MHC Class II I-Ab Antikörper

Antigen: MHC Class II I-Ab

Klonalität: Monoklonal (25-5-16S)

Wirt: Maus

Reaktivität: Maus

Applikation: Zytotoxizitätstest (CyTox), Durchflusszytometrie (FACS)

Produktnummer: ABIN118320

Produktbeschreibung

Isotyp: IgM  (Passende Sekundärantikörper)

Klon: 25-5-16S

Beschreibung: Class II antigens are most highly expressed on antigen-presenting cells including B cells, macrophages, dendritic cells and certain epithelial cells.

Spezifität: This antibody specifically reacts with the I-Ab encoded MHC class II antigen expressed on mouse strains of the H-2b haplotype.

Anwendungen

Applikationshinweise: Flow cytometry: see protocol. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 0.2 mg/ml

Buffer: PBS and 0.09% NaN3

Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Forschungsgebiet: Haupthistokompatibilitätskomplex (MHC), Immunologie

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Klein, Figueroa, David: "H-2 haplotypes, genes and antigens: second listing. II. The H-2 complex." in: Immunogenetics, Vol. 17, Issue 6, pp. 553-96, 1983 (PubMed).

Ozato, Sachs: "Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 126, Issue 1, pp. 317-21, 1981 (PubMed).