TANK-Binding Kinase 1 (TBK1) ELISA Kits

Bezeichnung:
TANK-Binding Kinase 1 ELISA Kits (TBK1)
Auf www.antikoerper-online.de finden Sie aktuell 15 TANK-Binding Kinase 1 (TBK1) ELISA Kits von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TANK-Binding Kinase 1 Antikörper (156) und TANK-Binding Kinase 1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 192 TANK-Binding Kinase 1 Produkte verfügbar.
Synonyme:
1200008B05Rik, AI462036, AW048562, NAK, T2K, TBK1, wu:fk70c05, zgc:136548

TANK-Binding Kinase 1 (TBK1) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für TANK-Binding Kinase 1 Interaktionspartner

Zebrafish TANK-Binding Kinase 1 (TBK1) Interaktionspartner

  1. Fish IRF6 (zeige IRF6 ELISA Kits) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 (zeige MYD88 ELISA Kits) and TBK1, suggesting that differences in the IRF6 (zeige IRF6 ELISA Kits) regulation pattern exist between lower and higher vertebrates.

Human TANK-Binding Kinase 1 (TBK1) Interaktionspartner

  1. Mutations in the TANK-binding kinase 1 (TBK1) gene were identified as a cause for amyotrophic lateral sclerosis (ALS (zeige IGFALS ELISA Kits)) with or without comorbid frontotemporal dementia.

  2. The occurrence of TBK1 mutations in FTD (zeige FTL ELISA Kits) and ALS (zeige IGFALS ELISA Kits) underlines the fact that FTD (zeige FTL ELISA Kits) and ALS (zeige IGFALS ELISA Kits) are part of the same disease spectrum. For future therapeutic trials, characterization of TBK1 mutation carriers in presymptomatic cohorts, such as the genetic frontotemporal dementia initiative (GENFI), is of great importance.

  3. demonstrate a key role of TBK1/IKKepsilon (zeige IKBKE ELISA Kits) in the survival and proliferation of HTLV-1-transformed T cells

  4. Data suggest that Encephalomyocarditis virus 3C protease cleaves TANK and disrupts the TANK-TBK1-IKKepsilon (zeige IKBKE ELISA Kits)-IRF3 (zeige IRF3 ELISA Kits) complex, resulting in reduction in IRF3 (zeige IRF3 ELISA Kits) phosphorylation and type I interferon (zeige IFNA ELISA Kits) production. (TANK = TRAF family member associated NFKB activator (zeige TANK ELISA Kits); TBK1 = TANK binding kinase 1; IKKepsilon (zeige IKBKE ELISA Kits) = inhibitor of nuclear factor kappa B kinase subunit epsilon (zeige IKBKE ELISA Kits); IRF3 (zeige IRF3 ELISA Kits) = interferon regulatory factor 3 (zeige IRF3 ELISA Kits))

  5. Data suggest that changes in inhibitor of nuclear factor kappa B kinase subunit epsilon (IKKepsilon (zeige IKBKE ELISA Kits)) and TANK-binding kinase 1 (TBK1) expression may be involved in the development of intestinal-type gastric cancer.

  6. Here the authors show that recruitment of WIPI2 (zeige WIPI2 ELISA Kits), itself essential for anti-bacterial autophagy, is dependent on the localization of catalytically active TBK1 to the vicinity of cytosolic bacteria.

  7. review of the role of TBK1 in the seemingly unrelated, yet allelic diseases amyotrophic lateral sclerosis (ALS (zeige IGFALS ELISA Kits)), frontotemporal dementia (FTD (zeige FTL ELISA Kits)), normal tension glaucoma (NTG (zeige OPA1 ELISA Kits)) and childhood herpes simplex encephalitis and discuss the role of TBK1 in neuroinflammatory diseases

  8. Enrichment of qualifying variants toward glaucoma was present in all genes except WDR36, in which controls harbored more variants, and TBK1, in which no qualifying variants were detected in cases or controls.

  9. Human herpesvirus 1 ICP27 interacted with TBK1 and STING in a manner that was dependent on TBK1 activity and the RGG motif in ICP27 and inhibited type I IFN induction through the cGAS-STING-TBK1 pathway in human macrophages.

  10. Upon cytosolic DNA stimulation, STAT3 (zeige STAT3 ELISA Kits) Ser (zeige SIGLEC1 ELISA Kits)(754) is directly phosphorylated by TBK1 in a STING-dependent manner. Moreover, Ser (zeige SIGLEC1 ELISA Kits)(754) phosphorylation inhibits cytosolic DNA-induced STAT3 (zeige STAT3 ELISA Kits) transcriptional activity and selectively reduces STAT3 (zeige STAT3 ELISA Kits) target genes that are up-regulated in response to cytosolic DNA

Mouse (Murine) TANK-Binding Kinase 1 (TBK1) Interaktionspartner

  1. USP38 inhibits type I interferon signaling by editing TBK1 ubiquitination through NLRP4 signalosome.

  2. The authors report that Raf kinase inhibitory protein (RKIP (zeige PEBP1 ELISA Kits)) is essential for TBK1 activation and type I interferon (zeige IFNA ELISA Kits) production triggered by viral infection.

  3. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 (zeige FOSL1 ELISA Kits) "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (zeige TRAF3 ELISA Kits)), TIR domain-containing adapter inducing IFN-beta (zeige IFNB1 ELISA Kits) (TRIF (zeige RNF138 ELISA Kits)), and Tank-binding kinase 1 (TBK1) via impairing K63-linked polyubiquitination of TRAF3 (zeige TRAF3 ELISA Kits) and TRIF (zeige RNF138 ELISA Kits).

  4. TBK1 complexes required for the phosphorylation of IRF3 (zeige IRF3 ELISA Kits) and the production of interferon-beta (zeige IFNB1 ELISA Kits) have been identified.

  5. this study reveals a previously unknown ICOS (zeige ICOS ELISA Kits)-TBK1 signaling pathway that specifies the commitment of germinal center follicular helper T cells

  6. Innate immune responses to adenovirus vectors are largely TBK1-dependent in the spleen but TBK1-independent in the liver

  7. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1 (zeige RPS6KB1 ELISA Kits))-STING membrane protein-TANK-binding kinase 1 (TBK1) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (zeige IRF3 ELISA Kits)).

  8. This study suggest that TBK1 exerts pronociceptive effects in inflammatory nociception which are due to both modulation of NF-kappaB dependent genes and regulation of MAPKs and c-fos.

  9. TRIM27 (zeige RFP ELISA Kits) inhibits VSV infection-induced type I IFN production by promoting TBK1 degradation.

  10. Suggest that by reducing production of cAMP in adipocytes, PDE3B, IKKepsilon (zeige IKBKE ELISA Kits) and TBK1 may contribute to the repression of energy expenditure during obesity.

TANK-Binding Kinase 1 (TBK1) Antigen-Profil

Beschreibung des Gens

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Alternative names and synonyms associated with TANK-Binding Kinase 1 (TBK1)

  • TANK-binding kinase 1 (tbk1) Elisa Kit
  • TANK-binding kinase 1 (TBK1) Elisa Kit
  • TANK-binding kinase 1 (LOC100358771) Elisa Kit
  • TANK-binding kinase 1 (Tbk1) Elisa Kit
  • 1200008B05Rik Elisa Kit
  • AI462036 Elisa Kit
  • AW048562 Elisa Kit
  • NAK Elisa Kit
  • T2K Elisa Kit
  • TBK1 Elisa Kit
  • wu:fk70c05 Elisa Kit
  • zgc:136548 Elisa Kit

Bezeichner auf Proteinebene für TANK-Binding Kinase 1 (TBK1) ELISA Kits

serine/threonine-protein kinase TBK1 , TANK-binding kinase 1 , NF-kappa-B-activating kinase , TANK binding kinase 1 , serine/threonine protein kinase TBK1 , serine/threonine-protein kinase TBK1-like , NF-kB-activating kinase , T2K

GENE ID SPEZIES
446351 Xenopus laevis
452047 Pan troglodytes
692289 Danio rerio
717427 Macaca mulatta
100051650 Equus caballus
100125828 Sus scrofa
100216212 Xenopus (Silurana) tropicalis
100358771 Oryctolagus cuniculus
100399701 Callithrix jacchus
100433568 Pongo abelii
100484104 Ailuropoda melanoleuca
100553575 Anolis carolinensis
100582856 Nomascus leucogenys
29110 Homo sapiens
481145 Canis lupus familiaris
533141 Bos taurus
56480 Mus musculus
299827 Rattus norvegicus
417825 Gallus gallus
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