You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-MDS1 and EVI1 Complex Locus (MECOM) Antikörper

The protein encoded by MECOM is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. Zusätzlich bieten wir Ihnen MDS1 and EVI1 Complex Locus Proteine (8) und MDS1 and EVI1 Complex Locus Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MECOM 2122 Q03112 , Q13465
MECOM 14013 Q9Z1L8
MECOM 294924  
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-MDS1 and EVI1 Complex Locus Antikörper auf antikoerper-online.de

Showing 10 out of 118 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-EVI1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Huhn Kaninchen Unkonjugiert WB WB Suggested Anti-EVI1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Huhn Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-EVI1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Lung 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of EVI1 Antibody (N-term) in CEM cell line lysates (35ug/lane). This demonstrates the EVI1 antibody detected the EVI1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-MDS1 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: Raji cell lysate WB Suggested Anti-MDS1  Antibody Titration: 1.25 µg/mL ELISA Titer: 1:312500  Positive Control: Raji cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of MDS1 Antibody (Center) in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the MDS1 antibody detected the MDS1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Ziege Unkonjugiert EIA, WB AP23733PU-N MECOM antibody staining of A549 lysate at 2 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: EVI1 Antibody [NBP1-68842] - Analysis of EVI1 in A549 lysate (35ug protein in RIPA buffer) using NBP1-68842 at 2ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
388,75 €
Details
Human Maus Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details

MECOM Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, ,
,
, , , , ,
Mouse (Murine)
,
,
, , , , ,
Rat (Rattus)


Am meisten referenzierte anti-MDS1 and EVI1 Complex Locus Antikörper

  1. Human Polyclonal MECOM Primary Antibody für EIA, WB - ABIN952135 : Gómez-Benito, Conchillo, García, Vázquez, Maicas, Vicente, Cristobal, Marcotegui, García-Ortí, Bandrés, Calasanz, Alonso, Odero: EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2. in British journal of cancer 2010 (PubMed)
    Zeige alle 2 Referenzen für ABIN952135

  2. Human Polyclonal MECOM Primary Antibody für EIA, WB - ABIN953364 : Goyama, Kurokawa: Evi-1 as a critical regulator of leukemic cells. in International journal of hematology 2010 (PubMed)
    Zeige alle 2 Referenzen für ABIN953364

  3. Human Polyclonal MECOM Primary Antibody für ELISA, WB - ABIN4270672 : Konrad, Karger, Hackl, Schwarzinger, Herbacek, Wieser: Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes. in Journal of leukocyte biology 2009 (PubMed)

  4. Chicken Polyclonal MECOM Primary Antibody für WB - ABIN2787657 : Sato, Goyama, Nitta, Takeshita, Yoshimi, Nakagawa, Kawazu, Ichikawa, Kurokawa: Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling. in Cancer science 2008 (PubMed)

  5. Human Polyclonal MECOM Primary Antibody für WB - ABIN2780631 : Fears, Mathieu, Zeleznik-Le, Huang, Rowley, Nucifora: Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)

  6. Chicken Polyclonal MECOM Primary Antibody für IHC, WB - ABIN2777403 : Chi, Senyuk, Chakraborty, Nucifora: EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity. in The Journal of biological chemistry 2003 (PubMed)

Weitere Antikörper gegen MDS1 and EVI1 Complex Locus Interaktionspartner

Zebrafish MDS1 and EVI1 Complex Locus (MECOM) Interaktionspartner

  1. nephrogenesis in zebrafish is regulated by interactions between retinoic acid, mecom, and Notch (zeige NOTCH1 Antikörper) signaling

  2. Prdm3 and prdm16 (zeige PRDM16 Antikörper) are strongly expressed in the pharyngeal arches during cranioskeletal development, and their knockdown leads to defects in both the viscerocranium and the neurocranium.

Human MDS1 and EVI1 Complex Locus (MECOM) Interaktionspartner

  1. the effects of various aberrations in ETV6 (zeige ETV6 Antikörper) and RUNX1 (zeige RUNX1 Antikörper) gene copy number on disease prognosis were evaluated in 21 pediatric patients diagnosed with B-cell ALL with/without t(12;21).

  2. The RUNX1 (zeige RUNX1 Antikörper) fusion transcript encodes a truncated protein containing the Runt (zeige RUNX1 Antikörper) homology domain responsible for both heterodimerization with CBFB (zeige CBFB Antikörper) and DNA binding, but lacking the proline-, serine-, and threonine-rich (PST (zeige SULT1A1 Antikörper)) region which is the transcription activation domain at the C terminal end

  3. novel RUNX1 (zeige RUNX1 Antikörper) isoforms contribute in controlling CD56 (zeige NCAM1 Antikörper) expression in acute myeloid leukemia (zeige BCL11A Antikörper) cells.

  4. this paper shows that RUNX1 (zeige RUNX1 Antikörper) is associated with the pathogenesis of immune thrombocytopenia possibly through regulation of Th17 cell differentiation

  5. We show that RUNX1 (zeige RUNX1 Antikörper) P1 expression is associated with colon cancer free survival suggesting a role for RUNX1 (zeige RUNX1 Antikörper) in aspirin's protective effect in colon cancer. Our studies reveal an effect of aspirin on RUNX1 (zeige RUNX1 Antikörper) and gene expression that may additionally explain aspirin's effects in cardiovascular disease and cancer.

  6. we identified rs2249650 and rs2268276 as new AML (zeige RUNX1 Antikörper) susceptibility-associated SNPs. Genome editing at rs2249650 and rs2268276 may be performed in future to uncover the effect of this potential RUNX1 (zeige RUNX1 Antikörper) enhancer region.

  7. RUNX1 (zeige RUNX1 Antikörper) and FKBP7 (zeige FKBP7 Antikörper), involved in erythropoesis and muscle protein synthesis, respectively, are related to change in cardiorespiratory fitness in response to exercise.

  8. HTLF (zeige FOXN2 Antikörper) is a RUNX1 (zeige RUNX1 Antikörper) target whose down-regulation promotes genomic instability and correlates with complex cytogenetic abnormalities in acute myeloid leukemia (zeige BCL11A Antikörper) patients.

  9. High RUNX1 (zeige RUNX1 Antikörper) expression is associated with breast cancer.

  10. The Leukemia Inhibitory Factor Receptor (zeige LIFR Antikörper) Gene Is a Direct Target of RUNX1 (zeige RUNX1 Antikörper)

Mouse (Murine) MDS1 and EVI1 Complex Locus (MECOM) Interaktionspartner

  1. the DNA sequences to which EVI1 binds at +35 and +37 kb and show that mutation of one of these releases Cebpa (zeige CEBPA Antikörper) from EVI1-induced suppression.

  2. Evi1(+)DA-3 cells modified to express an intracellular form of GM-CSF (zeige CSF2 Antikörper), acquired growth factor independence and transplantability and caused an overt leukemia in syngeneic hosts, without increasing serum GM-CSF (zeige CSF2 Antikörper) levels.

  3. Survivin (zeige BIRC5 Antikörper) partially regulates HSC (zeige FUT1 Antikörper) function by modulating the Evi-1 transcription factor and its downstream targets

  4. Thrombopoietin (zeige THPO Antikörper)/MPL (zeige MPL Antikörper) signaling confers growth and survival capacity to CD41-positive cells in a mouse model of Evi1 leukemia.

  5. Prdm16 (zeige PRDM16 Antikörper) and Prdm3 control postnatal BAT (zeige BAAT Antikörper) identity and function.

  6. Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

  7. PR-domain protein ME has an essential role in mixed-lineage leukemia (MLL (zeige MLL Antikörper)) fusion protein (MFP) leukemia

  8. Cotransduction of Evi1 and the shortest isoform of C/EBPbeta (zeige CEBPB Antikörper), liver inhibitory protein (LIP), induced acute myeloid leukemia (zeige BCL11A Antikörper) with short latencies in a mouse bone marow transplantation model.

  9. Transient Evi1 transfection inhibited TGF-beta-induced transcriptional activity and reversed the growth inhibitory effect of TGF-beta in MC-26 mouse colon cancer cells.

  10. Evi1 is a key regulator of adipogenic competency

MDS1 and EVI1 Complex Locus (MECOM) Antigen-Profil

Protein Überblick

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit MECOM

  • MDS1 and EVI1 complex locus (mecom) Antikörper
  • MDS1 and EVI1 complex locus (MECOM) Antikörper
  • MDS1 and EVI1 complex locus (LOC100343228) Antikörper
  • MDS1 and EVI1 complex locus (Mecom) Antikörper
  • runt-related transcription factor 1 (RUNX1) Antikörper
  • AML1 Antikörper
  • AML1-EVI-1 Antikörper
  • AMLCR1 Antikörper
  • CBFA2 Antikörper
  • D630039M04Rik Antikörper
  • EVI-1 Antikörper
  • Evi1 Antikörper
  • im:7140716 Antikörper
  • Jbo Antikörper
  • Mds Antikörper
  • Mds1 Antikörper
  • Mds1-Evi1 Antikörper
  • PEBP2aB Antikörper
  • Prdm3 Antikörper
  • Znfpr1b1 Antikörper

Bezeichner auf Proteinebene für MECOM

ecotropic viral integration site 1 , PR domain containing 3 , MDS1 and EVI1 complex locus , MDS1 and EVI1 complex locus protein EVI1-like , AML1-EVI-1 fusion protein , MDS1 and EVI1 complex locus protein EVI1 , MDS1 and EVI1 complex locus protein MDS1 , ecotropic virus integration site 1 protein homolog , myelodysplasia syndrome-associated protein 1 , oncogene EVI1 , zinc finger protein Evi1 , ecotropic virus integration site 1 protein , myelodysplasia syndrome 1 homolog , myelodysplasia syndrome 1 protein homolog , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core-binding factor, runt domain, alpha subunit 2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit

GENE ID SPEZIES
497407 Danio rerio
460837 Pan troglodytes
698603 Macaca mulatta
100343228 Oryctolagus cuniculus
100403987 Callithrix jacchus
100591579 Nomascus leucogenys
2122 Homo sapiens
14013 Mus musculus
424997 Gallus gallus
488148 Canis lupus familiaris
532209 Bos taurus
294924 Rattus norvegicus
861 Homo sapiens
Ausgewählte Anbieter für anti-MDS1 and EVI1 Complex Locus (MECOM) Antikörper
Haben Sie etwas anderes gesucht?