PRKRA Antikörper (Middle Region)

Produktnummer ABIN183963

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-PRKRA Antikörper (ABIN183963) detektiert spezifisch PRKRA in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen und Pferd.

Kurzübersicht für PRKRA Antikörper (Middle Region) (ABIN183963)

Target: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PRKRA Antikörper

Bindungsspezifität: Middle Region

Sequenz: RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA KRNAAEKFLA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRKRA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRKRA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 313 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PRKRA Antikörper (ABIN183963)

Yoshida, Okamura, Hoshino, Shono, Yoshioka, Hinode, Yoshida: "Interaction between PKR and PACT mediated by LPS-inducible NF-?B in human gingival cells." in: Journal of cellular biochemistry, Vol. 113, Issue 1, pp. 165-73, (2011) (PubMed).

Details zu PRKRA

Target: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Andere Bezeichnung: PRKRA

Hintergrund: PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA).
Alias Symbols: RAX, PACT, DYT16, HSD14
Protein Interaction Partner: ZMAT3, PRKRA, TARBP2, LYAR, STAU1, UBC, H1F0, EIF2AK2, CCDC124, C1orf35, DDX50, NOC3L, NOP16, STAU2, ZNF346, GTPBP4, DICER1, RBM34, EBNA1BP2, IFRD2, TCOF1, BMI1, SRPK3, POLR2G, MDC1, CAND1, UBE2I, SIRT7, ZFP28, KIAA1377, NKRF, SNX5, RABEPK, CEBPZ, SHC1, Z
Protein Size: 313

Molekulargewicht: 34 kDa

Gen-ID: 8575

NCBI Accession: NM_003690, NP_003681

UniProt: O75569

Pathways: Regulatorische RNA Pathways