DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) Antikörper

Antigen: DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23)

Synonyme: prp28, PRPF28, MGC8416, U5-100K, U5-100KD

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Rind (Kuh), Hund, Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN183337

Produktbeschreibung

Weitere Bezeichnung: DEAD box protein 23

Beschreibung: DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex, it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. Keywords: DDX23, DEAD (Asp-Glu-Ala-Asp) box polypeptide 23, ARP36376_T100, NP_004809, NM_004818, Q9BUQ8, HGNC:17347, MGC8416, U5-100K, prp28

Anwendungen

Applikationshinweise: ELISA titre: 1:1562500 . Western Blotting: Suggested dilution at 1.25 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) antibody

Publikationen

Publikationen: Teigelkamp, Mundt, Achsel et al.: "The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p." in: RNA (New York, N.Y.), Vol. 3, Issue 11, pp. 1313-26, 1998 (PubMed).