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Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Zusätzlich bieten wir Ihnen PD-L1 Proteine (83) und PD-L1 Kits (47) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 359 products:
Human Monoclonal PD-L1 Primary Antibody für FACS, IHC (p) - ABIN1449244
Mandavilli: Hormone in the hot seat. in Nature medicine 2006
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Human Polyclonal PD-L1 Primary Antibody für EIA, WB - ABIN401427
Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004
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Human Polyclonal PD-L1 Primary Antibody für IHC, ELISA - ABIN185339
Thompson, Gillett, Cheville, Lohse, Dong, Webster, Krejci, Lobo, Sengupta, Chen, Zincke, Blute, Strome, Leibovich, Kwon: Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. in Proceedings of the National Academy of Sciences of the United States of America 2004
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Mouse (Murine) Monoclonal PD-L1 Primary Antibody für FACS - ABIN317020
Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003
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Human Monoclonal PD-L1 Primary Antibody für FACS - ABIN2853592
del Rio, Rodriguez-Barbosa, Kremmer, Förster: CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. in Journal of immunology (Baltimore, Md. : 1950) 2007
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Human Monoclonal PD-L1 Primary Antibody für FACS - ABIN1449174
Iwai, Okazaki, Nishimura, Kawasaki, Yagita, Honjo: Microanatomical localization of PD-1 in human tonsils. in Immunology letters 2002
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Human Monoclonal PD-L1 Primary Antibody für FACS, IHC - ABIN4899390
Rojas, Krishnan: IFN-gamma generates maturation-arrested dendritic cells that induce T cell hyporesponsiveness independent of Foxp3+ T-regulatory cell generation. in Immunology letters 2010
Human Monoclonal PD-L1 Primary Antibody für FACS - ABIN4896033
Nicolazzo, Raimondi, Mancini, Caponnetto, Gradilone, Gandini, Mastromartino, Del Bene, Prete, Longo, Cortesi, Gazzaniga: Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab. in Scientific reports 2016
findings indicate that the PerC (zeige PPARGC1B Antikörper) B cells, including PD-L1/PD-L2 (zeige PDCD1LG2 Antikörper) B-1a cells, may suppress T cells responding to allostimulation, and thus may be optimal for donor lymphocyte injection
PD-L1 selectively enhances T cell-mediated immune responses, driving graft-versus-host disease lethality and suggesting a context-dependent function of the PD-1 (zeige PDCD1 Antikörper)/PD-L1 axis
Mesenteric lymph node CD11b (zeige ITGAM Antikörper)(-) CD103 (zeige ITGAE Antikörper)(+) PD-L1(High) dendritic cell subset probably takes up luminal antigens in the intestine, migrates to MLNs, and highly induces regulatory T cells through TGF-beta (zeige TGFB1 Antikörper) activation.
These results indicate that the outcome of PD-L1-mediated signaling in CD8 (zeige CD8A Antikörper)+ T cells depends on the presence or absence of CD4 (zeige CD4 Antikörper)+ T cells, the nature of the interacting receptor expressed by CD8 (zeige CD8A Antikörper)+ T cells, and the tissue environment in which the signaling occurs.
CD169 (zeige SIGLEC1 Antikörper)(+) macrophages are important contributors to the IFN-I response and thereby influence antiviral activity, CD8 (zeige CD8A Antikörper)(+) T-cell exhaustion and immunopathology.
findings identify a previously unrecognized role of PD-L1 as an endogenous pain inhibitor and a neuromodulator.
reduced cytotoxicity as a key mechanism by which tumor PD-L1 suppresses antitumor immunity and demonstrate that tumor PD-L1 is not just a marker of suppressed antitumor immunity.
Apigenin inhibits IFN-gamma-induced (zeige SAMHD1 Antikörper) PD-L1 expression by breast cancer cells, potentially rendering BC cells that lack constitutive PD-L1 expression more susceptible to T cellmediated anti-tumor immune responses.
results reveal a novel CD40 (zeige CD40 Antikörper)-dependent regulation of PD-L1 trafficking induced upon TLR3 (zeige TLR3 Antikörper) signaling that dictates its inhibitory activity.
IL-6 (zeige IL6 Antikörper) and PD-L1 blockade combination inhibits hepatocellular carcinoma cancer development in a mouse model.
non-small cell lung cancer with KRAS mutations showed a trend for higher frequency of positive PD-L1 expression (meta-analysis).
PD-L1 in osteosarcoma patients mediated follicular helper T cells suppression.
Soft-tissue sarcoma patients with PD-L1 expression had worse overall survival compared with those without PD-L1 expression.
High PD-L1 expression is associated with head-and-neck squamous cell carcinoma.
PD-L1 underexpression is associated with Non-Small-Cell Lung Cancer.
High PD-L1 expression is associated with Non-Small-Cell Lung Cancer.
The meta-analysis indicated that positive expression of PD-L1 could serve as a good predictor for poor prognosis of Asian patients with HNC (zeige MMP8 Antikörper)
Results indicate that epidermal growth factor receptor(EGFR (zeige EGFR Antikörper))/programmed cell death 1 ligand 1 (PD-L1) pairs could separate the survival between EGFR (zeige EGFR Antikörper) low/PD-L1 positive and EGFR (zeige EGFR Antikörper) high/PD-L1 negative groups.
A previously unrecognized central role for MUC1 (zeige MUC1 Antikörper)-C in integrating PD-L1 activation with suppression of immune effectors and poor clinical outcome in non-small-cell lung cancer.
Studies indicate that positive PD-L1 expression was significantly correlated with KRAS mutation and EGFR (zeige EGFR Antikörper) mutation.
role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development
These data suggest that overexpression of PD-L1 and PD-L2 (zeige PDCD1LG2 Antikörper) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.
Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.
A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.
This study provides novel information for the understanding of signalling through PD-L1.
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
, CD274 antigen
, programmed cell death 1 ligand 1
, programmed cell death ligand 1
, B7 homolog 1
, PDCD1 ligand 1
, programmed death ligand 1