SMAD7 Antikörper

Produktnummer ABIN127302

Der Kaninchen Polyklonal anti-SMAD7 Antikörper (ABIN127302) detektiert spezifisch SMAD7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SMAD7 Antikörper (ABIN127302)

Target: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMAD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMAD7 Antikörper

Spezifität: This antibody reacts to Smad7.

Aufreinigung: Affinity purified

Immunogen: Synthetic peptide from human Smad 7.

Anwendungsinformationen

Applikationshinweise: Western blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu SMAD7

Target: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Andere Bezeichnung: SMAD7

Hintergrund: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.Synonyms: MAD homolog 7, MAD homolog 8, MADH7, MADH8, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 7, SMAD 7, SMAD family member 7, SMAD-7

Gen-ID: 4092

NCBI Accession: NP_001177750

UniProt: O15105

Pathways: Interferon-gamma Pathway, Cell-Cell Junction Organization