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The protein encoded by BMF belongs to the BCL2 protein family. Zusätzlich bieten wir Ihnen BMF Kits (26) und BMF Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 119 products:
Human Polyclonal BMF Primary Antibody für IHC, WB - ABIN411435
Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. in Blood 2007
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Human Polyclonal BMF Primary Antibody für WB - ABIN2477675
Puthalakath, Villunger, OReilly, Beaumont, Coultas, Cheney, Huang, Strasser: Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. in Science (New York, N.Y.) 2001
Human Polyclonal BMF Primary Antibody für ICC, IF - ABIN4284847
Gramantieri, Fornari, Ferracin, Veronese, Sabbioni, Calin, Grazi, Croce, Bolondi, Negrini: MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Reciprocal regulation of BMF and BIRC5 (zeige BIRC5 Antikörper) is linked to Eomes (zeige EOMES Antikörper) overexpression in colorectal cancer.
Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc (zeige MYC Antikörper) and low Bmf expression
these findings suggest that p53 (zeige TP53 Antikörper)-R273H can specifically drive AKT (zeige AKT1 Antikörper) signaling and suppress BMF expression, resulting in enhanced cell survivability and anoikis resistance.
On the corresponding BMF gene promoter, loss of HDAC8 (zeige HDAC8 Antikörper) was associated with signal transducer and activator of transcription 3 (STAT3 (zeige STAT3 Antikörper))/specificity protein 3 (Sp3) transcription factor exchange and recruitment of p300 (zeige EP300 Antikörper).
Overexpression of ApoL2 (zeige APOL2 Antikörper) did not induce cell death on its own. ApoL2 (zeige APOL2 Antikörper) did not sensitize or protect cells from overexpression of the BH3-only (zeige BBC3 Antikörper) proteins Bmf or Noxa (zeige PMAIP1 Antikörper).
Diva (zeige BCL2L10 Antikörper) binds peptides derived from the BH3 domain of several other proapoptotic Bcl-2 (zeige BCL2 Antikörper) proteins, including mouse Harakiri (zeige HRK Antikörper), Bid (zeige BID Antikörper), Bak (zeige BAK1 Antikörper) and Bmf.
BMF is induced in human IEC by the loss of cell attachment and is likely to play an important role in the regulation of IEC survival
characterization of the bmf gene locus; molecular basis of the generation of the 2 major isoforms of Bmf; provide evidence that Bmf can act as a sensor for stress that associates with the repression of the conventional CAP-dependent translation machinery
Data show that hypoxic conditions inhibit anoikis and block expression of proapoptotic BH3-only (zeige BBC3 Antikörper) family members Bim (zeige BCL2L11 Antikörper) and Bmf in epithelial cells.
Bmf is upregulated by PS-341 and has a crucial role in PS-341-mediated glioma cell death through JNK (zeige MAPK8 Antikörper) phosphorylation.
BMF loss is associated with germ cell loss during oogenesis.
Bcl2 interacting mediator of cell death (Bim (zeige BCL2L11 Antikörper)) and Bcl2 modifying factor (Bmf), mediate apoptosis in the context of TACI (zeige TNFRSF13B Antikörper)-Ig overexpression that effectively neutralizes BAFF (zeige TNFSF13B Antikörper) as well as APRIL.
Bmf deficiency induced significant protection against oxygen/glucose deprivation injury in cultured neurons.
Our findings support an important role for BMF in determining the number of primordial follicles maintained in the ovary throughout adult reproductive life.
Bim (zeige BCL2L11 Antikörper) and Bmf act in concert to prevent autoimmunity and malignant disease
Bmf-deficient mice showed normal sensitivity to the convulsant effects of KA, displayed significantly more neuronal death in the hippocampal CA1 (zeige CA1 Antikörper) and CA3 (zeige CA3 Antikörper) subfields after SE.
deacetylation of p53 (zeige TP53 Antikörper) suppresses Bmf expression and facilitates autophagy.
critical role for Bim (zeige BCL2L11 Antikörper) and Bmf as regulators of hematopoietic stem and progenitor cell dynamics both during early engraftment and long-term reconstitution
our study suggests that Bad and Bmf co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.
a potential role for Bmf in regulating renal proximal tubular cells (RPTC) apoptosis and tubular atrophy in diabetes.
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Bcl2 modifying factor
, bcl-2-modifying factor
, Bcl-2 modifying factor
, Bcl-2-modifying factor