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Substance P Antikörper

Antigen

Substance P

Synonyme NK2, NPK, NKNA, TAC2, Hs.2563, SP, NK1, NK-1, Nkna, PPT-A, MGC151458, 4930528L02Rik
Klonalität Monoklonal (SP-DE4-21)
Wirt
Reaktivität
Alternativen

Meerschweinchen

Applikation
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Immunfluoreszenz (IF)
Produktnummer ABIN192028
Menge 100 µg  (Varianten)
Preis 330,00 €   Zzgl. Versandkosten €40,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: Substance-P
Gen-ID 6863
Swiss-Prot P20366
Immunogen Synthetic human Substance P. AA Sequence: R-P-R-P-Q-Q-F-F-G-L-M
Kreuzreaktivität Meerschweinchen, Human, Maus, Ratte (Rattus)
Isotyp IgG1  (Passende Sekundärantikörper)
Klon SP-DE4-21
Beschreibung Substance P (SP) is currently thought to be one of the most important neurotransmittersand neurotransmitters in the brain. It is an undecapeptide belonging to the tachykininfamily, which consists of excitatory neuropeptides synthesised in neuronal and glial cellsof the human central and peripheral nervous system. Substance P, Neurokinin A,Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavageof the precursor Protachykinin-1. Substance P forms the major endogenous ligand forNeurokinin 1 Receptor. The pharmacology of Substance P has been associated with anumber of neurological and psychiatric disorders, namely nociception, migraine, asthma,nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. Ithas also been linked to obesity.
Spezifität The antibody reacts specifically with Substance P. No cross reaction against related Tachykinins (Neurokinin A, Neurokinin B, and Kassinin). Species: Human. Others not tested. Add. Information: LocusID 6863 (tachykinin precursor contains: substance K, substance P, neurokinin 1,neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)

Anwendungen

Applikationshinweise ELISA (1/10.000)Immunostaining (1/1000)Immunostaining of Rat Tissue (1/2000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Reinigung Purified
Buffer 0.1 M Glycin PBS pH 7,4Reconstitution: Restore in aqua bidest to 1 mg/ml.
Lagerung Store the antibody lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Forschungsgebiet Neurologie, Zell-/Gewebemarker
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Substance P", Typ "Antikörper" finden
Wirte Kaninchen (39), Maus (8), Meerschweinchen (4), Ratte (3)
Reaktivitäten Human (39), Ratte (Rattus) (25), Maus (21), Rind (Kuh) (16), Meerschweinchen (16), Kaninchen (16), Pferd (15), Schaf (15), Säugetiere (2), Huhn (1), Fisch (1), Affe (1), Schwein (1)
Applikationen Immunfluoreszenz (IF) (31), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Durchflusszytometrie (FACS) (19), Immunhistochemie (Paraffinschnitte) (IHC (p)) (17), ELISA (8), Immunhistochemie (IHC) (8), Western Blot (WB) (4), Enzyme Immunoassay (EIA) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Radioimmunoassay (RIA) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope AA 4-11 (2)