anti-CD247 (CD247) Antikörper

Bezeichnung:
anti-CD247 Molecule Antikörper (CD247)
Auf www.antikoerper-online.de finden Sie aktuell 299 CD247 Molecule (CD247) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CD247 Proteine (13) und CD247 Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 329 CD247 Produkte verfügbar.
Synonyme:
4930549J05Rik, A430104F18Rik, AW552088, Cd3, Cd3-eta, CD3-ZETA, CD3H, CD3Q, Cd3z, Cd3zeta, CD247, im:7156386, LOC100136514, LOC100136549, LOC100305023, T3Z, Tcrk, TCRZ, TCRzeta

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Am meisten referenzierte anti-CD247 Antikörper

  1. Human Polyclonal CD247 Primary Antibody für IHC (fro), IHC (p) - ABIN115429 : Henry, Bennett, Piggott, Levett, May, Westley: Expression of the pNR-2/pS2 protein in diverse human epithelial tumours. in British journal of cancer 1991 (PubMed)
    Zeige alle 5 Referenzen für 115429

  2. Mouse (Murine) Monoclonal CD247 Primary Antibody für FACS - ABIN4898315 : Lin, Xu, Jin, Zhong, Di, Lin: CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice. in Fertility and sterility 2009 (PubMed)
    Zeige alle 2 Referenzen für 4898315

  3. Mouse (Murine) Monoclonal CD247 Primary Antibody für FACS - ABIN4898307 : Lemay, Rintoul, Kus, Paterson, Garcia, Falls, Ferreira, Bridle, Conrad, Tang, Diallo, Arulanandam, Le Boeuf, Garson, Vanderhyden, Stojdl, Lichty, Atkins, Parato, Bell, Auer: Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine. in Molecular therapy : the journal of the American Society of Gene Therapy 2012 (PubMed)

  4. Human Monoclonal CD247 Primary Antibody für IP, WB - ABIN967304 : Hussey, Clayton, Diener, McConkey, Howard, Rodewald, DAdamio, Dallenbach, Stein, Schmidt: Overexpression of CD3 eta during thymic development does not alter the negative selection process. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)

  5. Human Monoclonal CD247 Primary Antibody für ICS - ABIN1177046 : Alberola-Ila, Takaki, Kerner, Perlmutter: Differential signaling by lymphocyte antigen receptors. in Annual review of immunology 1997 (PubMed)

  6. Human Monoclonal CD247 Primary Antibody für FACS - ABIN118360 : van Oers, Teh, Irving, Tiong, Weiss, Teh: Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. in Journal of immunological methods 1994 (PubMed)

Weitere Antikörper gegen CD247 Interaktionspartner

Zebrafish CD247 Molecule (CD247) Interaktionspartner

  1. The structure of the adaptor protein cd3zeta has been identified in the zebrafish genome.

Mouse (Murine) CD247 Molecule (CD247) Interaktionspartner

  1. ITAM sequence diversity is required for optimal TCR signal transduction and subsequent T cell maturation

  2. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 (zeige CCR7 Antikörper) and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

  3. There is an early (within seconds) interaction between CD3zeta and the coreceptor CD8 that is independent of the binding of CD8 to MHC.

  4. The resting TCR localized in the disordered domain of giant plasma membrane (PM) vesicles (GPMVs) and PM spheres (PMSs) and single and nanoclustered TCRs are found in the high-density fractions in sucrose gradients.

  5. When Ly108 (zeige SLAMF6 Antikörper) is engaged in trans during cell-cell interactions, Ly108 (zeige SLAMF6 Antikörper)-CD3zeta interactions are promoted in a manner that uniquely depends on Ly108 (zeige SLAMF6 Antikörper) TM domain, leading to more efficient CD3zeta dephosphorylation.

  6. Two transcription factor binding sites and a long non-coding RNA are identified within the Cd247 gene.

  7. Zfat (zeige ZFAT Antikörper)-deficiency results in a loss of CD3zeta phosphorylation with dysregulation of ERK (zeige EPHB2 Antikörper) and Egr (zeige EGR1 Antikörper) activities leading to impaired positive selection.

  8. The results of this study supported the model that the procognitive function of CD3zeta may be mediated through its involvement in the NMDAR (zeige GRIN1 Antikörper) downstream signaling pathway leading to CaMKII (zeige CAMK2G Antikörper)-dependent LTP (zeige SCP2 Antikörper) induction.

  9. T cell CD3zeta deficiency enables multiorgan tissue inflammation.

  10. Tyrosine phosphorylation of the TCR-zeta cytoplasmic domain regulates its association with the plasma membrane

Human CD247 Molecule (CD247) Interaktionspartner

  1. CD3 (zeige CD3 Antikörper)/28-activated T cells expanded in IL-7 (zeige IL7 Antikörper) and IL-15 (zeige IL15 Antikörper) produced greater expansion of memory stem T cells and central memory T cell-derived T cells compared with IL-2 (zeige IL2 Antikörper). Our strategy provides a powerful tool to elucidate the characteristics of CAR-modified T cells, regardless of the protocol used for expansion, reveals the functional properties of each expanded T cell subset.

  2. Multiple mutations were found in CD247 complementary DNAs (cDNAs) cloned from the patient as well as in cDNA and genomic DNA from other individuals, suggesting that genetic variation in this gene is frequent.

  3. Single-nucleotide polymorphism in CD247 gene is associated with sclerotic graft-versus-host disease.

  4. CD3Z hypermethylation was significantly correlated with SLE. CD3Z hypermethylation is an SLE risk factor that can be modified by environmental factors and is associated with more severe SLE clinical manifestations, which are related to deranged T cell function by downregulating the CD3zeta-chain.

  5. Linkage and association studies revealed a chromosomal region in which a novel type 1 diabetes (T1D)/autoimmune thyroid disease (AITD) susceptibility gene, CD247, is located and showed association between T1D/AITD and several variants in this gene. These results suggests that common susceptibility genes act in concert with variants of CD247 to generate genetic risk for T1D/AITD in this population.

  6. Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta chain down-regulation via caspase-3 (zeige CASP3 Antikörper) activation in oral cancer.

  7. SRSF1 (zeige SRSF1 Antikörper) regulates CD3zeta expression in human T cells and may contribute to the T cell defect in systemic lupus erythematosus.

  8. In localized colorectal cancer carriers, mRNA-based CD3Z/CD8 (zeige CD8A Antikörper) profiling of tumor immune response may have stage, site and tissue-specific prognostic significance, along with ESR1 (zeige ESR1 Antikörper) expression.

  9. Our study independently confirms and extends the association of SLE with CD247, which is shared by various autoimmune disorders and supports a common T-cell-mediated mechanism.

  10. we observed decreased CD3 (zeige CD3 Antikörper) surface expression, reduced ZAP-70 (zeige ZAP70 Antikörper) abundance and increased histone H3 (zeige HIST3H3 Antikörper)-acetylation in activated T lymphocytes after 5 minutes of clinorotation and a transient downregulation of CD3 (zeige CD3 Antikörper) and stable downregulation of IL-2R

Pig (Porcine) CD247 Molecule (CD247) Interaktionspartner

CD247 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with CD247

  • CD247 antigen like (cd247l) Antikörper
  • CD3zeta-2 (LOC100136514) Antikörper
  • CD3zeta-1 (LOC100136549) Antikörper
  • CD3 zeta (LOC100305023) Antikörper
  • CD247 molecule (CD247) Antikörper
  • CD247 antigen (cd247) Antikörper
  • CD247 antigen (Cd247) Antikörper
  • Cd247 molecule (Cd247) Antikörper
  • 4930549J05Rik Antikörper
  • A430104F18Rik Antikörper
  • AW552088 Antikörper
  • Cd3 Antikörper
  • Cd3-eta Antikörper
  • CD3-ZETA Antikörper
  • CD3H Antikörper
  • CD3Q Antikörper
  • Cd3z Antikörper
  • Cd3zeta Antikörper
  • CD247 Antikörper
  • im:7156386 Antikörper
  • LOC100136514 Antikörper
  • LOC100136549 Antikörper
  • LOC100305023 Antikörper
  • T3Z Antikörper
  • Tcrk Antikörper
  • TCRZ Antikörper
  • TCRzeta Antikörper

Bezeichner auf Proteinebene für anti-CD247 Molecule (CD247) Antikörper

CD247 antigen like , cd3zetal , CD3zeta-like , CD247 antigen-like , CD3zeta-2 , T-cell surface glycoprotein CD3 zeta chain , CD3zeta-1 , CD3 zeta , CD247 molecule , cd3zeta , CD3 antigen, zeta polypeptide , CD3-zeta/eta , T-cell receptor T3 eta chain , CD247 antigen, zeta subunit , CD3Z antigen, zeta polypeptide (TiT3 complex) , CD3zeta chain , T-cell antigen receptor complex, zeta subunit of CD3 , T-cell receptor T3 zeta chain , TCR zeta chain , CD247 antigen , T-cell receptor CD3 subunit zeta , T-cell receptor CD3, subunit zeta , CD3 zeta chain , CD3 Zeta chain

GENE ID SPEZIES
100101465 Danio rerio
100136514 Salmo salar
100136549 Salmo salar
100305023 Ictalurus punctatus
748272 Pan troglodytes
100101654 Danio rerio
12503 Mus musculus
919 Homo sapiens
25300 Rattus norvegicus
397302 Sus scrofa
100008617 Oryctolagus cuniculus
443436 Ovis aries
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