Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper

Antigen: Cholinergic Receptor, Muscarinic 1 (CHRM1)

Synonyme: M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN185701

Produktbeschreibung

Weitere Bezeichnung: M1 mAChR / CHRM1

Gen-ID: 1128, 12669 (mouse), 25229 (rat)

Immunogen: C-DKRRWRKIPKRPGSVH

Format: Affinity-purified

Beschreibung: All names and symbols: CHRM1, M1 mAChR, cholinergic receptor, muscarinic 1 , HM1, M1, MGC30125 , muscarinic acetylcholine receptor M1. Official Symbol: CHRM1. RefSeq number(s): NP_000729.2

Spezifität: Human, Mouse, Rat, Dog 460 aa

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 48kDa band observed in Human Brain lysates (calculated MW of 51.4kDa according to NP_000729.2). Recommended concentration: 1-3µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN185701 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publikationen

Publikationen: Caccamo, Oddo, Billings et al.: "M1 receptors play a central role in modulating AD-like pathology in transgenic mice." in: Neuron, Vol. 49, Issue 5, pp. 671-82, 2006 (PubMed).