GPR3 Antikörper

Produktnummer ABIN122137

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GPR3 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GPR3 Antikörper (ABIN122137)

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GPR3 Antikörper

Spezifität: Reacts with G Protein-Coupled Receptor GPR3 (family: GPCR, subfamily: Lysophospholipid/Lysosphingolipid)

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 6 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GPR3

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Andere Bezeichnung: GPR3 / ACCA

Hintergrund: GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging. GPR3 has been reported at low abundance predominantly in the central nervous system and in the lung and kidney. ESTs have been isolated from brain and colon libraries.Synonyms: ACCA orphan receptor, G-protein coupled receptor 3

Gen-ID: 2827

UniProt: P46089

Pathways: cAMP Metabolic Process