anti-Deoxyribonuclease I (DNASE1) Antikörper

DNASE1 encodes a member of the DNase family. Zusätzlich bieten wir Ihnen Deoxyribonuclease I Kits (63) und Deoxyribonuclease I Proteine (31) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DNASE1 1773 P24855
DNASE1 13419 P49183
DNASE1 25633 P21704
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Top anti-Deoxyribonuclease I Antikörper auf

Showing 10 out of 94 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-DNASE1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>PANC1 cell lysate WB Suggested Anti-DNASE1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: PANC1 cell lysate <br /> DNASE1 is supported by BioGPS gene expression data to be expressed in PANC1 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HT-29 cells, using DNL1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DNL1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC (p), WB Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: DNASE1 Antibody [NBP1-84999] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401601) Immunohistochemistry-Paraffin: DNASE1 Antibody [NBP1-84999] - Staining of human colon shows strong positivity in goblet cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image DNase I antibody [N1C3] detects DNase I protein at cytoplasm in human endometrial carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human endometrial carcinoma. DNase I antibody [N1C3] , diluted at 1:500. WB Image Sample (30 ug of whole cell lysate) A: MOLT4 , 10% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
Rind (Kuh) Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 1 bis 2 Tage
Rind (Kuh) Kaninchen Unkonjugiert EIA, WB   2 mL Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert WB Western Blot: DNASE1 Antibody [NBP1-59404] - Titration: 0.2-1 ug/ml, Positive Control: PANC1 cell lysate. Western Blot: DNASE1 Antibody [NBP1-59404] - Sample Tissue: Human Lung Tumor Antibody Dilution: 1.0 ug/ml 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert IF, IHC, WB Immunohistochemistry of paraffin-embedded mouse brain using DNASE1 antibody at dilution of 1:200 (400x lens). 100 μL Anmelden zum Anzeigen 16 Days

DNASE1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus) ,

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Am meisten referenzierte anti-Deoxyribonuclease I Antikörper

  1. Human Polyclonal DNASE1 Primary Antibody für IHC, IHC (p) - ABIN4305666 : Sonawane, Khanolkar, Namavari, Chaudhary, Gandhi, Tibrewal, Jassim, Shaheen, Hallak, Horner, Newcomb, Sarkar, Jain: Ocular surface extracellular DNA and nuclease activity imbalance: a new paradigm for inflammation in dry eye disease. in Investigative ophthalmology & visual science 2012 (PubMed)

Weitere Antikörper gegen Deoxyribonuclease I Interaktionspartner

Human Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. Serum DNase1-activity is significantly decreased in ALD (zeige ABCD1 Antikörper) patients, indicating its potential implication in their pathogenesis. Furthermore, DNase1-activity could be used as a new surrogate biomarker for predicting response to AIH treatment.

  2. Although no significant association between Q222R polymorphism in DNAse I gene and the risk of systemic lupus erythematosus was found, the presence of the A allele was associated with an increased risk for the development of nephropathy

  3. DNase I activity was observed to be increased in type 2 diabetes, and high glucose combined with increased DNase I is suggested to aggravate beta-cell apoptosis.

  4. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1, DNASE1L3 (zeige DNASE1L3 Antikörper), and DNASE2 (zeige DNASE2 Antikörper), possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  5. TNF-alpha (zeige TNF Antikörper) amplifies DNaseI expression in renal tubular cells while IL-1beta (zeige IL1B Antikörper) promotes nuclear DNaseI translocation in inactive form in lupus nephritis.

  6. HumDN1 polymorphisms were examined in blood of 11 worldwide populations by polymerase chain reaction. 15 genotypes were found leading to the conclusion that HumDN1 variable no. tandem repeats are ethnic group specific.

  7. Val66Met in the BDNF (zeige BDNF Antikörper) gene and two SNPs, Fokl and Apal, in the VDR (zeige CYP27B1 Antikörper) gene may potentially be associated with DED (zeige AATF Antikörper). Additionally, the association between DED (zeige AATF Antikörper) and Val66Met may vary by depression status.

  8. In conclusion, elevated DNase I in diabetes may be related to pancreatic injury and could be one of the causes that induce diabetes.

  9. Our results indicate that increased DNASE1 expression is common to both SLE and RA, while DNase1 reduction activity is specific to SLE.

  10. Characterization of the nonsynonymous single-nucleotide polymorphism variants of human DNASE1.

Mouse (Murine) Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. HMGN1 (zeige HMGN1 Antikörper) binds to CpG island-containing promoters and affects the organization of nucleosomes, DNase I hypersensitivity, and the transcriptional profile of mouse embryonic stem cells and neural progenitors.

  2. Early mesangial nephritis initiates a cascade of inflammatory signals that lead to up-regulation of Trap1 (zeige TRAP1 Antikörper) and a consequent down-regulation of renal DNaseI by transcriptional interference.

  3. silencing of renal DNaseI gene expression initiates a cascade of inflammatory signals including activation of Toll (zeige TLR4 Antikörper) like receptors and Clec4e (zeige CLEC4E Antikörper), leading to progression of both murine and human lupus nephritis

  4. Data show that deletion of DNaseI hypersensitive sites does not have an obvious impact on the IgH locus or B cell development.

  5. Reduction in renal Dnase1 expression and activity is limited to mice and SLE patients with signs of membranoproliferative nephritis, and may be a critical event in the development of severe forms of lupus nephritis.

  6. A conserved sequence located 211 kilobases upstream of class II major histocompatibility complex transcriptional coactivator (CIITA (zeige CIITA Antikörper)) promoter III is hypersensitive to DNase I.

  7. The impact of antibodies to dsDNA, renal Dnase1 and matrix metalloprotease (MMP) mRNA levels and enzyme activities on early and late events in murine lupus nephritis, was determined.

  8. serum Dnase1 in cooperation with the plasminogen (zeige PLG Antikörper) system guarantees a fast and effective breakdown of chromatin during necrosis by the combined cleavage of DNA as well as of DNA binding proteins.

  9. DNase I is essential for kidney injury induced by cisplatin

  10. Results describe chromatin disposal during necrosis and the involvement of Deoxyribonuclease 1 in this process with respect to its possible role in the prevention of anti-nuclear auto-immunity.

Cow (Bovine) Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. the practical capability of this assay system was successfully demonstrated by its use to determine DNase I activity in bovine urine.

  2. Specificity in DNA-DNase I interaction is mediated by DNA flexibility, which influences the induced-fit transitions required to form productive complexes.

Horse (Equine) Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. Purification and characterization of equine DNase 1 was done; it was confirmed to be of the parotid-type.

Deoxyribonuclease I (DNASE1) Antigen-Profil

Protein Überblick

This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Genbezeichner und Symbole assoziert mit DNASE1

  • DNase I (endA) Antikörper
  • DNase I (LOC397802) Antikörper
  • deoxyribonuclease 1 (DNASE1) Antikörper
  • deoxyribonuclease I (Dnase1) Antikörper
  • deoxyribonuclease 1 (Dnase1) Antikörper
  • deoxyribonuclease I L homeolog (dnase1.L) Antikörper
  • deoxyribonuclease I (dnase1) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011184) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011185) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011186) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011187) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011190) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ017803) Antikörper
  • Deoxyribonuclease I (Desal_1409) Antikörper
  • deoxyribonuclease I (MPET_RS05255) Antikörper
  • deoxyribonuclease I (METEV_RS02275) Antikörper
  • deoxyribonuclease I (Plabr_0631) Antikörper
  • AI788650 Antikörper
  • dnase1-A Antikörper
  • DNaseI Antikörper
  • Dnl1 Antikörper
  • DRNI Antikörper
  • LOC397802 Antikörper
  • zgc:92440 Antikörper

Bezeichner auf Proteinebene für DNASE1

DNase I , DNase I, lysosomal , Dornase alfa , deoxyribonuclease-1 , human urine deoxyribonuclease I , deoxyribonuclease I , Deoxyribonuclease I

8218482 Escherichia coli O157:H7 str. TW14359
397802 Xenopus laevis
1773 Homo sapiens
13419 Mus musculus
25633 Rattus norvegicus
282217 Bos taurus
394359 Xenopus laevis
395725 Gallus gallus
397051 Sus scrofa
403413 Canis lupus familiaris
436947 Danio rerio
6043536 Culex quinquefasciatus
6043537 Culex quinquefasciatus
6043538 Culex quinquefasciatus
6043539 Culex quinquefasciatus
6043542 Culex quinquefasciatus
6051839 Culex quinquefasciatus
8093039 Desulfovibrio salexigens DSM 2638
9743488 Methanoplanus petrolearius DSM 11571
100009513 Oryctolagus cuniculus
100034219 Equus caballus
9346074 Methanohalobium evestigatum Z-7303
10238020 Planctomyces brasiliensis DSM 5305
100718441 Cavia porcellus
101122154 Ovis aries
Ausgewählte Anbieter für anti-Deoxyribonuclease I (DNASE1) Antikörper
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