Crk Proteine (CRK)

Auf finden Sie aktuell 10 V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Crk Antikörper (144) und Crk Kits (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 186 Crk Produkte verfügbar.
c-Crk, CG1587, crk, Crk-I, Crk-II, Crk-III, crk2, Crk3, crkII, CrkIII, Crko, D-Crk, dCrk, Dmel\\CG1587, fb34h10, fc05a01, fi19g05, p38, P38C-CRK, v-crk, wu:fb34h10, wu:fc05a01, wu:fc54a04, wu:fi19g05, zgc:100936
alle Proteine anzeigen Gen GeneID UniProt
CRK 1398 P46108
Ratte CRK CRK 54245 Q63768
CRK 12928 Q64010

Crk Proteine (CRK) nach Spezies

Weitere Proteine zu Crk Interaktionspartnern

Zebrafish V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) Interaktionspartner

  1. The adaptor proteins Crk and Crk-like (Crkl (zeige CRKL Proteine)), with which Dock proteins are known to interact physically, are also required for myoblast fusion.

Human V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) Interaktionspartner

  1. Study investigated structures and thermodynamics of the interactions mediated by N-terminal Src homology 3 domain of CrkII and proline-rich motifs (PRMs) of cAbl kinase, highlight the role of interfacial water molecules and the conformational entropy in the SH3:PRM interactions

  2. CrkII mediates IGF-1 (zeige IGF1 Proteine) signaling and further balances pancreatic ductal adenocarcinoma biological behaviors via Erk1/2 and Akt (zeige AKT1 Proteine) pathway

  3. In individuals with class I 17p13.3 microduplications including CRK, we recommend biochemical evaluation of the growth hormone (zeige GH1 PLURAL_@44953@) axis. Providers caring for these patients should be aware of their possible risk for the development of central precocious puberty.

  4. Crk Tyr251 phosphorylation regulate invasive cell phenotypes in glioblastoma.

  5. CsA (zeige ERCC8 Proteine) and FK506 might interfere with selected effector T cell functions via a CrkII-, but not CrkI-dependent mechanisms.

  6. Studied the role of PAK1/Crk axis in transduction of the oncogenic KRAS signal in non-small cell lung cancer (NSCLC).

  7. in human c-CrkII, movement at position 239 and strain at position 272 are not tolerated because the beta-branched residues Ile239 and Val272 restrain the backbone mobility and thus destabilize the cis (zeige CISH Proteine) Pro238 form.

  8. Data indicate the role of tyrosine phosphorylation in regulating modular domain utilization in v-crk sarcoma virus CT10 oncogene homolog (avian) protein (Crk).

  9. evidence uncovered essential roles of CRK in invasive bladder cancer through the hepatocyte growth factor (zeige HGF Proteine)/c-Met/CRK feedback loop for epithelial-mesenchymal transition induction

  10. In this review, we describe the structure and function of the different Crk proteins.

Mouse (Murine) V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) Interaktionspartner

  1. the data suggest that CCRK (zeige CDK20 Proteine) positively regulates the kinetics by which ciliary proteins such as Smoothened and Gli2 are imported into the cilium, and that the efficiency of ciliary recruitment allows for potent responses to Hedgehog (zeige SHH Proteine) signaling over long time periods.

  2. results suggest that Crk and CrkL (zeige CRKL Proteine) play essential overlapping roles in fibroblast growth.

  3. both Crk and CrkL are required for the acquisition of cellular transformation by v-fos, whereas Crk plays a more prominent role than CrkL in v-ras-induced transformation.

  4. results support a model in which Dok1 (zeige DOK1 Proteine) phosphorylation normally suppresses localized Ras pathway activity in Crk-transformed cells via recruitment and/or activation of RasGAP (zeige RASA1 Proteine)

  5. Differential migration of CRK/CRKL (zeige CRKL Proteine)-deficient T cells resulted in efficient graft-versus-leukemia responses with minimal graft-versus-host disease in mice.

  6. Crk1 (zeige MAPK14 Proteine)/2 and CrkL (zeige CRKL Proteine) are physically linked, functionally complement each other during podocyte foot process spreading, and together are required for developing typical foot process architecture.

  7. Data suggest that interactions between Crk (proto-oncogene (zeige RAB1A Proteine) proteins c-crk) and Sos1 (Son of Sevenless homolog 1 (zeige SOS1 Proteine)) involve electrostatic interactions at binding sites.

  8. Results suggest that Crk and CrkL (zeige CRKL Proteine) have critical roles in cell structure and motility by maintaining cytoskeletal integrity.

  9. The v-Crk-myosin-1c interaction, which modulates membrane dynamics by regulating Rac1 activity, is crucial for cell adhesion and spreading.

  10. The authors cloned SH2 domain-containing proteins they named GRBs (for growth factor receptor (zeige RYK Proteine)-bound). They identified GRB-3 as having 77% identity at the protein level and 80% similarity at the DNA level to v-crk.

Crk (CRK) Protein Überblick

Protein Überblick

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Alternative names and synonyms associated with Crk (CRK)

  • CG1587 gene product from transcript CG1587-RD (Crk)
  • v-crk sarcoma virus CT10 oncogene homolog (avian) (crk)
  • v-crk sarcoma virus CT10 oncogene homolog (avian) (CRK)
  • v-crk avian sarcoma virus CT10 oncogene homolog (CRK)
  • v-crk avian sarcoma virus CT10 oncogene homolog (Crk)
  • v-crk avian sarcoma virus CT10 oncogene homolog (crk)
  • v-crk sarcoma virus CT10 oncogene homolog (CRK)
  • v-crk sarcoma virus CT10 oncogene homolog (avian) (Crk)
  • c-Crk Protein
  • CG1587 Protein
  • crk Protein
  • Crk-I Protein
  • Crk-II Protein
  • Crk-III Protein
  • crk2 Protein
  • Crk3 Protein
  • crkII Protein
  • CrkIII Protein
  • Crko Protein
  • D-Crk Protein
  • dCrk Protein
  • Dmel\\CG1587 Protein
  • fb34h10 Protein
  • fc05a01 Protein
  • fi19g05 Protein
  • p38 Protein
  • P38C-CRK Protein
  • v-crk Protein
  • wu:fb34h10 Protein
  • wu:fc05a01 Protein
  • wu:fc54a04 Protein
  • wu:fi19g05 Protein
  • zgc:100936 Protein

Bezeichner auf Proteinebene für CRK

CG1587-PA , CG1587-PB , CG1587-PC , CG1587-PD , CG1587-PE , CG1587-PF , Crk-PA , Crk-PB , Crk-PC , Crk-PD , Crk-PE , Crk-PF , adapter molecule crk , v-crk sarcoma virus CT10 oncogene homolog (avian) , proto-oncogene c-Crk , avian sarcoma virus CT10 (v-crk) oncogene homolog , p38 , proto-oncogene C-crk , v-crk sarcoma virus CT10 oncogene homolog , SH2/SH3 adaptor Crk2 , SH2/SH3 adaptor crk , CT-10 related kinase 3 , proto-oncogene c-crk , v-crk sarcoma virus CT10 oncogene-like protein

43775 Drosophila melanogaster
445234 Danio rerio
512841 Bos taurus
747142 Pan troglodytes
1398 Homo sapiens
54245 Rattus norvegicus
398951 Xenopus laevis
417553 Gallus gallus
12928 Mus musculus
100684309 Canis lupus familiaris
100192444 Sus scrofa
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