EpCAM Antikörper

Produktnummer ABIN114701

Der Maus Monoklonal anti-EpCAM Antikörper wird verwendet zum Nachweis von EpCAM in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für EpCAM Antikörper (ABIN114701)

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EpCAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: MK-1-25

Produktdetails anti-EpCAM Antikörper

Spezifität: The anti human EPCAM antibody, clone MK-1-25 is a mouse monoclonal antibody against recombinant human EPCAM.

Aufreinigung: Purified

Immunogen: Recombinant human EPCAM produced in E.coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.1 mL of deionized water

Konzentration: 1.0 mg/mL

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE

Konservierungsmittel: Azide free

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one month. For longer storage, aliquot and freeze unused portion at -20 °C in volumes appropriate for single usage. Avoid freeze/thaw cycles.

Details zu EpCAM

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Andere Bezeichnung: CD326 / EPCAM / TACSTD1

Hintergrund: The Ep-CAM antigen (Epithelial Cell Adhesion Molecule), also termed as MK-1, GA733-2, KSA, 17-1A or EGP40, is a 40 kDa type-I transmembrane glycoprotein with properties of Ca2+ -independent homotypic intracellular adhesion molecule. The full leghth of the molecule is 314 amino acids. Structurally, Ep-CAM is not related to any of the major families of adhesion molecules. The Ep-CAM antigen is overexpessed on the majority of tumor cells of most human epithelia of variety of tumor tissues such as stomach, colon, pancreas, gall bladder, bile duct, mammary gland, breast and lung carcinoma. Ep-CAM has been suggested to be involved in the differentiation and growth of epithelial cells under normal physiological conditions through its homotypic cell-cell adhesion activity. As it is overexpressed on most carcinomas, Ep-CAM antigen has been used as a target for diagnosis and therapy of cancer.Synonyms: Adenocarcinoma-associated antigen, EGP314, Ep-CAM, Epithelial cell adhesion molecule, Epithelial glycoprotein 314, GA733-2, KS 1/4 antigen, KSA, M1S2, M4S1, MIC18, Major gastrointestinal tumor-associated protein GA733-2, TROP1, Trop-1, Tumor-associated calcium signal transducer 1

Gen-ID: 4072

NCBI Accession: NP_002345

UniProt: P16422