Der FITC-konjugierte Maus Monoklonal anti-CD235ab Antikörper (Klon HIR2) (ABIN192327) detektiert spezifisch CD235ab in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Kurzübersicht für CD235ab Antikörper (N-Term) (FITC) (ABIN192327)
Target
CD235ab (CD235a + CD235b)
(Glycophorin A + B (CD235a + CD235b))
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
Dieser CD235ab Antikörper ist konjugiert mit FITC
Applikation
Flow Cytometry (FACS)
Klon
HIR2
Bindungsspezifität
N-Term
Verwendungszweck
Anti-Hu CD235ab FITC
Kreuzreaktivität (Details)
Human
Produktmerkmale
The mouse monoclonal antibody HIR2 recognizes an epitope within the N-terminal (extracellular) portion of CD235a (glycophorin A) and CD235b (glycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells.
Aufreinigung
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze,Protect from prolonged exposure to light
Lagerung
4 °C
Informationen zur Lagerung
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Target
CD235ab (CD235a + CD235b)
(Glycophorin A + B (CD235a + CD235b))
Andere Bezeichnung
CD235ab
Hintergrund
CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A/B, GYPA/B, GPA/B, PAS-2/3, Sialoglycoprotein alpha/beta, GPSAT, GPErik, MSN blood group