GNAI2 Antikörper
Kurzübersicht für GNAI2 Antikörper (ABIN127055)
Target
Alle GNAI2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The antibody detects human Gαi2. It also cross-reacts with Gαi3 and partially with Gαi1.
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Aufreinigung
- Affinity chromatography
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anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 1-355) antibody
GNAI2 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 3G11 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 1-355) antibodyGNAI2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 1-339) antibodyGNAI2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2E4 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 289-299) antibodyVerified GNAI2 Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (Center) antibodyGNAI2 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 25GB410 unconjugated Recombinant Antibody
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Western blot (0.5-1 μg/mL). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid Repeated freeze/defrost cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. For long term storage, aliquot and freeze at -70 °C.
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- GNAI2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2))
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Hintergrund
- Gαi2 is a 40-41 kDa alpha-subunit of heterotrimeric protein, that shares sequence homology with Gαi3 and Gαi1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gαi2 is expressed widely in tissues and cell lines. Activation of PLC-β by Gαi-coupled receptors is the result of release of Gβγ subunits from Gαi. Gαi2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.Synonyms: Adenylate cyclase-inhibiting G alpha protein, GNAI2, GNAI2B, Guanine nucleotide-binding protein G(i), alpha-2 subunit
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Gen-ID
- 2771
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NCBI Accession
- NP_002061
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UniProt
- P04899
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Pathways
- cAMP Metabolic Process, G-protein mediated Events, Thromboxane A2 Receptor Signaling
Target
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