Laminin, beta 1 (LAMB1) Antikörper

Antigen: Laminin, beta 1 (LAMB1)

Synonyme: CLM, MGC142015, gup, fc20b05, sb:cb95, wu:fc20b05, Lamb1-1, LAMB1, lams, lamb2

Klonalität: Monoklonal (DG10)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN108416

Produktbeschreibung

Weitere Bezeichnung: Laminin (beta1 chain)

Immunogen: Monoclonal antibody (Mab) to laminin (b1-chain) is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Partially pepsin-digested laminins from human placenta were used as immunogen (8).

Format: Purified

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: DG10

Beschreibung: Monoclonal Antibody to Human Extracellular Matrix Components

Spezifität: The antibody recognizes the Mr 220000 b1-chain of laminin. Mab DG10 appears to react with the NH2-terminus of the Ln b1chain (1). The antibody reacts with human tissues

Anwendungen

Applikationshinweise: No reactivity with paraffin sections. Working dilution in westem blotting is at least 1:1000.

Lagerung: This product should be stored at +2 C to +8 C

Forschungsgebiet: Extrazelluläre Matrix

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Laminin §1-chain in normal human kidney (MAb DG10, laminin §1)

Publikationen

Publikationen: Holmbom B, Naslund U, Eriksson A et al.: "Comparison of triphenyltetrazolium chloride (TTC) staining versus detection of fibronectin in experimental myocardial infarction." in: Histochemistry, Vol. 99, Issue 4, pp. 265-75, 1993 (PubMed).

Virtanen I, Lohi J, Tani T et al.: "Distinct changes in the laminin composition of basement membranes in human seminiferous tubules during development and degeneration." in: Am J Pathol, Vol. 150, Issue 4, pp. 1421-31, 1997 (PubMed).

Tani T, Lehto VP, Virtanen I: "Expression of laminins 1 and 10 in carcinoma cells and comparison of their roles in cell adhesion." in: Exp Cell Res, Vol. 248, Issue 1, pp. 115-21, 1999 (PubMed).

Konttinen YT, Li TF, Xu JW et al.: "Expression of laminins and their integrin receptors in different conditions of synovial membrane and synovial membrane-like interface tissue." in: Ann Rheum Dis, Vol. 58, Issue 11, pp. 683-90, 1999 (PubMed).

Geberhiwot T, Ingerpuu S, Pedraza C et al.: "Blood platelets contain and secrete laminin-8 (alpha4beta1gamma1) and adhere to laminin-8 via alpha6beta1 integrin." in: Exp Cell Res, Vol. 253, Issue 2, pp. 723-32, 1999 (PubMed).

Auranen M, Rapola J, Pihko H et al.: "Muscle membrane-skeleton protein changes and histopathological characterization of muscle-eye-brain disease." in: Neuromuscul Disord, Vol. 10, Issue 1, pp. 16-23, 2000 (PubMed).

Leivo T, Kiistala U, Vesterinen M et al.: "Re-epithelialization rate and protein expression in the suction-induced wound model: comparison between intact blisters, open wounds and calcipotriol-pretreated open wounds." in: Br J Dermatol, Vol. 142, Issue 5, pp. 991-1002, 2000 (PubMed).

Geberhiwot T, Wondimu Z, Salo S et al.: "Chain specificity assignment of monoclonal antibodies to human laminins by using recombinant laminin beta1 and gamma1 chains." in: Matrix Biol, Vol. 19, Issue 2, pp. 163-7, 2000 (PubMed).

Korhonen M, Ormio M, Burgeson RE et al.: "Unaltered distribution of laminins, fibronectin, and tenascin in celiac intestinal mucosa." in: J Histochem Cytochem, Vol. 48, Issue 7, pp. 1011-20, 2000 (PubMed).