G Protein alpha 0 (AA 345-354) Antikörper

Antigen: G Protein alpha 0

Epitope: AA 345-354

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN114078

Produktbeschreibung

Produktmerkmale: Synonyms: Gnao1, Gna0, Gnao, Guanine nucleotide-binding protein G(o) subunit alpha

Weitere Bezeichnung: G protein alpha 0 (345-354)

Gen-ID: 14681

Swiss-Prot: P18872

Immunogen: Synthetic peptide corresponding to the amino acids 345 - 354 of the native moleculeconjugated to Keyhole Limpet HaemocyaninAA Sequence: {C-}A-N-N-L-R-G-C-G-L-Y

Beschreibung: GTP binding proteins (G proteins) play a critical role in signal transduction by couplingreceptors to effectors. The intracellular consequences of G protein activation includesecond messenger generation, protein phosphorylation, ion channel activation, geneinduction, cell growth, and differentiation. Go belongs to the pertussis toxin sensitive Gproteins. It consists of two subtypes of a subunits (ao1 and ao2) derived from alternativesplicing of a single gene. ao1 differs from ao2 within the C terminal.

Spezifität: This antibody detects G Protein-alpha 0. Species: Mouse. Others not tested.

Anwendungen

Applikationshinweise: ELISA (1/100K - 1/400K). Western blot (gives a band at 39 kDa when used under reducing conditions against ratbrain). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 2.4 mg/ml (lot spec.)

Buffer: PBS , pH 7.2, 0.09 % Sodium Azide

Lagerung: Store the antibody at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar