HEY1 Antikörper (C-Term)

Produktnummer ABIN182593

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HEY1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für HEY1 Antikörper (C-Term) (ABIN182593)

Target: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEY1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HEY1 Antikörper

Bindungsspezifität: C-Term

Sequenz: PQNGHGNAGT TASPTEPHHQ GRLGSAHPEA PALRAPPSGS FGPVLPVVTS

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HEY1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HEY1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 304 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HEY1 Antikörper (ABIN182593)

Zhang, Weimann, Stolzenburg, Neuhaus, Berndt-Paetz: "Notch2/3-DLL4 interaction in urothelial cancer cell lines supports a tumorigenic role of Notch signaling pathways in bladder carcinoma." in: PloS one, Vol. 20, Issue 2, pp. e0317709, (2025) (PubMed).

Details zu HEY1

Target: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Andere Bezeichnung: HEY1

Hintergrund: Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates.
Alias Symbols: CHF2, OAF1, HERP2, HESR1, HRT-1, BHLHb31
Protein Interaction Partner: SYVN1, DERL2, HEY2, SEL1L, PRKD2, LAPTM5, SKIL, SMAD9, SMAD3, ARNT, NOTCH1, ELAVL1, FBXW7, HEY1, GATA1, MYOD1,
Protein Size: 304

Molekulargewicht: 33 kDa

Gen-ID: 23462

NCBI Accession: NM_012258, NP_036390

UniProt: Q9Y5J3

Pathways: Tube Formation