anti-CD274 Molecule (CD274) Antikörper

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Zusätzlich bieten wir Ihnen PD-L1 Proteine (83) und PD-L1 Kits (52) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CD274 60533 Q9EP73
CD274 29126 Q9NZQ7
CD274 499342  
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Top anti-PD-L1 Antikörper auf antikoerper-online.de

Showing 10 out of 402 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, FACS, ICC, IF, IHC, IHC (p), WB Flow Cytometry: B7-H1/PD-L1/CD274 Antibody [NBP1-76769] - Analysis of A-20 cells using B7-H1/PD-L1/CD274 antibody at 0.5 ug/ml. Green: Isotype control. Red : B7-H1/PD-L1/CD274 antibody. Immunohistochemistry: B7-H1/PD-L1/CD274 Antibody [NBP1-76769] - Staining of human heart tissue with antibody at 2.5 ug/mL. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$538.13
Details
Human Maus Unkonjugiert FACS, IHC (p) 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Human Maus FITC FACS 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Maus Ratte FITC FACS 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$434.50
Details
Human Maus Unkonjugiert CyTOF, FACS, IHC Detection of B7-H1/PD-L1 in Jurkat Human Cell Line by Flow Cytometry. B7-H1/PD-L1 in Human Colon Cancer. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$285.60
Details
Human Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Immunohistochemistry-Paraffin: B7-H1/PD-L1/CD274 Antibody [ABIN268676] - B7-H1/PD-L1/CD274 (4ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Immunohistochemistry: B7-H1/PD-L1/CD274 Antibody [ABIN268676] - Staining of Human Skeletal Muscle. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Maus Ziege Unkonjugiert CyTOF, FACS, IHC, WB Detection of Mouse B7-H1/PD-L1 by Western Blot. Western blot shows lysates of RAW 264.7 mouse monocyte/macrophage cell line untreated (-) or treated (+) with 10 ug/mL LPS for 4 hours. PVDF membrane was probed with 0.5 ug/mL of Goat Anti-Mouse B7-H1/PD-L1 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. Detection of B7-H1/PD-L1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line either treated with LPS overnight (filled histogram) or untreated (open histogram) was stained with Goat Anti-Mouse B7-H1/PD-L1 Antigen Affinity-purified Polyclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$388.50
Details
Human Kaninchen Unkonjugiert WB Anti-PD-L1 Picoband antibody,  All lanes: Anti PDL1  at 0.5ug/ml WB: HEPG2 Whole Cell Lysate at 40ug Predicted bind size: 33KD Observed bind size: 33KD Anti-PD-L1 Picoband antibody,  All lanes: Anti PDL1  at 0.5ug/ml WB: Recombinant Human PDL1 Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Maus PE FACS 50 Tests Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details

CD274 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PD-L1 Antikörper

  1. Mouse (Murine) Polyclonal PD-L1 Primary Antibody für CyTOF, FACS - ABIN4899388 : Wang, Yoshida, Nakaki, Hiai, Okazaki, Honjo: Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal PD-L1 Primary Antibody für FACS, IHC (p) - ABIN1449244 : Mandavilli: Hormone in the hot seat. in Nature medicine 2006 (PubMed)
    Show all 8 Pubmed References

  3. Human Polyclonal PD-L1 Primary Antibody für IHC, ELISA - ABIN1002984 : Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal PD-L1 Primary Antibody für IHC (p), ELISA - ABIN1995635 : Soliman, Khalil, Antonia: PD-L1 expression is increased in a subset of basal type breast cancer cells. in PLoS ONE 2014 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal PD-L1 Primary Antibody für IHC (p), WB - ABIN2479616 : Ishida, Agata, Shibahara, Honjo: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. in The EMBO journal 1992 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal PD-L1 Primary Antibody für ELISA, FACS - ABIN4282770 : Aguilar, Shirley, Chung, Marsh, Walker, Coyle, Marx, Bekaii-Saab, Lesinski, Swanson, Sanchez, Manzanera, Aguilar-Cordova, Bloomston: Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma. in Cancer immunology, immunotherapy : CII 2015 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal PD-L1 Primary Antibody für IHC, ELISA - ABIN1031034 : Angell, Lechner, Jang, Correa, LoPresti, Epstein: BRAF(V600E) in Papillary Thyroid Carcinoma is Associated with Increased Programmed Death Ligand 1 Expression and Suppressive Immune Cell Infiltration. in Thyroid : official journal of the American Thyroid Association 2014 (PubMed)

  8. Human Polyclonal PD-L1 Primary Antibody für ELISA, IHC - ABIN268676 : Thompson, Gillett, Cheville, Lohse, Dong, Webster, Krejci, Lobo, Sengupta, Chen, Zincke, Blute, Strome, Leibovich, Kwon: Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)

  9. Human Polyclonal PD-L1 Primary Antibody für IHC, ELISA - ABIN185339 : Chen, Li, Meng, Fan, Song, Wang, Zhu, Guo, Zhang, Shi: Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas. in Cancer immunology, immunotherapy : CII 2012 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal PD-L1 Primary Antibody für FACS - ABIN2479611 : Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)

Weitere Antikörper gegen PD-L1 Interaktionspartner

Mouse (Murine) CD274 Molecule (CD274) Interaktionspartner

  1. It was concluded that down-regulated expression of miR (zeige MLXIP Antikörper)-143 and up-regulation of its direct target B7H1 may indicate a novel therapeutic method for radiation-induced thymic lymphoma by increased expression of miR (zeige MLXIP Antikörper)-143 or inhibition of B7H1.

  2. HDAC6 (zeige HDAC6 Antikörper) inhibition reduces tumor growth and PD-L1 production in vivo.

  3. findings indicate that the PerC (zeige PPARGC1B Antikörper) B cells, including PD-L1/PD-L2 (zeige PDCD1LG2 Antikörper) B-1a cells, may suppress T cells responding to allostimulation, and thus may be optimal for donor lymphocyte injection

  4. PD-L1 selectively enhances T cell-mediated immune responses, driving graft-versus-host disease lethality and suggesting a context-dependent function of the PD-1 (zeige PDCD1 Antikörper)/PD-L1 axis

  5. Mesenteric lymph node CD11b (zeige ITGAM Antikörper)(-) CD103 (zeige ITGAE Antikörper)(+) PD-L1(High) dendritic cell subset probably takes up luminal antigens in the intestine, migrates to MLNs, and highly induces regulatory T cells through TGF-beta (zeige TGFB1 Antikörper) activation.

  6. These results indicate that the outcome of PD-L1-mediated signaling in CD8 (zeige CD8A Antikörper)+ T cells depends on the presence or absence of CD4 (zeige CD4 Antikörper)+ T cells, the nature of the interacting receptor expressed by CD8 (zeige CD8A Antikörper)+ T cells, and the tissue environment in which the signaling occurs.

  7. CD169 (zeige SIGLEC1 Antikörper)(+) macrophages are important contributors to the IFN-I response and thereby influence antiviral activity, CD8 (zeige CD8A Antikörper)(+) T-cell exhaustion and immunopathology.

  8. findings identify a previously unrecognized role of PD-L1 as an endogenous pain inhibitor and a neuromodulator.

  9. reduced cytotoxicity as a key mechanism by which tumor PD-L1 suppresses antitumor immunity and demonstrate that tumor PD-L1 is not just a marker of suppressed antitumor immunity.

  10. Apigenin inhibits IFN-gamma-induced (zeige SAMHD1 Antikörper) PD-L1 expression by breast cancer cells, potentially rendering BC cells that lack constitutive PD-L1 expression more susceptible to T cellmediated anti-tumor immune responses.

Human CD274 Molecule (CD274) Interaktionspartner

  1. CD38, BCL-2 (zeige BCL2 Antikörper), PD-1 (zeige PDCD1 Antikörper), and PD-1L expression in nodal peripheral T-cell lymphoma

  2. All structural variations invariably result in a prominent increase of aberrant PD-L1 transcripts commonly lacking an intact 3'-UTR (zeige UTS2R Antikörper), which most typically generate gene fusions with ectopic sequences including integrated viral genomes[review]

  3. Both subtypes demonstrate PD-L1(+) immune cells with tumor-infiltrating patterns, unlike the more commonly seen PD-L1(+) immune cells at the invasive margin.

  4. Immune checkpoint blockade with agents targeting the PD-1 (zeige PDCD1 Antikörper)/PD-L1 pathway has shown antitumor activity in two clinical trials for advanced Merkel cell carcinoma. There is also promise for immune checkpoint blockade in combination with radiotherapy and other treatments for advanced Merkel cell carcinoma

  5. Studies show that patients with PD-L1 positive tumors had a significantly higher Overall Response Rate (ORR) compared to patients with PD-L1 negative tumors.

  6. PD-L1 expression positively correlated LMP1 (zeige PDLIM7 Antikörper) expression in NKTCL, which was probably mediated by the MAPK (zeige MAPK1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) pathway. PD-L1 expression in serum and tumor tissues has significant prognostic value for early-stage NKTCL

  7. Ewing sarcoma cells can upregulate PD-L1 under inflammatory conditions, but do not express the ligand in the pretherapeutic tumor microenvironment or postexposure to CAR T cells.

  8. Findings indicated that BIN1 (zeige BIN1 Antikörper) restoration in NSCLC could reverse PD-L1-mediated immune escape by inactivating the c-MYC (zeige MYC Antikörper) and EGFR (zeige EGFR Antikörper)/mitogen-activated protein kinase (zeige MAPK1 Antikörper) pathways.

  9. review PD-L1 expression, PD-L1-mediated immunosuppressive mechanisms, and the clinical applications of PD-1 (zeige PDCD1 Antikörper)/PD-L1 inhibitors in gliomas.

  10. We investigated tumor-infiltrating CD4 (zeige CD4 Antikörper) and CD8 (zeige CD8A Antikörper) T cells and the expression of PD-L1, Galectin-9 (zeige LGALS9 Antikörper), and XAGE1 (zeige XAGE1A Antikörper) in stage I to IIIA lung adenocarcinomas using a tissue microarray to deduce their contribution to overall survival, and our data showed that PD-L1 expression was a positive indicator, whereas Galectin-9 (zeige LGALS9 Antikörper) and XAGE1 (zeige XAGE1A Antikörper) expression was negative.

Pig (Porcine) CD274 Molecule (CD274) Interaktionspartner

  1. These results suggest that the soluble recombinant proteins may be used to prepare monoclonal antibodies to block the PD-1 (zeige PDCD1 Antikörper)/PD-L1 pathway.

  2. role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development

  3. These data suggest that overexpression of PD-L1 and PD-L2 (zeige PDCD1LG2 Antikörper) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.

  4. Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.

  5. A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.

Cow (Bovine) CD274 Molecule (CD274) Interaktionspartner

  1. This study provides novel information for the understanding of signalling through PD-L1.

PD-L1 (CD274) Antigen-Profil

Protein Überblick

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Genbezeichner und Symbole assoziert mit anti-CD274 Molecule (CD274) Antikörper

  • CD274 molecule (CD274) Antikörper
  • CD274 antigen (Cd274) Antikörper
  • CD274 molecule (Cd274) Antikörper
  • programmed cell death 1 ligand 2 (PDCD1LG2) Antikörper
  • A530045L16Rik Antikörper
  • B7-H Antikörper
  • B7H1 Antikörper
  • PD-L1 Antikörper
  • PDCD1L1 Antikörper
  • PDCD1LG1 Antikörper
  • PDL1 Antikörper
  • RGD1566211 Antikörper

Bezeichner auf Proteinebene für anti-CD274 Molecule (CD274) Antikörper

CD274 molecule , CD274 antigen , programmed cell death 1 ligand 1 , programmed cell death ligand 1 , B7 homolog 1 , PDCD1 ligand 1 , programmed death ligand 1

GENE ID SPEZIES
427224 Gallus gallus
464981 Pan troglodytes
716043 Macaca mulatta
100126721 Papio anubis
100357106 Oryctolagus cuniculus
60533 Mus musculus
29126 Homo sapiens
499342 Rattus norvegicus
100722088 Cavia porcellus
574058 Sus scrofa
484186 Canis lupus familiaris
533834 Bos taurus
427225 Gallus gallus
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