anti-NOD2 (NOD2) Antikörper

anti-Nucleotide-Binding Oligomerization Domain Containing 2 Antikörper (NOD2)
Auf finden Sie aktuell 149 Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NOD2 Kits (4) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 164 NOD2 Produkte verfügbar.
ACUG, BLAU, Card15, CD, CLR16.3, F830032C23Rik, IBD1, Nlrc2, NOD2B, PSORAS1
Alle Antikörper anzeigen Gen GeneID UniProt
NOD2 64127 Q9HC29
NOD2 257632  
NOD2 291912  

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Meistgesuchte Reaktivitäten zu anti-NOD2 (NOD2) Antikörper

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anti-Human NOD2 Antikörper:

anti-Mouse (Murine) NOD2 Antikörper:

anti-Rat (Rattus) NOD2 Antikörper:

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Am meisten referenzierte anti-NOD2 Antikörper

  1. Human Monoclonal NOD2 Primary Antibody für FACS, ICC - ABIN151959 : McDonald, Chen, Ollendorff, Ogura, Marchetto, Lécine, Borg, Nuñez: A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 13 Referenzen für 151959

  2. Human Polyclonal NOD2 Primary Antibody für ICC, IF - ABIN153051 : Till, Rosenstiel, Bräutigam, Sina, Jacobs, Oberg, Seegert, Chakraborty, Schreiber: A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion. in Journal of cell science 2008 (PubMed)
    Zeige alle 5 Referenzen für 153051

  3. Human Polyclonal NOD2 Primary Antibody für IF, WB - ABIN318706 : Inohara, Nuñez: NODs: intracellular proteins involved in inflammation and apoptosis. in Nature reviews. Immunology 2003 (PubMed)
    Zeige alle 3 Referenzen für 318706

  4. Human Polyclonal NOD2 Primary Antibody für ELISA, WB - ABIN251672 : Keshav: Paneth cells: leukocyte-like mediators of innate immunity in the intestine. in Journal of leukocyte biology 2006 (PubMed)
    Zeige alle 3 Referenzen für 251672

  5. Human Polyclonal NOD2 Primary Antibody für ELISA, ICC - ABIN4340247 : Rahman, Midtling, Svingen, Xiong, Bell, Tung, Smyrk, Egan, Faubion: The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

  6. Human Monoclonal NOD2 Primary Antibody für ICC, IF - ABIN1721812 : Cooney, Baker, Brain, Danis, Pichulik, Allan, Ferguson, Campbell, Jewell, Simmons: NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. in Nature medicine 2010 (PubMed)

  7. Human Monoclonal NOD2 Primary Antibody für FACS, ICC - ABIN4340264 : Subramanian, Bergman, Henriques-Normark: Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils. in Journal of innate immunity 2017 (PubMed)

Weitere Antikörper gegen NOD2 Interaktionspartner

Human Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Interaktionspartner

  1. NOD2 is an important mediator in the viral uptake and inflammatory response during the pathogenesis of CVB3 myocarditis.

  2. We identified 2 missense mutations at 16q12 in NOD2 (p.Ala110Thr and p.Arg311Trp), which encodes nucleotide-binding oligomerization domain protein 2. We further examined 94 genetically unrelated AgP patients by targeted sequencing of NOD2 and found that 2 patients among them also carried the p.Arg311Trp variant. Furthermore, we found 3 additional missense mutations in this gene (p.His370Tyr, p.Arg459Cys, and p.Ala868Thr)

  3. Performed genetic analysis in patients with Crohn's disease (CD) to determine effect of NOD2/CARD15 polymorphisms on treatment response to adalimumab and infliximab.

  4. The study of the correlation between genotype and phenotypic expression showed that CARD15 mutation is associated with ileocecal Crohn's disease, with fistulizing and stenosing behavior in Crohn's disease as well as with severe evolution

  5. Ligand-driven triggering of TLR-3 (zeige TLR3 Antikörper), -4, NOD2, and DC-SIGN (zeige CD209 Antikörper), despite reducing viral replication, markedly increased the capacity of infected dendritic cells to stimulate HIV-specific cytotoxic T-cells.

  6. This work suggests that Crohn's Disease-associated Nod2 variants could be stabilized in vivo with a molecular chaperone (zeige HSP90AA1 Antikörper).

  7. From the results, the authors conclude that SNPs at the NOD2 and IL6 (zeige IL6 Antikörper) genes are associated with leprosy reactions as an outcome.

  8. NOD2 rs3135500 and IL12B (zeige IL12B Antikörper) rs1368439 SNPs were not genetic risk factors for colorectal cancer in the studied Iranian population.

  9. Variants of NOD2/CARD15 and TLR4 (zeige TLR4 Antikörper) do not confer susceptibility to inflammatory bowel disease, but appear to determine Crohn's disease phenotypes in this southeastern Brazilian population.

  10. IFNgamma positively affects NOD2-mediated signaling in human conventional dendritic cells, in a manner considerably dependent on XIAP (zeige XIAP Antikörper) and partially dependent on mTOR (zeige FRAP1 Antikörper).

Mouse (Murine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Interaktionspartner

  1. Results show that the simultaneous absence of Nod1 (zeige NOD1 Antikörper) and Nod2 is associated with accelerated T cell death upon alloantigen encounter, suggesting these proteins might provide new targets to ameliorate T cell responses in a variety of inflammatory states, including those associated with bone marrow or solid organ transplantation.

  2. These data suggest that NOD2 contributes to bone loss in estrogen deficiency by elevating reactive oxygen species levels in OCs.

  3. NOD2 is an important mediator in the viral uptake and inflammatory response during the pathogenesis of CVB3 myocarditis.

  4. this study shows that the effect of the gut (zeige GUSB Antikörper) microbiota on bone is dependent on NOD1 (zeige NOD1 Antikörper) and NOD2 signaling

  5. this study shows that microbial sensing by Nod2 is an important mechanism to regulate small intestinal mucosal damage following acute T cell activation

  6. results demonstrate that the recognition of bacterial products by NOD2 inside the PLNs contributes to T1D development, establishing a new putative target for intervention during the early stages of the disease.

  7. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (zeige AKT1 Antikörper)-mTOR (zeige FRAP1 Antikörper)-FOXO1 (zeige FOXO1 Antikörper) signaling and suppressing the activation of TLR4 (zeige TLR4 Antikörper) and/or NOD2 signaling pathways.

  8. this study shows that innate immunity activation by muramyl peptides is mediated via an interaction between YB1 (zeige YBX1 Antikörper) and NOD2

  9. this study shows that NOD2 is important for osteoclast differentiation and inflammatory bone resorption in vivo and also for the macrophage response to Gram-negative bacteria

  10. this study reveals that LRRK2 (zeige LRRK2 Antikörper) is a new positive regulator of Rip2 (zeige ARHGDIG Antikörper) and promotes inflammatory cytokine induction through the Nod1 (zeige NOD1 Antikörper)/2-Rip2 (zeige ARHGDIG Antikörper) pathway.

Cow (Bovine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Interaktionspartner

  1. Data indicate six single-nucleotide polymorphisms (SNPs) in the caspase recruitment domain 15 protein (CARD15) gene associated with susceptibility to bovine tuberculosis (BTB) in Chinese Holstein cows.

  2. Data indicate that the Nod2 signaling adaptor protein (NOD2) G-->A at position 1594 bp plays a critical role in increasing 305-day milk yields.

  3. Genetic variation and putative regulatory regions in bovine CARD15.

  4. A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype.

NOD2 Antigen-Profil

Beschreibung des Gens

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Alternative names and synonyms associated with NOD2

  • caspase recruitment domain 15 protein (TTHERM_01951320) Antikörper
  • nucleotide-binding oligomerization domain containing 2 (NOD2) Antikörper
  • nucleotide-binding oligomerization domain containing 2 (Nod2) Antikörper
  • ACUG Antikörper
  • BLAU Antikörper
  • Card15 Antikörper
  • CD Antikörper
  • CLR16.3 Antikörper
  • F830032C23Rik Antikörper
  • IBD1 Antikörper
  • Nlrc2 Antikörper
  • NOD2B Antikörper
  • PSORAS1 Antikörper

Bezeichner auf Proteinebene für NOD2

caspase recruitment domain 15 protein , NLR family, CARD domain containing 2 , NOD-like receptor C2 , caspase recruitment domain family, member 15 , caspase recruitment domain protein 15 , caspase recruitment domain-containing protein 15 , inflammatory bowel disease protein 1 , nucleotide-binding oligomerization domain 2 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2 , nucleotide-binding oligomerization domain-containing protein 2

7828465 Tetrahymena thermophila
64127 Homo sapiens
257632 Mus musculus
291912 Rattus norvegicus
444867 Bos taurus
454083 Pan troglodytes
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