FOXO3 Proteine (FOXO3)

Bezeichnung:
Forkhead Box O3 Proteine (FOXO3)
Auf www.antikoerper-online.de finden Sie aktuell 9 Forkhead Box O3 (FOXO3) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen FOXO3 Antikörper (305) und FOXO3 Kits (42) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 369 FOXO3 Produkte verfügbar.
Synonyme:
1110048B16Rik, 2010203A17Rik, AF6q21, C76856, Fkhr2, Fkhrl1, FKHRL1P2, foxO, FOXO-3, FOXO2, foxO3, FoxO3A, wu:fb50g02, wu:fi33f07, xfoxo3, zgc:92176
alle Proteine anzeigen Gen GeneID UniProt
FOXO3 2309 O43524
FOXO3 56484 Q9WVH4
Ratte FOXO3 FOXO3 294515  

Weitere Synonyme anzeigen

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Am meisten referenzierte FOXO3 Proteine

  1. Human FOXO3 Protein expressed in HEK-293 Cells - ABIN2712289 : Thompson, Larson, Vidrine, Barrios, Navarro, Meyers, Simms, Prajapati, Chitsike, Hellman, Baker, Watkins: FOXO3-NF-κB RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

Weitere Proteine zu FOXO3 Interaktionspartnern

Zebrafish Forkhead Box O3 (FOXO3) Interaktionspartner

  1. by modulating hypoxia-inducible factor activity via up-regulation of VHL (zeige VHL Proteine), FOXO3a (foxo3b) plays an important role in survival in response to hypoxic stress.

  2. This study provided novel evidence of FoxO3a in the embryonic neurodevelopment from zebrafish to other mammals.

Human Forkhead Box O3 (FOXO3) Interaktionspartner

  1. Data suggest that forkhead box O3A protein (FoxO3a) might be a prognostic biomarker or a potential therapeutic target in glioblastoma.

  2. our data demonstrated that FOXO3 is essential for CD44 expression and the properties of cancer stem cells (CSCs). Our data also indicated that patients with high FOXO3 activation signatures had poor prognoses. This evidence suggested that cGMP induction and FOXO3 inhibition could be ideal candidates for pancreatic CSC

  3. adipose stem cell extract regulates Abeta (zeige APP Proteine)-induced mitochondrial apoptosis via regulation of P53 (zeige TP53 Proteine)/foxo3a pathway

  4. Human T2D kidneys exhibited more RPTC apoptosis and lower expression of hnRNP F (zeige HNRNPF Proteine), SIRTUIN-1 (zeige SIRT1 Proteine), and FOXO3alpha than nondiabetic kidneys.

  5. acetylation is permissive for generation of the apoptotic form of FOXO3 and the activity of SIRT1 (zeige SIRT1 Proteine) and particularly SIRT7 (zeige SIRT7 Proteine) regulate this process in vivo, allowing control of monocyte apoptosis in response to LPS (zeige IRF6 Proteine).

  6. ectopic expression of the Foxo3P, Foxo3 circular RNA and Foxo3 mRNA could all suppress tumor growth and cancer cell proliferation and survival.

  7. overall survival and progression-free survival were not found to be affected by FOXO3a expression. Cytoplasmic expression of FOXO3a is frequently found in retinoblastoma and may be involved in pathogenesis

  8. In prostate cancer, FOXO3a, and YB-1 (zeige YBX1 Proteine) play inverse reciprocal roles as a tumor-suppressor gene and oncogene (zeige RAB1A Proteine), respectively, regulated by ERK (zeige EPHB2 Proteine) signaling.

  9. miR (zeige MLXIP Proteine)-34a/sirtuin-1 (zeige SIRT1 Proteine)/foxo3a might play an important role in genistein reversal of ox-LDL-induced oxidative damage in HUVECs.

  10. Results indicate that cordycepin promotes caveolin-1 (CAV1 (zeige CAV1 Proteine))upregulation to enhance c-jun N-terminal kinase (JNK)/forkhead box O3A protein (Foxo3a) signaling pathway activation, inducing apoptosis in lung cancer cells.

Mouse (Murine) Forkhead Box O3 (FOXO3) Interaktionspartner

  1. Data, including data from studies using transgenic/knockout mice, suggest that FoxO3 activation via post-translational phosphorylation can both induce and maintain autophagic activities in renal tubule epithelium in response to injury from unilateral ureteral obstruction; under these conditions, nuclear expression of FoxO3 is up-regulated in hypoxic proximal tubules exhibiting high levels of autophagy.

  2. The Foxo3-Eomes (zeige EOMES Proteine) pathway is central to achieve the complete specialized gene program required for pathogenic Th1 (zeige HAND1 Proteine) cell differentiation.

  3. these results show that Cdk5 (zeige CDK5 Proteine)-mediated phospho-regulation of Foxo3 can activate several genes that promote neuronal death and aberrant Abeta (zeige APP Proteine) processing, thereby contributing to the progression of neurodegenerative pathologies.

  4. the transcription factor Forkhead box O3 (FoxO3) was found to be an essential regulator of the maintenance of pluripotency in dormant embryonic stem cells.

  5. Loss of Foxo3 function resulted in more severe arthritis in vivo (both clinically and histologically) and was associated with higher titers of anticollagen antibodies and interleukin-6 (zeige IL6 Proteine) in the blood.

  6. results indicate that DNA damage accrued as a result of elevated ROS in Foxo3(-/-) mutant HSPC is at least partially reversible

  7. Foxo1 (zeige FOXO1 Proteine), Foxo3a, and Foxo4 (zeige FOXO4 Proteine) in chondrocytes regulate endochondral bone formation.

  8. Data show that resveratrol reduced mitochondrial reactive oxygen species (mROS) generation by promoting Sirt3 (zeige SIRT3 Proteine) enrichment within the mitochondria and subsequent upregulation of FoxO3a-mediated mitochondria gene expression of PGC-1alpha and SOD2 (zeige SOD2 Proteine).

  9. Regulatory loop between FOXO3 and lipid droplets is required for intestinal inflammation.

  10. Maternal diabetes induced caspase 3 (zeige CASP3 Proteine)-dependent apoptosis in Sca1 (zeige ATXN1 Proteine)(+) cardiac progenitor cells derived from embryonic day 17.5 (E17.5). Both maternal diabetes and high glucose in vitro activated the pro-apoptotic transcription factor, Forkhead O 3a (FoxO3a) via dephosphorylation at threonine 32 (Thr (zeige TRH Proteine)-32) residue.

Pig (Porcine) Forkhead Box O3 (FOXO3) Interaktionspartner

  1. These results indicate that myostatin (zeige MSTN Proteine) mediates maternal low protein diet-induced growth retardation, through epigenetic regulation involving FoxO3 and glucocorticoid receptor (zeige NR3C1 Proteine) binding to its promoter.

  2. In granulosa cells, cell death is induced by transfection of FOXO3. FOXO3 mRNA in granulosa cells increases during atresia; FOXO3 protein is abundant in granulosa cells of early atretic follicles. (FOXO3 AA sequence homology with human/mouse FOXO3)

  3. PTEN, FOXO3A and PKB (zeige AKT1 Proteine) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

  4. Primordial oocytes are dormant in prepubertal pigs by a FOXO3-related mechanism to establish a nongrowing oocyte pool in the ovary, and that a transient knockdown of the FOXO3 activates the primordial oocytes to enter the growth phase.

  5. FoxO3a was localized in the granulosa cells of follicles at all stages and was extensively localized in the cytoplasma of the luteinized granulosa cells of corpora lutea

Cow (Bovine) Forkhead Box O3 (FOXO3) Interaktionspartner

  1. NO/protein kinase (zeige CDK7 Proteine) G (PKG (zeige PRKG1 Proteine))-dependent downregulation of PGC-1 alpha and the ROS (zeige ROS1 Proteine) detoxification system in endothelial cells are mediated by the PI3K/Akt (zeige AKT1 Proteine) signaling pathway and subsequent inactivation of transcription factor Foxo3a.

  2. FOXO is a key regulator of ROS (zeige ROS1 Proteine)-induced apoptosis in mammalian cells.

FOXO3 Protein Überblick

Protein Überblick

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with FOXO3

  • forkhead box O3 (FOXO3)
  • forkhead box O3A (foxo3a)
  • forkhead box O3 (foxo3)
  • forkhead box O3 (foxO3)
  • forkhead box O3 (Foxo3)
  • 1110048B16Rik Protein
  • 2010203A17Rik Protein
  • AF6q21 Protein
  • C76856 Protein
  • Fkhr2 Protein
  • Fkhrl1 Protein
  • FKHRL1P2 Protein
  • foxO Protein
  • FOXO-3 Protein
  • FOXO2 Protein
  • foxO3 Protein
  • FoxO3A Protein
  • wu:fb50g02 Protein
  • wu:fi33f07 Protein
  • xfoxo3 Protein
  • zgc:92176 Protein

Bezeichner auf Proteinebene für Forkhead Box O3 Proteine (FOXO3)

forkhead box O3 , forkhead box O3A , fb50g02 , fi33f07 , forkhead box O protein , forkhead box protein O3-like , forkhead box protein O3 , forkhead homolog (rhabdomyosarcoma) like 1 , forkhead in rhabdomyosarcoma-like 1 , forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1 , forkhead box O3a , forkhead protein FKHR2 , xFoxO3 , forkhead box O3A transcription factor

GENE ID SPEZIES
445015 Canis lupus familiaris
494532 Danio rerio
462921 Pan troglodytes
700731 Macaca mulatta
100066558 Equus caballus
100125025 Xenopus (Silurana) tropicalis
100303473 Saccoglossus kowalevskii
100406446 Callithrix jacchus
100451077 Pongo abelii
100600519 Nomascus leucogenys
2309 Homo sapiens
56484 Mus musculus
444992 Xenopus laevis
481954 Canis lupus familiaris
733621 Sus scrofa
294515 Rattus norvegicus
535530 Bos taurus
100713179 Cavia porcellus
421769 Gallus gallus
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