Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) Antikörper

Antigen: Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1)

Synonyme: CX3CR1, MGC140194, V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1, Rbs11, C-C, CD128, CD181, CKR-1, CXCR1, IL8R1, CMKAR1, IL8RBA, CDw128a, C-C-CKR-1, Il8ra

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC), Durchflusszytometrie (FACS)

Produktnummer: ABIN110594

Produktbeschreibung

Weitere Bezeichnung: CX3CR1 (V28, Fractalkine Receptor)

Format: Protein A purified, 0.1% sodium azide, Lyophilized

Beschreibung: Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine1. Human CX3CR1, also named V28, was first cloned from human genomic DNA libraries2. A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor3 ,4. Human CX3CR1 has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.

Anwendungen

Lagerung: 4 C for short term storage or -20 C in small aliquots for long term storage. Avoid repeated freeze and thaw. Reconstitute to 1 mg/ml by adding 200 µ l PBS

Forschungsgebiet: Chemokine, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Held-Feindt, Hattermann, Mueerkoester et al.: "CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs)." in: Experimental cell research, 2010 (PubMed).