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anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) Antikörper

TIMP1 belongs to the TIMP gene family. Zusätzlich bieten wir Ihnen TIMP1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TIMP1 7076 P01033
Anti-Ratte TIMP1 TIMP1 116510 P30120
Anti-Maus TIMP1 TIMP1 21857 P12032
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 4 bis 5 Tage
209,00 €

TIMP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität

Am meisten referenzierte anti-TIMP1 Antikörper

  1. Human Monoclonal TIMP1 Primary Antibody für ELISA, WB - ABIN108398 : Clark, Powell, Wright, Cawston: Polyclonal and monoclonal antibodies against human tissue inhibitor of metalloproteinases (TIMP) and the design of an enzyme-linked immunosorbent assay to measure TIMP. in Matrix (Stuttgart, Germany) 1991 (PubMed)

Weitere Antikörper gegen TIMP1 Interaktionspartner

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. MMP-9 (zeige MMP9 Antikörper) activation rather than TIMP-1 may by associated with the pathomechanism of retinal ganglion cell and optic nerve damage in absolute glaucoma.

  2. Here we report isothermal titration calorimetric studies of the effects of selectivity-modifying mutations in NTIMP1 and NTIMP2 on the thermodynamics of their interactions with MMP1 (zeige MMP1 Antikörper), MMP3 (zeige MMP3 Antikörper), and MMP14 (zeige MMP14 Antikörper).

  3. Normalization of bone marrow microenvironment is paralleled by decreased expression of TIMP and PDGFA (zeige PDGFA Antikörper).

  4. significant differences were detected concerning the activity of TIMPs resulting in a negative correlation of TIMP1 activity with MMP2 (zeige MMP2 Antikörper) activity (p = 0.044) and negative correlations of TIMP2 (zeige TIMP2 Antikörper) and TIMP3 (zeige TIMP3 Antikörper) with MMP9 (zeige MMP9 Antikörper) activity

  5. activation of TLR7 upregulated the expression levels of IFN-lambda1 and MMP-9 were increased by ~3 fold, whereas other genes (p53, PTEN, TIMP-1) were upregulated by ~2 fold, and VEGF was marginally upregulated after 10 min.

  6. The expression levels MMP-9 (zeige MMP9 Antikörper), TIMP-1, and TIMP-2 (zeige TIMP2 Antikörper) in both marrow plasma and culture supernatants were significantly higher in MM patients than controls.

  7. suggest better clinical usefulness of MMP-9 (zeige MMP9 Antikörper) and TIMP-1 expression in cholesteatoma tissues than either serum or plasma levels of these proteins

  8. These results suggest that in the progression of renal aging, high expression of TIMP-1 up-regulates PTEN (zeige PTEN Antikörper) expression indicating that PTEN (zeige PTEN Antikörper) and TIMP-1 are involved in the aging-associated impairment of renal angiogenesis

  9. MMP-1 (zeige MMP1 Antikörper) expression is increased in intervertebral disc degeneration, with higher expression observed in more severe cases, whereas TIMP-1 expression was similarly expressed in both normal and degenerated discs.

  10. Metformin simultaneously increases VEGFA (zeige VEGFA Antikörper) and reduces CXCL10 (zeige CXCL10 Antikörper) and TIMP1 in CD34 (zeige CD34 Antikörper)(+) cells in a model of the diabetic state combined with hypoxia to stimulate angiogenesis.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Decreased MMP-9 (zeige MMP9 Antikörper) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (zeige EGF Antikörper) on MMP-9 (zeige MMP9 Antikörper) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (zeige TNF Antikörper), and hepatocyte growth factor (zeige HGF Antikörper) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (zeige TIMP2 Antikörper) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (zeige TIMP2 Antikörper) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (zeige TIMP2 Antikörper) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (zeige MMP9 Antikörper), TIMP1, and NGAL (zeige LCN2 Antikörper) (also MMP2 (zeige MMP2 Antikörper) in 220 kDa complex) without proteolytic activity.

  2. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (zeige VEGFA Antikörper), pro-MMP-9 (zeige MMP9 Antikörper), MMP-2 (zeige MMP2 Antikörper), VEGFR-1 (zeige FLT1 Antikörper), VEGFR-2 (zeige KDR Antikörper), and TIMP-1, which may contribute to the development of venous stenosis.

  3. Results indicate that leukemia inhibitory factor (LIF (zeige LIF Antikörper)) and Oncostatin M (zeige OSM Antikörper) increase the expression of MMP-1 (zeige MMP1 Antikörper), MMP-3 (zeige MMP3 Antikörper), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (zeige LIF Antikörper) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (zeige MMP2 Antikörper), MMP-9 (zeige MMP9 Antikörper) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. demonstrate that TIMP-2 (zeige TIMP2 Antikörper) plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis

  2. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (zeige CD63 Antikörper).

  3. TIMP-1 is a ligand of LRP-1 (zeige LRP1 Antikörper) and we highlight a new example of its MMP-independent, cytokine-like functions.

  4. RAB37 (zeige RAB37 Antikörper) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (zeige MMP9 Antikörper) migration axis in vitro and in vivo and to suppress tumor metastasis.

  5. PDGF-D (zeige PDGFD Antikörper) intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2 (zeige MMP2 Antikörper)/MMP (zeige MMP2 Antikörper)-9 (zeige MMP9 Antikörper) system, and PDGF-D (zeige PDGFD Antikörper) signaling is mediated through both PDGF (zeige PDGFA Antikörper)-alpha and -beta receptors.

  6. Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (zeige MAPK14 Antikörper) signaling pathway.

  7. Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 (zeige TIMP3 Antikörper)-deficient mice.

  8. TNF-alpha (zeige TNF Antikörper) produced by cholestasis can promote liver fibrosis via TIMP-1 production from hepatic stellate cells.

  9. These data suggest an MMP-independent role of TIMP-1 in regulating CD4 (zeige CD4 Antikörper) T cell access into the CNS parenchyma during acute JHMV encephalitis

  10. miR (zeige MLXIP Antikörper)-21 contributes to renal fibrosis by mediating MMP9 (zeige MMP9 Antikörper)/TIMP1

TIMP1 Antigen-Profil

Protein Überblick

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Genbezeichner und Symbole assoziert mit TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) Antikörper
  • TIMP metallopeptidase inhibitor 1 (Timp1) Antikörper
  • tissue inhibitor of metalloproteinase 1 (LOC100009047) Antikörper
  • tissue inhibitor of metalloproteinase 1 (Timp1) Antikörper
  • Clgi Antikörper
  • DKFZp468A0912 Antikörper
  • EPA Antikörper
  • EPO Antikörper
  • HCI Antikörper
  • Timp Antikörper
  • TIMP-1 Antikörper
  • TIMP1 Antikörper

Bezeichner auf Proteinebene für TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
Ausgewählte Anbieter für anti-TIMP1 (TIMP1) Antikörper
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