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anti-Methionine Adenosyltransferase I, alpha (MAT1A) Antikörper

MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. Zusätzlich bieten wir Ihnen Methionine Adenosyltransferase I, alpha Kits (20) und Methionine Adenosyltransferase I, alpha Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MAT1A 17420 P51949
MAT1A 4143 Q00266
MAT1A 25331 P13444
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Top anti-Methionine Adenosyltransferase I, alpha Antikörper auf

Showing 10 out of 53 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB MAT1A Antibody (N-term) (ABIN656632) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Caenorhabditis elegans Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Huhn Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with MAT1A Antibody (N-term) followed which was peroxidase conjugated to the secondary antibody and  followed by DAB staining. Western blot analysis of MAT1A Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the MAT1A antibody detected the MAT1A protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: MAT1A Antibody [NBP1-55120] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification. Western Blot: MAT1A Antibody [NBP1-55120] - WB analysis of MAT1A in mouse liver lysate. Image courtesy of product review submitted by Hua Jiang. 100 μL Anmelden zum Anzeigen 3 bis 6 Tage
388,75 €
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Mat1 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa/HepG2/293 cells, using MAT1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Human Maus Unkonjugiert EIA, IF, WB 0.1 mL Anmelden zum Anzeigen 8 bis 10 Tage
440,00 €
Human Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €

MAT1A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)

Human ,
, , , , ,
Rat (Rattus)

Am meisten referenzierte anti-Methionine Adenosyltransferase I, alpha Antikörper

  1. Human Polyclonal MAT1A Primary Antibody für EIA, IHC (p) - ABIN953327 : Wu, Huang, Lu, Chien, Yeh, Tsai, Liao, Chen, Liao, Cheng, Lin: Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines. in Cellular and molecular life sciences : CMLS 2010 (PubMed)
    Zeige alle 4 Referenzen für ABIN953327

  2. Human Monoclonal MAT1A Primary Antibody für EIA, IF - ABIN1108162 : Chamberlin, Ubagai, Mudd, Levy, Chou: Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene. in American journal of human genetics 1997 (PubMed)
    Zeige alle 3 Referenzen für ABIN1108162

  3. Human Polyclonal MAT1A Primary Antibody für ICC, IF - ABIN4332790 : Yang, Cho, Li, Peng, Ko, Mato, Lu: MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma. in The Journal of clinical investigation 2013 (PubMed)
    Zeige alle 2 Referenzen für ABIN4332790

  4. Caenorhabditis elegans (C. elegans) Polyclonal MAT1A Primary Antibody für IHC, WB - ABIN2776785 : Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005 (PubMed)

  5. Human Polyclonal MAT1A Primary Antibody für IHC (p), WB - ABIN656632 : Bing, Zhu, Yu, Li, Liu, Li, Wang, Qi, Guo, Yuan, He, Liu, Liu: Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells. in The Journal of biological chemistry 2014 (PubMed)

Weitere Antikörper gegen Methionine Adenosyltransferase I, alpha Interaktionspartner

Mouse (Murine) Methionine Adenosyltransferase I, alpha (MAT1A) Interaktionspartner

  1. MAT1A is required for normal VLDL assembly and plasma lipid homeostasis in mice. Impaired VLDL synthesis, mainly due to SAMe deficiency, contributes to NAFLD (zeige TSC2 Antikörper) development in MAT1A-KO mice.

  2. Deletion of the TFIIH kinase subunit Mat1 in mouse fibroblasts leads to dramatically reduced RNA polymerase II Ser5 phosphorylation.

  3. DUSP1 (zeige DUSP1 Antikörper) mRNA and protein levels are lower in Mat1a knockout livers and fall rapidly in cultured hepatocytes.

  4. investigated the function of the Cdk7 (zeige CDK7 Antikörper).cyclin (zeige PCNA Antikörper) H.Mat1 complex in murine embryonic stem (ES) cells and preimplantation embryos to determine whether it regulates the unique cell cycle structure and transcriptional network of pluripotent cells

  5. This study demonstrates a requirement for MAT1 in the operation of PGC-1 (zeige PPARGC1A Antikörper) coactivators that control cell metabolism.

  6. study found that Mat1 and Cdk7 (zeige CDK7 Antikörper) levels are undetectable in adipose tissues in vivo and downregulated during adipogenesis

  7. Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A

  8. MAT1A knockout hepatocytes have more baseline DNA synthesis but no mitogenic response to hepatocyte growth factor (zeige HGF Antikörper). MAT1A-produced SAMe has a major role in ERK (zeige EPHB2 Antikörper) signaling & cyclin D1 (zeige CCND1 Antikörper) regulation during liver regeneration & mitogenic signal response.

  9. Mat1a(-/-) mice have expansion of liver stem cells as they age. These cells have increased expression of several oncogenes and are tumorigenic in vivo.

  10. C/EBPbeta (zeige CEBPB Antikörper) plays an important role in epigenetic regulation of the mature hepatic gene MAT1A

Human Methionine Adenosyltransferase I, alpha (MAT1A) Interaktionspartner

  1. S-adenosyl-L-methionine (zeige AS3MT Antikörper) diminishes hepatitis C virus expression by altering MAT1A/2A signaling in hepatocytes.

  2. Data suggest the role of the phospholipase C epsilon (zeige PLCL1 Antikörper)-Protein kinase D (zeige PRKD1 Antikörper)-PEA15 (zeige PEA15 Antikörper) protein-ribosomal S6 kinase (zeige RPS6KB1 Antikörper)-IkappaB-NF-kappa B (zeige NFKB1 Antikörper) pathway in facilitating inflammation and inflammation-associated carcinogenesis in the colon.

  3. Integrin alpha5beta1 and p53 (zeige TP53 Antikörper) convergent pathways in the control of anti-apoptotic proteins PEA-15 (zeige PEA15 Antikörper) and survivin (zeige BIRC5 Antikörper) in high-grade glioma.

  4. High PED expression is associated with esophageal carcinoma.

  5. The nuclear translocation of SApErk1/ 2 apart from PEA-15 (zeige PEA15 Antikörper) as an important mechanism to reverse senescence phenotype.

  6. Latent HCMV infection of CD34 (zeige CD34 Antikörper) + cells protects cells from FAS (zeige FAS Antikörper)-mediated apoptosis through the cellular IL-10 (zeige IL10 Antikörper)/PEA-15 (zeige PEA15 Antikörper) pathway.

  7. New therapeutic targets based around PEA-15 (zeige PEA15 Antikörper) and its associated interactions are now being uncovered and could provide novel avenues for treatment strategies in multiple diseases.

  8. PED/PEA-15 overexpression is sufficient to block hydrogen peroxide-induced apoptosis in Ins-1E cells through a PLD-1 mediated mechanism

  9. Omi/HtrA2 (zeige HTRA2 Antikörper) overexpression promotes hepatocellular carcinoma cell apoptosis and the ped/pea-15 expression level causes this difference of the Omi/HtrA2 (zeige HTRA2 Antikörper) pro-apoptotic marker in the various hepatocellular carcinoma cell lines

  10. Results suggest that neurochemical adaptations of brain FADD (zeige FADD Antikörper), as well as its interaction with PEA-15 (zeige PEA15 Antikörper), could play a major role to counteract the known activation of the mitochondrial apoptotic pathway in major depression

Methionine Adenosyltransferase I, alpha (MAT1A) Antigen-Profil

Protein Überblick

This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.

Genbezeichner und Symbole assoziert mit MAT1A

  • menage a trois 1 (Mnat1) Antikörper
  • methionine adenosyltransferase I, alpha (mat1a) Antikörper
  • methionine adenosyltransferase I, alpha (MAT1A) Antikörper
  • methionine adenosyltransferase I, alpha (Mat1a) Antikörper
  • phosphoprotein enriched in astrocytes 15 (PEA15) Antikörper
  • AdoMet Antikörper
  • AI046368 Antikörper
  • Ams Antikörper
  • E130115E11Rik Antikörper
  • HMAT1 Antikörper
  • HUMMAT1H Antikörper
  • MAT Antikörper
  • MAT1 Antikörper
  • MAT1H Antikörper
  • MATA1 Antikörper
  • P36 Antikörper
  • PEA-15 Antikörper
  • PED Antikörper
  • SADE Antikörper
  • SAMS Antikörper
  • SAMS1 Antikörper
  • SAS Antikörper
  • wu:fi35e01 Antikörper
  • zgc:55442 Antikörper

Bezeichner auf Proteinebene für MAT1A

CDK-activating kinase assembly factor MAT1 , CDK7/cyclin H assembly factor , CDK7/cyclin-H assembly factor , RING finger protein MAT1 , p35 , S-adenosylmethionine synthase isoform type-1 , MAT 1 , MAT-I/III , S-adenosylmethionine synthetase isoform type-1 , adoMet synthase 1 , adoMet synthetase 1 , methionine adenosyltransferase 1 , methionine adenosyltransferase I/III , S - adenosylmethionine synthetase , 15 kDa phosphoprotein enriched in astrocytes , Phosphoprotein enriched in astrocytes, 15kD , astrocytic phosphoprotein PEA-15 , homolog of mouse MAT-1 oncogene , phosphoprotein enriched in diabetes

17420 Mus musculus
334195 Danio rerio
423628 Gallus gallus
4143 Homo sapiens
608788 Canis lupus familiaris
100156922 Sus scrofa
541078 Bos taurus
11720 Mus musculus
25331 Rattus norvegicus
8682 Homo sapiens
Ausgewählte Anbieter für anti-Methionine Adenosyltransferase I, alpha (MAT1A) Antikörper
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