immunpräzipitation (IP), Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p))
Immunhistochemie (Paraffinschnitte) (IHC (p)) (51), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (49), Enzyme Immunoassay (EIA) (47), Western Blot (WB) (43), Durchflusszytometrie (FACS) (22), Immunpräzipitation (IP) (13), Immunfluoreszenz (IF) (9), Radioimmunoassay (RIA) (6), ELISA (5), ELISA (Detektionsantikörper) (3), Immunhistochemie (IHC) (3), Zell-ELISA (cELISA) (2), Dot Blot (Dot) (1)
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| Produktnummer |
ABIN192374 |
| Menge |
0.1 mg (1 mg/ml) |
| Preis |
180,00 € Zzgl. Versandkosten €40,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 3 bis 5 Werktagen |
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Weitere Bezeichnung
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CD66e
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Immunogen
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Human carcinoembryonic antigen (CEA, CEACAM5)
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Format
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Purified
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Isotyp
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IgG1
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Klon
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CB30
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Beschreibung
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The CD66e (CEA, 180-200 kDa) is a member of carcinoembryonic antigens,immunoglobulin supergene family and consists of a single N domain (structural homology tothe immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and Bdomains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capableof both homophilic and heterophilic adhesion.Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells.CD66e is found in serum and it is clinically used as a tumor marker for early detection ofdisease due to its expression in adenocarcinomas - potential target of tumor imaging anddrug targeting.
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Spezifität
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The antibody CB30 recognizes CD66e (CEA, 180-200 kDa), a cell surface boundcarcinoembryonic antigen mainly expressed on epithelial cells.
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Applikationshinweise
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Immunohistochemistry (paraffin sections) - Staining technique: Standard ABC technique (DAB+)Recommended dilution: 10 µg/ml (1: 100) Positive tissue: Adenocarcinoma of colon. Pretreatment: 0,1% pepsin in 0,1 M HCl for 30 min at room temperature
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Konzentration
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1 mg/ml
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Reinheit
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> 95% (by SDS-PAGE)
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Reinigung
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Purified from hybridoma culture supernatant by protein-A affinity chromatography.
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Lagerung
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Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
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Forschungsgebiet
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CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5)", Typ "Antikörper" finden
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Wirte
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Maus (96), Kaninchen (21), Ziege (3), Huhn (1)
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Reaktivitäten
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Human (112), Maus (1)
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Applikationen
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Immunhistochemie (Paraffinschnitte) (IHC (p)) (51), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (49), Enzyme Immunoassay (EIA) (47), Western Blot (WB) (43), Durchflusszytometrie (FACS) (22), Immunpräzipitation (IP) (13), Immunfluoreszenz (IF) (9), Radioimmunoassay (RIA) (6), ELISA (5), ELISA (Detektionsantikörper) (3), Immunhistochemie (IHC) (3), Zell-ELISA (cELISA) (2), Dot Blot (Dot) (1)
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Konjugate
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FITC (5), HRP (1)
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Epitope
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Group I (4), AA 19-217 (1), Center (1), Group IV (1), Group IVa or II (1)
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