MSTN Antikörper

Produktnummer ABIN115510

Produktdetails anti-MSTN Antikörper

Target: MSTN (Myostatin (MSTN))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser MSTN Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Sequenz: Total 248 AA. MW: 28 kDa (calculated ). 243 AA of recombinan t human Myostatin Propeptide and 5 extra AA: MGNENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRRKLN Remarks: The amino acid sequence of the recombinan t Human Myostatin Propeptide is 100% homologous with the amino acid sequence of the Human Myostatin Propeptide without signaling sequence.

Spezifität: The recombinant human myostatin propeptide is 100 % homologous with the human serum myostatin propeptide.

Aufreinigung: Immunoaffinity chromatography.

Immunogen: Recombinant human myostatin propeptide from E. coli.

Anwendungsinformationen

Applikationshinweise: Suitable for ELISA: Titer is defined by indirect ELISA, it is: > 1/100,000 for antibodyconcentration 1 mg/mL, 25 ng of antigen are coated per well, and is then defined at a pointof maximal decrease of the titration curve.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 0.05 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.

Konzentration: 1.0 mg/mL

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2 containing no preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing. Dilute only prior to immediate use.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20° C or below.

Details zu MSTN

Target: MSTN (Myostatin (MSTN))

Andere Bezeichnung: Myostatin (MSTN Produkte)

Synonyme: GDF-8 antikoerper, GDF8 antikoerper, gdf8 antikoerper, mstn antikoerper, zgc:109749 antikoerper, Gdf8 antikoerper, NV13143 antikoerper, MSLHP antikoerper, Cmpt antikoerper, myostatin antikoerper, myostatin b antikoerper, growth/differentiation factor 8 antikoerper, MSTN antikoerper, mstnb antikoerper, LOC5577632 antikoerper, BRAFLDRAFT_290840 antikoerper, Mstn antikoerper, mstn antikoerper

Hintergrund: Myostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70 % ) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.Synonyms: GDF-8, GDF8, Growth differentiation factor 8, MSTN

Gen-ID: 2660

NCBI Accession: NP_005250

UniProt: O14793