VDAC1 Antikörper (C-Term)

Produktnummer ABIN127225

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VDAC1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Kaninchen, Rind (Kuh) und Schwein.

Kurzübersicht für VDAC1 Antikörper (C-Term) (ABIN127225)

Target: VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VDAC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VDAC1 Antikörper

Bindungsspezifität: C-Term

Spezifität: The antibody recognizes ~31 kDa VDAC/Porin.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide corresponding to the C-terminus of Human VDAC

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu VDAC1

Target: VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

Andere Bezeichnung: VDAC1

Hintergrund: The Voltage-Dependent Anion Channel (VDAC or mitochondrial Porin)I is an outer membrane mitochondrial protein. The VDAC protein is thought to form the major pores through which adenine nucleotides are transferred through the outer mitochondrial membrane. VDAC has also been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, ANT, and CypD is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis.Synonyms: Mitochondria marker, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC, Voltage-dependent anion-selective channel protein 1

Gen-ID: 7416

NCBI Accession: NP_003365

UniProt: P21796