Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) Antikörper

Produktnummer ABIN110589

Der Kaninchen Polyklonal anti-Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) Antikörper (ABIN110589) detektiert spezifisch Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) in IP und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) Antikörper (ABIN110589)

Target: Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunoprecipitation (IP), Western Blotting (WB)

Produktdetails

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Lagerung: 4 °C

Antigendetails

Target: Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2)

Hintergrund: Gai2 is a 40-41 kDa alpha-subunit of heterotrimeric protein, that shares sequence homology with Gai3 and Gai1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gai2 is expressed widely in tissues and cell lines. Activation of PLC-ß by Gai-coupled receptors is the result of release of Gß. subunits from Gai. Gai2regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.