anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) Antikörper

TIMP1 belongs to the TIMP gene family. Zusätzlich bieten wir Ihnen TIMP1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TIMP1 7076 P01033
Anti-Ratte TIMP1 TIMP1 116510 P30120
Anti-Maus TIMP1 TIMP1 21857 P12032
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 4 bis 5 Tage
209,00 €
Details

TIMP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human


Am meisten referenzierte anti-TIMP1 Antikörper

  1. Human Monoclonal TIMP1 Primary Antibody für ELISA, WB - ABIN108398 : Clark, Powell, Wright, Cawston: Polyclonal and monoclonal antibodies against human tissue inhibitor of metalloproteinases (TIMP) and the design of an enzyme-linked immunosorbent assay to measure TIMP. in Matrix (Stuttgart, Germany) 1991 (PubMed)

Weitere Antikörper gegen TIMP1 Interaktionspartner

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Low MMP-8 (zeige MMP8 Antikörper)/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome

  2. Data show that the mean values for TIMP1, TIMP2 (zeige TIMP2 Antikörper) and MMP2 (zeige MMP2 Antikörper) were lower in survivors, MMP9 (zeige MMP9 Antikörper) was higher in survivors.

  3. We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7 (zeige MMP7 Antikörper), MMP-10 (zeige MMP10 Antikörper) and TIMP-1 correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the diseaseMMP-10, MMP-7 (zeige MMP7 Antikörper), TIMP-1, TIMP-2 (zeige TIMP2 Antikörper) were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.

  4. plasma concentrations of MMP-7 (zeige MMP7 Antikörper), MMP-8 (zeige MMP8 Antikörper), -9 and TIMP-1 within 96 h from the onset of acute pancreatitis symptoms are elevated in acute pancreatitis patients compared with healthy controls

  5. High TIMP1 expression is associated with hepatic fibrosis.

  6. TIMP-1 was highly expressed in TNBC patients and was associated with a poor prognosis.

  7. Results suggest a crucial role of MMP9 (zeige MMP9 Antikörper) at the early stage of carcinogenesis in the large intestine. The increase in MMP9 (zeige MMP9 Antikörper) and TIMP1 mRNA concentration and the decrease in MMP28 (zeige MMP28 Antikörper) in the large intestinal tissue may be a confirmation of cancer.

  8. Expression of TIMP1 is i (zeige CD63 Antikörper)ncreased in chronic pancreatitis, pancreatic intra-epithelial neoplasia, and pancreatic ductal adenocarcinoma tissues from patients. TIMP1 signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  9. Our study provides information on the dynamic changes of MMP-9 (zeige MMP9 Antikörper)-TIMP-1 system and S100B (zeige S100B Antikörper) in the perioperative period. Preoperative reduction of TIMP-1 might be predictive for shunt requirement but future studies are required for verification.

  10. Serum TIMP1 did not differ significantly between normal weight, overweight, and obese participants.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Decreased MMP-9 (zeige MMP9 Antikörper) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (zeige EGF Antikörper) on MMP-9 (zeige MMP9 Antikörper) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (zeige TNF Antikörper), and hepatocyte growth factor (zeige HGF Antikörper) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (zeige TIMP2 Antikörper) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (zeige TIMP2 Antikörper) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (zeige TIMP2 Antikörper) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (zeige MMP9 Antikörper), TIMP1, and NGAL (zeige LCN2 Antikörper) (also MMP2 (zeige MMP2 Antikörper) in 220 kDa complex) without proteolytic activity.

  2. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (zeige VEGFA Antikörper), pro-MMP-9 (zeige MMP9 Antikörper), MMP-2 (zeige MMP2 Antikörper), VEGFR-1 (zeige FLT1 Antikörper), VEGFR-2 (zeige KDR Antikörper), and TIMP-1, which may contribute to the development of venous stenosis.

  3. Results indicate that leukemia inhibitory factor (LIF (zeige LIF Antikörper)) and Oncostatin M (zeige OSM Antikörper) increase the expression of MMP-1 (zeige MMP1 Antikörper), MMP-3 (zeige MMP3 Antikörper), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (zeige LIF Antikörper) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (zeige MMP2 Antikörper), MMP-9 (zeige MMP9 Antikörper) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. proteomic analysis of the mesenchymal stem cells secretome identified the TIMP-1 as a potential effector molecule responsible for the anti-angiogenic properties of MSC (zeige MSC Antikörper)

  2. TIMP1 signaling via CD63 (zeige CD63 Antikörper) leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  3. This study highlights a previously undescribed integral role for TIMP1 in both vascular network maturation and adaptations to ischemia or alterations in flow.

  4. TIMP-1 was identified as a selectively upregulated component secreted from immature astrocytes from human pluripotent stem cells.

  5. demonstrate that TIMP-2 (zeige TIMP2 Antikörper) plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis

  6. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (zeige CD63 Antikörper).

  7. TIMP-1 is a ligand of LRP-1 (zeige LRP1 Antikörper) and we highlight a new example of its MMP-independent, cytokine-like functions.

  8. RAB37 (zeige RAB37 Antikörper) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (zeige MMP9 Antikörper) migration axis in vitro and in vivo and to suppress tumor metastasis.

  9. PDGF-D (zeige PDGFD Antikörper) intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2 (zeige MMP2 Antikörper)/MMP (zeige MMP2 Antikörper)-9 (zeige MMP9 Antikörper) system, and PDGF-D (zeige PDGFD Antikörper) signaling is mediated through both PDGF (zeige PDGFA Antikörper)-alpha and -beta receptors.

  10. Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (zeige MAPK14 Antikörper) signaling pathway.

TIMP1 Antigen-Profil

Protein Überblick

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Genbezeichner und Symbole assoziert mit TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) Antikörper
  • TIMP metallopeptidase inhibitor 1 (Timp1) Antikörper
  • tissue inhibitor of metalloproteinase 1 (LOC100009047) Antikörper
  • tissue inhibitor of metalloproteinase 1 (Timp1) Antikörper
  • Clgi Antikörper
  • DKFZp468A0912 Antikörper
  • EPA Antikörper
  • EPO Antikörper
  • HCI Antikörper
  • Timp Antikörper
  • TIMP-1 Antikörper
  • TIMP1 Antikörper

Bezeichner auf Proteinebene für TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

GENE ID SPEZIES
574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
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