SLC5A2 Antikörper (N-Term)
Kurzübersicht für SLC5A2 Antikörper (N-Term) (ABIN155150)
Target
Alle SLC5A2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- This antibody detects 74 kDa SGLT-2. A ~50-60 kDa band can also be detected, presumably represents the SGLT-2 cleavage fragments.
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Aufreinigung
- Affinity Chromatography on Protein A .
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Immunogen
- Synthetic peptide near the N-terminus of Mouse SGLT-2
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Applikationshinweise
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Western blotting (0.5-4 μg/mL). Jurkat cell lysate, mouse small intestine tissue lysate and rat kidney can be used asPositive Controls.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.2 mg/mL
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Buffer
- Phosphate-buffered saline (PBS) containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid Repeated freeze/defrost cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody at -20 °C. For long term storage aliquot and store at -70 °C.
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- SLC5A2 (Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 2 (SLC5A2))
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Andere Bezeichnung
- SGLT2 / SLC5A2
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Hintergrund
- Sodium glucose co transporters (SGLTs) are located in the brush-border membrane, but transported out of the cell across the basolateral membranes by a facilitated sugar transporter (GLUT). At least three members of SGLTs (SGLT 1-3) have been cloned and characterized. SGLTs transport a methyl-D-glucoside (a-MDG), a non-metabolized model substrate, in Na-dependent manner. SGLT-1 does not discriminate a-MDG, glucose, and galactose. SGLT2/3 do not transport D-galactose efficiently.Synonyms: Low affinity sodium-glucose cotransporter, Na(+)/glucose cotransporter 2, Sodium/glucose cotransporter 2, Solute carrier family 5 member 2
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Gen-ID
- 6524
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NCBI Accession
- NP_003032
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UniProt
- P31639
Target
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