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MDS1 and EVI1 Complex Locus (MECOM) ELISA Kits

The protein encoded by MECOM is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. Zusätzlich bieten wir Ihnen MDS1 and EVI1 Complex Locus Antikörper (118) und MDS1 and EVI1 Complex Locus Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MECOM 2122 Q03112 , Q13465
MECOM 14013 Q9Z1L8
Anti-Ratte MECOM MECOM 294924  
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Top MDS1 and EVI1 Complex Locus ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Menge Anbieter Lieferzeit Preis Details
Human
96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
788,70 €
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Maus
96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
788,70 €
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Weitere ELISA Kits für MDS1 and EVI1 Complex Locus Interaktionspartner

Zebrafish MDS1 and EVI1 Complex Locus (MECOM) Interaktionspartner

  1. nephrogenesis in zebrafish is regulated by interactions between retinoic acid, mecom, and Notch (zeige NOTCH1 ELISA Kits) signaling

  2. Prdm3 and prdm16 (zeige PRDM16 ELISA Kits) are strongly expressed in the pharyngeal arches during cranioskeletal development, and their knockdown leads to defects in both the viscerocranium and the neurocranium.

Human MDS1 and EVI1 Complex Locus (MECOM) Interaktionspartner

  1. MECOM gene harbors both somatic frameshift mutations.

  2. the effects of various aberrations in ETV6 (zeige ETV6 ELISA Kits) and RUNX1 (zeige RUNX1 ELISA Kits) gene copy number on disease prognosis were evaluated in 21 pediatric patients diagnosed with B-cell ALL with/without t(12;21).

  3. The RUNX1 (zeige RUNX1 ELISA Kits) fusion transcript encodes a truncated protein containing the Runt (zeige RUNX1 ELISA Kits) homology domain responsible for both heterodimerization with CBFB (zeige CBFB ELISA Kits) and DNA binding, but lacking the proline-, serine-, and threonine-rich (PST (zeige SULT1A1 ELISA Kits)) region which is the transcription activation domain at the C terminal end

  4. novel RUNX1 (zeige RUNX1 ELISA Kits) isoforms contribute in controlling CD56 (zeige NCAM1 ELISA Kits) expression in acute myeloid leukemia (zeige BCL11A ELISA Kits) cells.

  5. this paper shows that RUNX1 (zeige RUNX1 ELISA Kits) is associated with the pathogenesis of immune thrombocytopenia possibly through regulation of Th17 cell differentiation

  6. We show that RUNX1 (zeige RUNX1 ELISA Kits) P1 expression is associated with colon cancer free survival suggesting a role for RUNX1 (zeige RUNX1 ELISA Kits) in aspirin's protective effect in colon cancer. Our studies reveal an effect of aspirin on RUNX1 (zeige RUNX1 ELISA Kits) and gene expression that may additionally explain aspirin's effects in cardiovascular disease and cancer.

  7. we identified rs2249650 and rs2268276 as new AML (zeige RUNX1 ELISA Kits) susceptibility-associated SNPs. Genome editing at rs2249650 and rs2268276 may be performed in future to uncover the effect of this potential RUNX1 (zeige RUNX1 ELISA Kits) enhancer region.

  8. RUNX1 (zeige RUNX1 ELISA Kits) and FKBP7 (zeige FKBP7 ELISA Kits), involved in erythropoesis and muscle protein synthesis, respectively, are related to change in cardiorespiratory fitness in response to exercise.

  9. HTLF (zeige FOXN2 ELISA Kits) is a RUNX1 (zeige RUNX1 ELISA Kits) target whose down-regulation promotes genomic instability and correlates with complex cytogenetic abnormalities in acute myeloid leukemia (zeige BCL11A ELISA Kits) patients.

  10. High RUNX1 (zeige RUNX1 ELISA Kits) expression is associated with breast cancer.

Mouse (Murine) MDS1 and EVI1 Complex Locus (MECOM) Interaktionspartner

  1. the DNA sequences to which EVI1 binds at +35 and +37 kb and show that mutation of one of these releases Cebpa (zeige CEBPA ELISA Kits) from EVI1-induced suppression.

  2. Evi1(+)DA-3 cells modified to express an intracellular form of GM-CSF (zeige CSF2 ELISA Kits), acquired growth factor independence and transplantability and caused an overt leukemia in syngeneic hosts, without increasing serum GM-CSF (zeige CSF2 ELISA Kits) levels.

  3. Survivin (zeige BIRC5 ELISA Kits) partially regulates HSC (zeige FUT1 ELISA Kits) function by modulating the Evi-1 transcription factor and its downstream targets

  4. Thrombopoietin (zeige THPO ELISA Kits)/MPL (zeige MPL ELISA Kits) signaling confers growth and survival capacity to CD41-positive cells in a mouse model of Evi1 leukemia.

  5. Prdm16 (zeige PRDM16 ELISA Kits) and Prdm3 control postnatal BAT (zeige BAAT ELISA Kits) identity and function.

  6. Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

  7. PR-domain protein ME has an essential role in mixed-lineage leukemia (MLL (zeige MLL ELISA Kits)) fusion protein (MFP) leukemia

  8. Cotransduction of Evi1 and the shortest isoform of C/EBPbeta (zeige CEBPB ELISA Kits), liver inhibitory protein (LIP), induced acute myeloid leukemia (zeige BCL11A ELISA Kits) with short latencies in a mouse bone marow transplantation model.

  9. Transient Evi1 transfection inhibited TGF-beta (zeige TGFB1 ELISA Kits)-induced transcriptional activity and reversed the growth inhibitory effect of TGF-beta (zeige TGFB1 ELISA Kits) in MC-26 (zeige Glycam1 ELISA Kits) mouse colon cancer cells.

  10. Evi1 is a key regulator of adipogenic competency

MDS1 and EVI1 Complex Locus (MECOM) Antigen-Profil

Beschreibung des Gens

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit MECOM

  • MDS1 and EVI1 complex locus (mecom) Antikörper
  • MDS1 and EVI1 complex locus (MECOM) Antikörper
  • MDS1 and EVI1 complex locus (LOC100343228) Antikörper
  • MDS1 and EVI1 complex locus (Mecom) Antikörper
  • runt-related transcription factor 1 (RUNX1) Antikörper
  • AML1 Antikörper
  • AML1-EVI-1 Antikörper
  • AMLCR1 Antikörper
  • CBFA2 Antikörper
  • D630039M04Rik Antikörper
  • EVI-1 Antikörper
  • Evi1 Antikörper
  • im:7140716 Antikörper
  • Jbo Antikörper
  • Mds Antikörper
  • Mds1 Antikörper
  • Mds1-Evi1 Antikörper
  • PEBP2aB Antikörper
  • Prdm3 Antikörper
  • Znfpr1b1 Antikörper

Bezeichner auf Proteinebene für MECOM

ecotropic viral integration site 1 , PR domain containing 3 , MDS1 and EVI1 complex locus , MDS1 and EVI1 complex locus protein EVI1-like , AML1-EVI-1 fusion protein , MDS1 and EVI1 complex locus protein EVI1 , MDS1 and EVI1 complex locus protein MDS1 , ecotropic virus integration site 1 protein homolog , myelodysplasia syndrome-associated protein 1 , oncogene EVI1 , zinc finger protein Evi1 , ecotropic virus integration site 1 protein , myelodysplasia syndrome 1 homolog , myelodysplasia syndrome 1 protein homolog , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core-binding factor, runt domain, alpha subunit 2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit

GENE ID SPEZIES
497407 Danio rerio
460837 Pan troglodytes
698603 Macaca mulatta
100343228 Oryctolagus cuniculus
100403987 Callithrix jacchus
100591579 Nomascus leucogenys
2122 Homo sapiens
14013 Mus musculus
424997 Gallus gallus
488148 Canis lupus familiaris
532209 Bos taurus
294924 Rattus norvegicus
861 Homo sapiens
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