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MTTP Proteine (MTTP)

Bezeichnung:
Microsomal Triglyceride Transfer Protein Proteine (MTTP)
Auf www.antikoerper-online.de finden Sie aktuell 5 Microsomal Triglyceride Transfer Protein (MTTP) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MTTP Antikörper (47) und MTTP Kits (29) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 86 MTTP Produkte verfügbar.
Synonyme:
1810043K16Rik, ABL, CG9342, CT3751, Dmel\\CG9342, dMTP, Dusg, Fpn1, IREG1, MTP, MTP1, MTTP, Ol5, Pcm, Slc11a3, Slc39a1, wu:fd36b01, zgc:111876
alle Proteine anzeigen Gen GeneID UniProt
MTTP 17777 O08601
Ratte MTTP MTTP 310900  
MTTP 4547 P55157

Weitere Synonyme anzeigen

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Weitere Proteine zu MTTP Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Microsomal Triglyceride Transfer Protein (MTTP) Interaktionspartner

  1. promotes assembly and secretion of human apolipoprotein B (zeige APOB Proteine)

  2. the phospholipid transfer activity of MTP is sufficient for the assembly and secretion of primordial apoB (zeige APOB Proteine) lipoproteins

Zebrafish Microsomal Triglyceride Transfer Protein (MTTP) Interaktionspartner

  1. analysis of developmental expression and nutritional regulation of zebrafish homolog to mammalian microsomal triglyceride transfer protein large subunit

  2. In a genetic study of lipid transport and metabolism, larval levels of microsomal triglyceride transfer protein (Mtp), the protein responsible for packaging triacylglycerol and beta-lipoproteins into lipoprotein particles, are unchanged by feeding.

Pig (Porcine) Microsomal Triglyceride Transfer Protein (MTTP) Interaktionspartner

  1. MTTP is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption.

  2. There appears to be an interaction between the porcine MTTP genotype and the type of fat source in the pig diet, which would agree with the previous results on the biology of MTTP biology.

Cow (Bovine) Microsomal Triglyceride Transfer Protein (MTTP) Interaktionspartner

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (zeige APOB Proteine), ApoE (zeige APOE Proteine), MTP, and LDLR (zeige LDLR Proteine), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  2. after calving the apolipoprotein B(100 (zeige APOB Proteine)) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP) and apolipoprotein E (zeige APOE Proteine) messenger RNA abundance were higher in the liver

  3. measurements of the transfer of phospholipids (PLs (zeige CTSC Proteine)) and cholesteryl esters (CEs)to acceptor vesicles by purified MTP showed TAG transfer activity was the most robust, and CE and PL transfer activities were 60-71% and 5-13% of the TAG transfer activity

Mouse (Murine) Microsomal Triglyceride Transfer Protein (MTTP) Interaktionspartner

  1. data provide the first in vivo evidence of the transcriptional regulatory activity of beta-apocarotenoids and identify microsomal triglyceride transfer protein and its transcription factors as the targets of their action. This study demonstrates that beta-carotene induces a feed-forward mechanism in the placenta to enhance the assimilation of beta-carotene for proper embryogenesis.

  2. The results suggest that physiologic hepcidin (zeige HAMP Proteine) levels are insufficient to alter Fpn levels within the retinal pigment epithelium and Muller cells, but may limit iron transport into the retina from vascular endothelial cells.

  3. PHARMACOLOGICAL STUDY OF NEW COMPOUNDS ACTING AS REGULATORS OF 18-KDA TRANSLOCATOR PROTEIN (zeige TSPO Proteine) LIGANDS

  4. In Angiotensin II treated mice, duodenal divalent metal transporter-1 (zeige SLC11A2 Proteine) and ferroportin (zeige SLC40A1 Proteine) expression levels were increased and hepatic hepcidin (zeige HAMP Proteine) mRNA expression and serum hepcidin (zeige HAMP Proteine) concentration were reduced.

  5. Intestine-specific MTP (zeige LAPTM4A Proteine) and global ACAT2 (zeige SOAT2 Proteine) deficiency lowers acute cholesterol absorption with chylomicrons and HDLs (zeige CSF1R Proteine)

  6. Mice infected with Salmonella typhimurium have increased duodenal expression of the iron exporter ferroportin-1 (zeige SLC40A1 Proteine), consistent with increased uptake of dietary iron.

  7. Results suggest that reduction in ferroportin (zeige SLC40A1 Proteine) levels in Alzheimer's disease brains are likely associated with cerebral ischaemia, inflammation, loss of neurons due to protein misfolding, senile plaque formation and possibly ageing process itself

  8. intestine-specific Mttp deletion is beneficial in young septic mice but harmful in aged mice

  9. identified microsomal triglyceride transfer protein, which we show is also under the transcriptional regulation of C/EBPbeta (zeige CEBPB Proteine) and -delta, as a novel player in the presentation of endogenous lipid antigens by adipocytes

  10. effects of reducing either systemic or liver-specific MTP (zeige LAPTM4A Proteine) activity on cholesterol metabolism and reverse cholesterol transport

Human Microsomal Triglyceride Transfer Protein (MTTP) Interaktionspartner

  1. In chronic hepatitis C patients infected with HCV genotype 3 and with the TT/GT genotype of the MTTP -493G/T SNP, a significant increase in hepatic steatosis was observed, which may indicate that this SNP has a significant influence on the accumulation of triglycerides in hepatocytes.

  2. High expression of MTTP is associated with high carotid intima-media thickness.

  3. MTP (zeige MT1B Proteine) Gene Variants are associated with Homozygous Familial Hypercholesterolemia.

  4. the N-terminal domain of MTP (zeige MT1B Proteine) is important for its lipid transfer activity

  5. These studies indicated that SAP18 (zeige SAP18 Proteine) expression enhanced the recruitment of mSin3A in coordination with TRIB1 (zeige TRIB1 Proteine) to MTTP regulatory elements and increased MTTP expression.

  6. Results present evidence that MTTP polymorphisms could modulate the lipid homeostasis to determine the serum lipids and increase risk of non-alcoholic fatty liver disease.

  7. Findings from meta-analysis indicate that the MTP (zeige MT1B Proteine) -493G/T polymorphism may contribute to the development of non-alcoholic fatty liver disease. Thus, the MTP (zeige MT1B Proteine) -493G/T polymorphism may be a biomarker for the early detection of the disease.

  8. Homozygous MTTP mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia.

  9. MTTP SNPs (GG, GT, TT) and alleles (G, T) in the chronic hepatitis C (genotype 4) patients versus the uninfected controls were 70%, 21%, 9% & 80.5%, 19.5% versus 10%, 87.5%, 2.5% & 53.8%, 46.3%, respectively (p=0.0001).

  10. The MTP (zeige MT1B Proteine)-493G/T polymorphism modulates postprandial apoB48 and apoB100 (zeige APOB Proteine) of triglyceride-rich lipoproteins in familial combined hyperlipidemia

MTTP Protein Überblick

Protein Überblick

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Alternative names and synonyms associated with MTTP

  • Microsomal triacylglycerol transfer protein (Mtp)
  • microsomal triglyceride transfer protein (mtp)
  • microsomal triglyceride transfer protein (MTTP)
  • microsomal triglyceride transfer protein (Mttp)
  • mitochondrially encoded tRNA proline (MT-TP)
  • solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1)
  • 1810043K16Rik Protein
  • ABL Protein
  • CG9342 Protein
  • CT3751 Protein
  • Dmel\\CG9342 Protein
  • dMTP Protein
  • Dusg Protein
  • Fpn1 Protein
  • IREG1 Protein
  • MTP Protein
  • MTP1 Protein
  • MTTP Protein
  • Ol5 Protein
  • Pcm Protein
  • Slc11a3 Protein
  • Slc39a1 Protein
  • wu:fd36b01 Protein
  • zgc:111876 Protein

Bezeichner auf Proteinebene für MTTP

microsomal triacylglycerol transfer protein , CG9342-PA , Mtp-PA , microsomal triglyceride transfer protein , microsomal triglyceride transfer protein large subunit , stalactite , stl , microsomal triglyceride transfer protein (large polypeptide, 88kDa) , microsomal triglyceride transfer protein B , microsomal triglyceride transfer protein, large subunit , SLC11A3 iron transporter , duodenal-specific , ferroportin 1 , ferroportin-1 , iron-regulated transporter 1 , metal transporter protein 1 , metal transporting protein 1 , polycythaemia , solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3 , solute carrier family 39 (iron-regulated transporter), member 1 , solute carrier family 40 member 1

GENE ID SPEZIES
35362 Drosophila melanogaster
406207 Danio rerio
471397 Pan troglodytes
422709 Gallus gallus
487873 Canis lupus familiaris
397381 Sus scrofa
280868 Bos taurus
17777 Mus musculus
310900 Rattus norvegicus
4547 Homo sapiens
100734244 Cavia porcellus
100341961 Oryctolagus cuniculus
101110939 Ovis aries
101836921 Mesocricetus auratus
4571 Homo sapiens
53945 Mus musculus
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