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KRT20 Antikörper (FITC)

KRT20 Reaktivität: Human, Ratte, Schwein IHC (p), IF, IHC (fro), FACS Wirt: Maus Monoclonal KS20-10 FITC
Produktnummer ABIN111170
  • Target Alle KRT20 Antikörper anzeigen
    KRT20 (Keratin 20 (KRT20))
    Reaktivität
    • 91
    • 29
    • 27
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Schwein
    Wirt
    • 62
    • 30
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 52
    • 45
    Monoklonal
    Konjugat
    • 63
    • 12
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser KRT20 Antikörper ist konjugiert mit FITC
    Applikation
    • 68
    • 46
    • 25
    • 15
    • 14
    • 12
    • 11
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    Spezifität
    This Monoclonal antibody represents an excellent marker for certain types of carcinomas such as adenocarcinomas of the colon, transitional cell carcinomas of the bladder and Merkel cell tumors of the skin. Very sensitive detection of intestestinal and gastric foveolar epithelium, urothelial umbrella cells, Merkel cells of epidermis as well as tumors originating therefrom (e.g. primary and metastatic colorectal carcinoma). Adenocarcinomas of breast, lung, endometrium and ovary (non-mucinous) as well as neuroendocrine tumors of the lung are essentially negative. Polypeptide Recognized: Protein IT (keratin K20, Mr 46 000, also designated Cytokeratin 20). Tested Reactivities on Cultured Cell Lines: HT-29, LoVo, DLD-1, SW 1116, CaCo-2, RT-4.
    Keine Kreuzreaktivität
    Maus
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Porcine (Pig) and Rat.
    Aufreinigung
    Affinity Chromatography
    Immunogen
    Electrophoretically purified Keratin K 20 from Human intestinal mucosa.
    Klon
    KS20-10
    Isotyp
    IgG1
    Top Product
    Discover our top product KRT20 Primärantikörper
  • Applikationshinweise
    FACS. Cytological Material. Immunohistochemistry on Frozen Sections. . Immunohistochemistry on Paraffin sections (Only after microwave treatment). Working Dilution: 1/10-1/20 in PBS, PH 7.4 for Immunohistochemistry. Incubation Time: 1h at RT or over night at 2-8 °C.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Mușină, Zlei, Mentel, Scripcariu, Ștefan, Aniţei, Filip, Radu, Gavrilescu, Panuţa, Buna-Arvinte, Cordun, Predescu, Scripcariu, Huţanu: "Evaluation of circulating tumor cells in colorectal cancer using flow cytometry." in: The Journal of international medical research, Vol. 49, Issue 9, pp. 300060520980215, (2021) (PubMed).

  • Target
    KRT20 (Keratin 20 (KRT20))
    Andere Bezeichnung
    Cytokeratin 20 (KRT20 Produkte)
    Synonyme
    KRT20 antikoerper, CD20 antikoerper, CK-20 antikoerper, CK20 antikoerper, K20 antikoerper, KRT21 antikoerper, Krt21 antikoerper, 9030623C06Rik antikoerper, keratin 20 antikoerper, KRT20 antikoerper, Krt20 antikoerper
    Hintergrund
    Cytokeratin 20 is a 46 kDa intermediate filament protein whose expression is restricted primarily to gastric and intestinal epithelium, urothelium, and Merkel cells. This antibody is highly specific to cytokeratin 20 and shows no cross-reactivity with other IFPs. Cytokeratin 20 is a unique type I keratin that is expressed in adenocarcinomas of the colon stomach, pancreas and bile system. It is also expressed in mucinous ovarian tumors, transitional cell carcinomas of the urinary tract, and Merkel cell carcinomas.Synonyms: CK20, Cytokeratin 20, K20, KRT20, Keratin type I cytoskeletal 20, Keratin-20, Protein IT
    Gen-ID
    54474
    NCBI Accession
    NP_061883
    UniProt
    P35900
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