anti-SKP1 (SKP1) Antikörper

Bezeichnung:
anti-S-Phase Kinase-Associated Protein 1 Antikörper (SKP1)
Auf www.antikoerper-online.de finden Sie aktuell 121 S-Phase Kinase-Associated Protein 1 (SKP1) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SKP1 Proteine (25) und SKP1 Kits (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 167 SKP1 Produkte verfügbar.
Synonyme:
15kDa, 2610043E24Rik, 2610206H23Rik, ARABIDOPSIS SKP1 HOMOLOGUE 1, ASK1, ATSKP1, EMC19, ocp-2, OCP-II, OCP2, p19A, p19Skp1, SKP1, Skp1a, S phase kinase-associated protein 1, T4O12.17, T4O12_17, Tceb1l, UFO INTERACTING PROTEIN 1, UIP1, zgc:73186

Meistgesuchte Reaktivitäten zu anti-SKP1 (SKP1) Antikörper

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anti-Human SKP1 Antikörper:

anti-Rat (Rattus) SKP1 Antikörper:

anti-Mouse (Murine) SKP1 Antikörper:

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Am meisten referenzierte anti-SKP1 Antikörper

  1. Human Polyclonal SKP1 Primary Antibody für EIA, IP - ABIN117959 : Wang, He, Wang, Wang, Zhai, Zhou, Zhang, Zhai, Feng, Han: [Impact of Donor KIR2DS5 Genotype on Outcome Following Haploidentical Hematopoietic Stem Cell Transplantation.] in Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2008 (PubMed)
    Zeige alle 13 Referenzen für 117959

  2. Human Polyclonal SKP1 Primary Antibody für EIA, WB - ABIN357264 : Wu, Xu, Schulman, Jeffrey, Harper, Pavletich: Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. in Molecular cell 2003 (PubMed)
    Zeige alle 5 Referenzen für 357264

  3. Human Monoclonal SKP1 Primary Antibody für IF, WB - ABIN393543 : Davies, Kaplan: Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. in The Journal of cell biology 2010 (PubMed)
    Zeige alle 5 Referenzen für 393543

  4. Chicken Monoclonal SKP1 Primary Antibody für BI, IP - ABIN968019 : Carrano, Pagano: Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression. in The Journal of cell biology 2001 (PubMed)
    Zeige alle 4 Referenzen für 968019

  5. Human Monoclonal SKP1 Primary Antibody für ICC, FACS - ABIN969397 : Werden, Lanchbury, Shattuck, Neff, Dufford, McFadden: The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells. in Journal of virology 2009 (PubMed)

  6. Human Monoclonal SKP1 Primary Antibody für FACS, IHC - ABIN969398 : Plesca, Mazumder, Gama, Matsuyama, Almasan: A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron. in The Journal of biological chemistry 2008 (PubMed)

  7. Human Polyclonal SKP1 Primary Antibody für IP, WB - ABIN233777 : Shiraishi, Zhou, Aoki, Sato, Chiba, Tanaka, Yoshida, Nabeshima, Nabeshima, Tamura: TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation. in The Journal of biological chemistry 2007 (PubMed)

Weitere Antikörper gegen SKP1 Interaktionspartner

Human S-Phase Kinase-Associated Protein 1 (SKP1) Interaktionspartner

  1. Segregation analysis revealed that variants c.475T>G in SKP1, c.671G>A in PROB1, and c.527G>A in IL17B in the 5q31.1-q35.3 linkage region, and c.850G>A in HKDC1 in the 10q22 locus completely segregated with the phenotype in the studied Keratoconus family

  2. Both the F-box domain of Skp2 and Skp1-Skp2 domain motions displaying preferential conformational control can together facilitate polyubiquitination of a wide variety of substrates.

  3. Skp1 is critical to lung cancer pathogenesis

  4. Data show that epithelial-mesenchymal transition (EMT (zeige ITK Antikörper))-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1-Pam (zeige PAM Antikörper)-Fbxo45 (zeige FBXO45 Antikörper) (SPFFbxo45).

  5. We discuss how these results can explain the rapid association of Cdc34 (zeige CDC34 Antikörper) and Skp1-cullin-F-box ligase (SCF (zeige KITLG Antikörper)).

  6. SKP1 variation modifies association between Parkinson's disease and ubiquitin-proteasome system-inhibiting pesticides

  7. Studies indicate that in SCFs, Rbx1 serves as the RING-containing enzyme, Cul1 (zeige CUL1 Antikörper) is the Cullin scaffold, and Skp1 is an adaptor, which serves to link the beta-TrCP (zeige BTRC Antikörper) F-box substrate-specific factor to the rest of the ligase.

  8. Substrate binding promotes formation of the Skp1-Cul1 (zeige CUL1 Antikörper)-Fbxl3 (zeige FBXL3 Antikörper) (SCF (zeige KITLG Antikörper)(Fbxl3 (zeige FBXL3 Antikörper))) protein complex.

  9. Skp1-Cul1 (zeige CUL1 Antikörper)-F-box ubiquitin ligase (SCF (zeige KITLG Antikörper)(betaTrCP (zeige BTRC Antikörper)))-mediated destruction of the ubiquitin-specific protease USP37 (zeige USP37 Antikörper) during G2-phase promotes mitotic entry

  10. Deconjugation of Nedd8 (zeige NEDD8 Antikörper) from Cul1 (zeige CUL1 Antikörper) is directly regulated by Skp1-F-box and substrate, and the COP9 (zeige COPS8 Antikörper) signalosome inhibits deneddylated SCF (zeige KITLG Antikörper) by a noncatalytic mechanism.

Cow (Bovine) S-Phase Kinase-Associated Protein 1 (SKP1) Interaktionspartner

  1. The SCF (zeige KITLG Antikörper)-complex gene expression has been characterized during bovine preimplantation development (zeige MTA2 Antikörper).

Arabidopsis thaliana S-Phase Kinase-Associated Protein 1 (SKP1) Interaktionspartner

  1. How ASK1 might regulate protein stability and further downstream gene expression

  2. ABA induced the phosphorylation of three basic helix-loop-helix (bHLH) transcription factors, called AKSs (ABA-responsive kinase substrates; AKS1, AKS2, and AKS3), in Arabidopsis guard cells

  3. ASK1 and ASK2, are required for Agrobacterium-mediated plant transformation.

  4. ASK1 or ASK2 overexpression could rescue or partially rescue the Abscisic acid (ABA)insensitivity of abi5 (zeige ABI5 Antikörper)-1 mutants, respectively.

  5. ASK1 is predominately expressed from leptotene to pachytene, and negatively regulates recombination in Arabidopsis.

  6. Through the ASK1-mediated proteolysis pathway, ASK1 proteins showed pleiotropic functions including photomorphogenesis, circadian oscillation, post-translation process, stress-responses and cell expansion or elongation.

  7. ASK1 is required for normal SYN1 distribution during meiotic prophase I and suggest that ask1 associated defects may be primarily related to SYN1 mislocalization.

  8. These results raise the interesting possibility that ASK1 controls chromatin structure by targeting of either an early regulator of meiotic progression or possibly matrix attachment proteins for destruction.

Mouse (Murine) S-Phase Kinase-Associated Protein 1 (SKP1) Interaktionspartner

  1. Lysine 29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.

  2. Substrate binding promotes formation of the Skp1-Cul1 (zeige CUL1 Antikörper)-Fbxl3 (zeige FBXL3 Antikörper) (SCF (zeige KITLG Antikörper)(Fbxl3 (zeige FBXL3 Antikörper))) protein complex.

  3. In this review, deficiency of SKP1A in SN4741 cells closely recapitulates cardinal (zeige CARD8 Antikörper) features of the dopamine (DA) neuron pathology of human Parkinson's disease, such as decreased expression of DA phenotypic markers and cell cycle aberrations.

  4. phosphorylated NIPA (zeige ZC3HC1 Antikörper) is degraded in late mitosis in an APC (zeige APC Antikörper)/C(Cdh1 (zeige CDH1 Antikörper))-dependent manner

  5. Skp1 is a potential modifier in sporadic Parkinson disease neurodegeneration

Guinea Pig S-Phase Kinase-Associated Protein 1 (SKP1) Interaktionspartner

  1. study evaluated the conformational stabilities of OCP1 (zeige FBXO2 Antikörper) and OCP2

SKP1 Antigen-Profil

Beschreibung des Gens

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Alternative names and synonyms associated with SKP1

  • S-phase kinase-associated protein 1 (skp1) Antikörper
  • S-phase kinase-associated protein 1 (SKP1) Antikörper
  • S-phase kinase-associated protein 1 (LOC100340043) Antikörper
  • S-phase kinase-associated protein 1 (Skp1) Antikörper
  • S-phase kinase-associated protein 1A (Skp1a) Antikörper
  • S-phase kinase-associated protein 1A (Skp1) Antikörper
  • 15kDa Antikörper
  • 2610043E24Rik Antikörper
  • 2610206H23Rik Antikörper
  • ARABIDOPSIS SKP1 HOMOLOGUE 1 Antikörper
  • ASK1 Antikörper
  • ATSKP1 Antikörper
  • EMC19 Antikörper
  • ocp-2 Antikörper
  • OCP-II Antikörper
  • OCP2 Antikörper
  • p19A Antikörper
  • p19Skp1 Antikörper
  • SKP1 Antikörper
  • Skp1a Antikörper
  • S phase kinase-associated protein 1 Antikörper
  • T4O12.17 Antikörper
  • T4O12_17 Antikörper
  • Tceb1l Antikörper
  • UFO INTERACTING PROTEIN 1 Antikörper
  • UIP1 Antikörper
  • zgc:73186 Antikörper

Bezeichner auf Proteinebene für SKP1

S-phase kinase-associated protein 1 , SCF complex component , S-phase kinase-associated protein 1A , S-phase kinase-associated protein 1A (p19A) , OCP-2 , RNA polymerase II elongation factor-like protein OCP2 , SIII , cyclin A/CDK2-associated p19 , cyclin A/CDK2-associated protein p19 , cyclin-A/CDK2-associated protein p19 , organ of Corti protein 2 , organ of Corti protein II , p19skp1 , transcription elongation factor B , p19A

GENE ID SPEZIES
100195936 Salmo salar
100240716 Ovis aries
100340043 Oryctolagus cuniculus
100528639 Ictalurus punctatus
393716 Danio rerio
462063 Pan troglodytes
474682 Canis lupus familiaris
549273 Xenopus (Silurana) tropicalis
735335 Pan troglodytes
6500 Homo sapiens
287280 Rattus norvegicus
615427 Bos taurus
416319 Gallus gallus
100174716 Pongo abelii
380538 Xenopus laevis
843928 Arabidopsis thaliana
21402 Mus musculus
100135616 Cavia porcellus
Ausgewählte Anbieter für anti-SKP1 (SKP1) Antikörper
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