anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Antikörper

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Zusätzlich bieten wir Ihnen DNMT3B Kits (11) und DNMT3B Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DNMT3B 1789 Q9UBC3
DNMT3B 444985  
DNMT3B 13436 O88509
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Top anti-DNMT3B Antikörper auf antikoerper-online.de

Showing 10 out of 132 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-DNMT3B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: OVCAR-3 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: DNMT3B  Gene Name: Anonymous Submitted by: 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-Dnmt3b Pab (ABIN387884) in T47-D cell lysate. Dnmt3b (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded: human colon cancer tissue labeled with Anti-Dnmt-3-beta Polyclonal Antibody, Unconjugated (ABIN727623) at 1:600, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded: rat spinal cord tissue labeled with Anti-Dnmt-3-beta Polyclonal Antibody (ABIN727623), Unconjugated at 1:600, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from HT-29 cells, using DNMT3B Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using DNMT3B Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ChIP, IHC, IHC (p), SimWes, WB Immunohistochemistry-Paraffin: DNMT3B Antibody [ABIN152675] - Analysis showing positive staining in the nucleus and cytoplasm of Mouse brain tissue (right) compared with a negative control in the absence of primary antibody (left). Western Blot: DNMT3B Antibody [ABIN152675] - Homogenized mouse brain cells. Image from verified customer review. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Maus Unkonjugiert ChIP, CyTOF, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IHC (wm), IP, SimWes, WB Western blot analysis for Dnmt3b using ABIN252478 at 2 ug/ml against 10 µg of cell lysates of 293 transfected with mouse Dnmt3a (lane 1) and Dnmt3b (lane 2). A protein band of approximate mol. wt. of 110 kDa is only detected in 293 cells transfected with mouse Dnmt3b cDNA. Western blot analysis of Dnmt3b in NIH 3T3 cell lysate using ABIN252478 at 4 ug/ml. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
361,00 €
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
372,49 €
Details
Human Maus Unkonjugiert ChIP, WB DNMT3B mAb tested by Western blot. Detection of DNMT3B by Western blot. The analysis was performed using DNMT3B mAb at a 2 µg/ml dilution and whole-cell extracts from 293 cells that had been transfected with plasmid expressing either mouse DNMT3A (lane A) or DNMT3B (lane B). 100 μg Anmelden zum Anzeigen 1 bis 3 Tage
497,22 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IP, IHC, WB Western blot analysis using ABIN151734 to detect overexpressed DNMT-38 in HCT116 cells. Lane 1: 40 ug of nuclear extract from untransfected T24 cells. Lane 2-3: 40 ug of nuclear extracts transiently transfected to overexpress DNMT3B2 and DNMT3B3, respectively. Immunohistochemistry: Dnmt3b Antibody [ABIN151734] - Dnmt3b antibody was tested in mouse testis using DAB with hematoxylin counterstain. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details

DNMT3B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-DNMT3B Antikörper

  1. Human Monoclonal DNMT3B Primary Antibody für ChIP, CyTOF - ABIN252478 : Santoro, Li, Grummt: The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. in Nature genetics 2002 (PubMed)
    Zeige alle 97 Referenzen für 252478

  2. Human Polyclonal DNMT3B Primary Antibody für ICC, IF - ABIN151734 : Robert, Morin, Beaulieu, Gauthier, Chute, Barsalou, MacLeod: DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. in Nature genetics 2003 (PubMed)
    Zeige alle 16 Referenzen für 151734

  3. Human Polyclonal DNMT3B Primary Antibody für IHC (p), WB - ABIN387884 : Lu, Markowetz, Unwin, Leek, Airoldi, MacArthur, Lachmann, Rozov, Maayan, Boyer, Troyanskaya, Whetton, Lemischka: Systems-level dynamic analyses of fate change in murine embryonic stem cells. in Nature 2009 (PubMed)
    Zeige alle 13 Referenzen für 387884

  4. Human Polyclonal DNMT3B Primary Antibody für ChIP, IHC - ABIN152675 : Okano, Bell, Haber, Li: DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. in Cell 1999 (PubMed)
    Zeige alle 6 Referenzen für 152675

  5. Human Monoclonal DNMT3B Primary Antibody für ChIP, WB - ABIN2668954 : Castro, Breiling, Luetkenhaus, Ceteci, Hausmann, Kress, Lyko, Rudel, Rapp: MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma. in Molecular cancer research : MCR 2013 (PubMed)
    Zeige alle 2 Referenzen für 2668954

  6. Human Polyclonal DNMT3B Primary Antibody für IF (p), IHC (p) - ABIN727623 : Zhao, Hou, Chen, Shao, Zhu, Bu, Gu, Li, Zhang, Du, Fu, Kong, Luo, Long, Li, Deng, Zhao, Cen: Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation. in Neurobiology of disease 2015 (PubMed)
    Zeige alle 2 Referenzen für 727623

  7. Human Polyclonal DNMT3B Primary Antibody für IF, IHC - ABIN1534163 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  8. Human Polyclonal DNMT3B Primary Antibody für EIA, IHC (p) - ABIN356569 : Stipani, Cappello, Daddabbo, Natuzzi, Miniero, Stipani, Palmieri: The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents. in Biochemistry 2001 (PubMed)

  9. Cow (Bovine) Polyclonal DNMT3B Primary Antibody für WB - ABIN2783648 : Boland, Christman: Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA. in Journal of molecular biology 2008 (PubMed)

Weitere Antikörper gegen DNMT3B Interaktionspartner

Zebrafish DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. dnmt7 specifically methylates no tail gene in the genome

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation (zeige HELLS Antikörper) content are rather a function of time, and not a genetic component.

Human DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Overexpression of MAEL (zeige MAEL Antikörper) in UCB cells substantially enhanced the enrichment of DNA methyltrans-ferase (DNMT (zeige DNMT1 Antikörper))3B and histone deacetylase (HDAC)1 (zeige HDAC1 Antikörper)/2 on the promoter of the MTSS1 (zeige MTSS1 Antikörper), and thereby epigenetically suppressing the MTSS1 (zeige MTSS1 Antikörper) transcription.

  2. Data suggest that the overexpression of DNMT3B4 may play an important role in human kidney tumorigenesis through chromosomal instability and methylation of RASSF1A (zeige RASSF1 Antikörper).

  3. MUC1 (zeige MUC1 Antikörper)-C is of functional importance to induction of DNMT1 (zeige DNMT1 Antikörper) and DNMT3b and, in turn, changes in DNA methylation (zeige HELLS Antikörper) patterns in cancer cells.

  4. Dnmt3b plays a tumor suppressive role in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) AML (zeige RUNX1 Antikörper) progression

  5. Studies indicate that DNA methylation (zeige HELLS Antikörper) is mediated by three DNA (Cytosine-5-)-Methyltransferase (DNMTs): DNMT1 (zeige DNMT1 Antikörper) is responsible for the maintenance of methylation patterns after DNA replication whereas DNMT3A (zeige DNMT3A Antikörper) and DNMT3B carry out de novo methylation, and DNMT (zeige DNMT1 Antikörper) inhibitors have showed promising results in clinical trials of prostate cancer.

  6. novel functions for Dnmt3a (zeige DNMT3A Antikörper) and Dnmt3b at enhancers that could contribute to their roles in disease and tumorigenesis, are reported.

  7. in HCT116 colorectal cancer cells lacking DNA methyltransferases DNMT1 (zeige DNMT1 Antikörper) or DNMT3B, LCT13 expression decreases, while cells lacking both DNMTs or treated with the DNMT (zeige DNMT1 Antikörper) inhibitor 5-azacytidine (5-aza) show no change in LCT13 expression.

  8. In mammals, DNA methylation (zeige HELLS Antikörper) is introduced by the DNMT1 (zeige DNMT1 Antikörper), DNMT3A (zeige DNMT3A Antikörper), and DNMT3B enzymes, which are all large multi-domain proteins. These enzymes contain a catalytic C-terminal domain with a characteristic cytosine-C5 methyltransferase fold and an N-terminal part with different domains that interacts with other proteins and chromatin and is involved in targeting and regulation of the DNMTs

  9. data indicated that Kaempferol is a novel DNMT3B inhibitor, which may promote the degradation of DNMT3B in bladder cancer.

  10. TLR9 (zeige TLR9 Antikörper) upregulation in cases with episomal HPV16 was again higher among those with non-methylated immunostimulatory CpG motifs. Comparison of cases with HPV-negative controls revealed that DNMT3A (zeige DNMT3A Antikörper) was significantly downregulated only among integrated cases, DNMT3B was significantly overexpressed among both categories of cases, although at variable levels, while DNMT1 (zeige DNMT1 Antikörper) failed to show any deregulated expression among the cases

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. The epiblast expressed epithelial markers, MUC1 (zeige MUC1 Antikörper) and E-CADHERIN (zeige CDH1 Antikörper), and the pluripotency markers, DNMT3B and CRIPTO (zeige TDGF1 Antikörper).

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.

  2. The expression levels of DNMT3a (zeige DNMT3A Antikörper) and DNMT3b were associated with several beef quality traits.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. a new paradigm of transcriptional regulation critical for cardiac development and maturation that is controlled by the interaction of REST, DNMT3B and non-CpG methylation.

  2. Together, this study described the regulation of Chk2 (zeige CHEK2 Antikörper) expression through promoter methylation by Dnmt3b and also presented a novel role of Chk2 (zeige CHEK2 Antikörper) during neuronal differentiation, which is independent of its previously known function in DNA damage response.

  3. in mouse embryonic stem cells, Dnmt3b-dependent intragenic DNA methylation protects the gene body from spurious RNA polymerase II entry and cryptic transcription initiation

  4. three DNA methyltransferases, Dnmt1 (zeige DNMT1 Antikörper), Dnmt3a (zeige DNMT3A Antikörper), and Dnmt3b, have been identified. Dnmt3a (zeige DNMT3A Antikörper) and Dnmt3b are responsible for establishing DNA methylation (zeige HELLS Antikörper) patterns produced through their de novo-type DNA methylation (zeige HELLS Antikörper) activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l (zeige TRDMT1 Antikörper)), which is a member of the Dnmt3 family but does not possess DNA methylation (zeige HELLS Antikörper)

  5. While lens epithelial cell survival requires DNMT1 (zeige DNMT1 Antikörper), morphologically normal lenses develop in the absence of both DNMT3A (zeige DNMT3A Antikörper) and DNMT3B.

  6. Mechanical stimulation regulates osteoblastic genes expression via direct regulation of Dnmt3b.

  7. a miR (zeige MLXIP Antikörper)-125b-DNMT3b-p53 (zeige TP53 Antikörper) signal pathway may exist in the vascular smooth muscle cells proliferation induced by homocysteine.

  8. miR (zeige MLXIP Antikörper)-29a mimic transfection lowered collagen 1alpha1, DNMT1 (zeige DNMT1 Antikörper), DNMT3b and SET1A (zeige SETD1A Antikörper) expression in hepatic stellate cells.

  9. Loss of DNMT3B results in hypomethylation of the miR (zeige MLXIP Antikörper)-196b promoter and increased miR (zeige MLXIP Antikörper)-196b expression, which directly targets the mTORC2 (zeige CRTC2 Antikörper) component Rictor (zeige RICTOR Antikörper).

  10. The findings define PRMT7 (zeige PRMT7 Antikörper) as a regulator of the DNMT3b/p21 (zeige D4S234E Antikörper) axis required to maintain muscle stem cell regenerative capacity.

DNMT3B Antigen-Profil

Protein Überblick

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Genbezeichner und Symbole assoziert mit DNMT3B

  • DNA (cytosine-5-)-methyltransferase 4 (dnmt4) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3 beta (LOC100218113) Antikörper
  • DNA methyltransferase 3B (dnmt3b) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3 beta (dnmt3b) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3 beta (Dnmt3b) Antikörper
  • DNA methyltransferase 3B (Dnmt3b) Antikörper
  • cb91 Antikörper
  • cb633 Antikörper
  • DNMT3B Antikörper
  • dnmt3bl Antikörper
  • dnmt7 Antikörper
  • ICF Antikörper
  • ICF1 Antikörper
  • LOC100218113 Antikörper
  • M.HsaIIIB Antikörper
  • MmuIIIB Antikörper
  • sb:cb91 Antikörper
  • wu:fb16h07 Antikörper

Bezeichner auf Proteinebene für DNMT3B

DNA (cytosine-5)-methyltransferase 3B , DNA (cytosine-5-)-methyltransferase 3 beta , DNA cytosine-5 methyltransferase 3 beta , DNA (cytosine-5)-methyltransferase 3B-like , DNA methyl transferase beta , DNA methyltransferase 3B , DNA MTase HsaIIIB , DNA methyltransferase HsaIIIB , DNA (cytosine-5-)-methyltransferase 3 beta, like , DNA (cytosine-5-)-methyltransferase 7 , fb16h07 , DNA MTase MmuIIIB , DNA methyltransferase MmuIIIB

GENE ID SPEZIES
317744 Danio rerio
458174 Pan troglodytes
711553 Macaca mulatta
100053900 Equus caballus
100218113 Taeniopygia guttata
100412936 Callithrix jacchus
100459992 Pongo abelii
100466728 Ailuropoda melanoleuca
100500777 Ovis aries
100598378 Nomascus leucogenys
100528060 Anolis carolinensis
1789 Homo sapiens
321084 Danio rerio
419287 Gallus gallus
100302109 Sus scrofa
353354 Bos taurus
444985 Rattus norvegicus
13436 Mus musculus
Ausgewählte Anbieter für anti-DNMT3B (DNMT3B) Antikörper
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