AP3D1 Antikörper (AA 675-700)

Produktnummer ABIN129555

Hersteller Produkt- Nr.: 600-101-290

Zitiert in 2+ Publikationen. Der Ziege Polyklonal anti-AP3D1 Antikörper (ABIN129555) detektiert spezifisch AP3D1 in WB, ELISA und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AP3D1 Antikörper (AA 675-700) (ABIN129555)

Target: AP3D1 (Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser AP3D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Produktdetails anti-AP3D1 Antikörper

Bindungsspezifität: AA 675-700

Hersteller Produkt- Nr.: 600-101-290

Hersteller: Rockland

Verwendungszweck: AP3D1 Antibody

Kreuzreaktivität (Details): This affinity purified antibody is directed against human AP3D1.

Produktmerkmale: Synonyms: goat anti-AP3D1 antibody, AP-3 complex subunit delta-1, Adapter-related protein complex 3 subunit delta-1, AP-3 complex subunit delta, Delta-adaptin

Aufreinigung: The product was affinity purified from antiserum by immunoaffinity purification.

Sterilität: Sterile filtered

Immunogen:

Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 675-700 of Human AP3D1.

Immunogen Type: Conjugated Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 130 kDa in size corresponding to AP3D1 by western blotting in the appropriate cell lysate or extract. Multiple isoforms exist for this protein.

Western Blot Dilution: 1:500 - 1:2,000

Immunoprecipitation Dilution: 1:100

ELISA Dilution: 1:5,000 - 1:20,000

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.6 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Referenzen für anti-AP3D1 Antikörper (ABIN129555)

Zheng, Saunders, Sorensen, Waxmonsky, Conner: "Notch signaling from the endosome requires a conserved dileucine motif." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 297-307, (2013) (PubMed).

Concepcion, Flores-Garcuia, Hamilton: "Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing." in: PLoS genetics, Vol. 5, Issue 5, pp. e1000484, (2009) (PubMed).

Details zu AP3D1

Target: AP3D1 (Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))

Andere Bezeichnung: AP3D1

Hintergrund: Background: AP3D1 (also known as Delta-adaptin 3, AP-3 complex delta subunit and Delta-adaptin) is a subunit of the AP3 adaptor-like complex, which is not associated with clathrin. The AP3D1 subunit is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.

Gen-ID: 8943, 117553580

UniProt: O14617