anti-CD274 Molecule (CD274) Antikörper

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Zusätzlich bieten wir Ihnen PD-L1 Proteine (83) und PD-L1 Kits (47) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CD274 60533 Q9EP73
CD274 29126 Q9NZQ7
CD274 499342  
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Top anti-PD-L1 Antikörper auf antikoerper-online.de

Showing 10 out of 359 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Ratte FITC FACS 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
297,00 €
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Human Maus Unkonjugiert FACS, IHC (p) 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Maus FITC FACS 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
418,00 €
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Human Maus PE FACS 50 Tests Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Maus Biotin FACS 1 mL Anmelden zum Anzeigen 7 bis 9 Tage
429,00 €
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Human Kaninchen Unkonjugiert EIA, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
440,00 €
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Human Maus PE FACS 25 Tests Anmelden zum Anzeigen 3 bis 4 Tage
180,00 €
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Human Maus Unkonjugiert FACS, IHC Detection of B7-H1/PD-L1 in Jurkat Human Cell Line by Flow Cytometry. B7-H1/PD-L1 in Human Colon Cancer. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
272,00 €
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Human Maus Unkonjugiert FACS 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
319,00 €
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185339 staining (0.3µg/ml) of Human Heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
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CD274 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PD-L1 Antikörper

  1. Human Monoclonal PD-L1 Primary Antibody für FACS, IHC (p) - ABIN1449244 : Mandavilli: Hormone in the hot seat. in Nature medicine 2006 (PubMed)
    Zeige alle 8 Referenzen für 1449244

  2. Human Polyclonal PD-L1 Primary Antibody für EIA, WB - ABIN401427 : Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004 (PubMed)
    Zeige alle 3 Referenzen für 401427

  3. Human Polyclonal PD-L1 Primary Antibody für IHC, ELISA - ABIN185339 : Thompson, Gillett, Cheville, Lohse, Dong, Webster, Krejci, Lobo, Sengupta, Chen, Zincke, Blute, Strome, Leibovich, Kwon: Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Zeige alle 2 Referenzen für 185339

  4. Mouse (Murine) Monoclonal PD-L1 Primary Antibody für FACS - ABIN317020 : Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Zeige alle 2 Referenzen für 317020

  5. Human Monoclonal PD-L1 Primary Antibody für FACS - ABIN2853592 : del Rio, Rodriguez-Barbosa, Kremmer, Förster: CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Zeige alle 2 Referenzen für 2853592

  6. Human Monoclonal PD-L1 Primary Antibody für FACS - ABIN1449174 : Iwai, Okazaki, Nishimura, Kawasaki, Yagita, Honjo: Microanatomical localization of PD-1 in human tonsils. in Immunology letters 2002 (PubMed)
    Zeige alle 2 Referenzen für 1449174

  7. Human Monoclonal PD-L1 Primary Antibody für FACS, IHC - ABIN4899390 : Rojas, Krishnan: IFN-gamma generates maturation-arrested dendritic cells that induce T cell hyporesponsiveness independent of Foxp3+ T-regulatory cell generation. in Immunology letters 2010 (PubMed)

  8. Human Monoclonal PD-L1 Primary Antibody für FACS - ABIN4896033 : Nicolazzo, Raimondi, Mancini, Caponnetto, Gradilone, Gandini, Mastromartino, Del Bene, Prete, Longo, Cortesi, Gazzaniga: Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab. in Scientific reports 2016 (PubMed)

Weitere Antikörper gegen PD-L1 Interaktionspartner

Mouse (Murine) CD274 Molecule (CD274) Interaktionspartner

  1. findings indicate that the PerC (zeige PPARGC1B Antikörper) B cells, including PD-L1/PD-L2 (zeige PDCD1LG2 Antikörper) B-1a cells, may suppress T cells responding to allostimulation, and thus may be optimal for donor lymphocyte injection

  2. PD-L1 selectively enhances T cell-mediated immune responses, driving graft-versus-host disease lethality and suggesting a context-dependent function of the PD-1 (zeige PDCD1 Antikörper)/PD-L1 axis

  3. Mesenteric lymph node CD11b (zeige ITGAM Antikörper)(-) CD103 (zeige ITGAE Antikörper)(+) PD-L1(High) dendritic cell subset probably takes up luminal antigens in the intestine, migrates to MLNs, and highly induces regulatory T cells through TGF-beta (zeige TGFB1 Antikörper) activation.

  4. These results indicate that the outcome of PD-L1-mediated signaling in CD8 (zeige CD8A Antikörper)+ T cells depends on the presence or absence of CD4 (zeige CD4 Antikörper)+ T cells, the nature of the interacting receptor expressed by CD8 (zeige CD8A Antikörper)+ T cells, and the tissue environment in which the signaling occurs.

  5. CD169 (zeige SIGLEC1 Antikörper)(+) macrophages are important contributors to the IFN-I response and thereby influence antiviral activity, CD8 (zeige CD8A Antikörper)(+) T-cell exhaustion and immunopathology.

  6. findings identify a previously unrecognized role of PD-L1 as an endogenous pain inhibitor and a neuromodulator.

  7. reduced cytotoxicity as a key mechanism by which tumor PD-L1 suppresses antitumor immunity and demonstrate that tumor PD-L1 is not just a marker of suppressed antitumor immunity.

  8. Apigenin inhibits IFN-gamma-induced (zeige SAMHD1 Antikörper) PD-L1 expression by breast cancer cells, potentially rendering BC cells that lack constitutive PD-L1 expression more susceptible to T cellmediated anti-tumor immune responses.

  9. results reveal a novel CD40 (zeige CD40 Antikörper)-dependent regulation of PD-L1 trafficking induced upon TLR3 (zeige TLR3 Antikörper) signaling that dictates its inhibitory activity.

  10. IL-6 (zeige IL6 Antikörper) and PD-L1 blockade combination inhibits hepatocellular carcinoma cancer development in a mouse model.

Human CD274 Molecule (CD274) Interaktionspartner

  1. non-small cell lung cancer with KRAS mutations showed a trend for higher frequency of positive PD-L1 expression (meta-analysis).

  2. PD-L1 in osteosarcoma patients mediated follicular helper T cells suppression.

  3. Soft-tissue sarcoma patients with PD-L1 expression had worse overall survival compared with those without PD-L1 expression.

  4. High PD-L1 expression is associated with head-and-neck squamous cell carcinoma.

  5. PD-L1 underexpression is associated with Non-Small-Cell Lung Cancer.

  6. High PD-L1 expression is associated with Non-Small-Cell Lung Cancer.

  7. The meta-analysis indicated that positive expression of PD-L1 could serve as a good predictor for poor prognosis of Asian patients with HNC (zeige MMP8 Antikörper)

  8. Results indicate that epidermal growth factor receptor(EGFR (zeige EGFR Antikörper))/programmed cell death 1 ligand 1 (PD-L1) pairs could separate the survival between EGFR (zeige EGFR Antikörper) low/PD-L1 positive and EGFR (zeige EGFR Antikörper) high/PD-L1 negative groups.

  9. A previously unrecognized central role for MUC1 (zeige MUC1 Antikörper)-C in integrating PD-L1 activation with suppression of immune effectors and poor clinical outcome in non-small-cell lung cancer.

  10. Studies indicate that positive PD-L1 expression was significantly correlated with KRAS mutation and EGFR (zeige EGFR Antikörper) mutation.

Pig (Porcine) CD274 Molecule (CD274) Interaktionspartner

  1. role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development

  2. These data suggest that overexpression of PD-L1 and PD-L2 (zeige PDCD1LG2 Antikörper) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.

  3. Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.

  4. A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.

Cow (Bovine) CD274 Molecule (CD274) Interaktionspartner

  1. This study provides novel information for the understanding of signalling through PD-L1.

PD-L1 (CD274) Antigen-Profil

Protein Überblick

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Genbezeichner und Symbole assoziert mit anti-CD274 Molecule (CD274) Antikörper

  • CD274 molecule (CD274) Antikörper
  • CD274 molecule (LOC100357106) Antikörper
  • CD274 antigen (Cd274) Antikörper
  • CD274 molecule (Cd274) Antikörper
  • programmed cell death 1 ligand 2 (PDCD1LG2) Antikörper
  • A530045L16Rik Antikörper
  • B7-H Antikörper
  • B7H1 Antikörper
  • PD-L1 Antikörper
  • PDCD1L1 Antikörper
  • PDCD1LG1 Antikörper
  • PDL1 Antikörper
  • RGD1566211 Antikörper

Bezeichner auf Proteinebene für anti-CD274 Molecule (CD274) Antikörper

CD274 molecule , CD274 antigen , programmed cell death 1 ligand 1 , programmed cell death ligand 1 , B7 homolog 1 , PDCD1 ligand 1 , programmed death ligand 1

GENE ID SPEZIES
427224 Gallus gallus
464981 Pan troglodytes
716043 Macaca mulatta
100126721 Papio anubis
100357106 Oryctolagus cuniculus
60533 Mus musculus
29126 Homo sapiens
499342 Rattus norvegicus
100722088 Cavia porcellus
574058 Sus scrofa
484186 Canis lupus familiaris
533834 Bos taurus
427225 Gallus gallus
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