anti-DVL1 (DVL1) Antikörper

anti-Dishevelled Segment Polarity Protein 1 Antikörper (DVL1)
Auf finden Sie aktuell 6 Dishevelled Segment Polarity Protein 1 (DVL1) Antikörper von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DVL1 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 14 DVL1 Produkte verfügbar.
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DVL1 1855 O14640

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Human Dishevelled Segment Polarity Protein 1 (DVL1) Interaktionspartner

  1. Authors conclude that the planar cell polarity (PCP (zeige PRCP Antikörper)) pathway contributes significantly to the motility and hence the invasiveness of glioblastoma multiforme (GBM) cells, and that Nrdp1 (zeige RNF41 Antikörper) acts as a negative regulator of PCP (zeige PRCP Antikörper) signaling by inhibiting Dvl (zeige DVL2 Antikörper) through a novel polyubiquitination mechanism.

  2. The DEP (zeige ZDHHC21 Antikörper) domain of Dishevelled (zeige DVL2 Antikörper) undergoes a conformational switch, from monomeric to swapped dimer, to trigger DIX domain-dependent polymerization and signaling to beta-catenin (zeige CTNNB1 Antikörper).

  3. two mutually exclusive functions of the DEP (zeige ZDHHC21 Antikörper) domain in Wnt (zeige WNT2 Antikörper) signal transduction - binding to Frizzled to recruit Dishevelled (zeige DVL2 Antikörper) to the receptor complex, is reported.

  4. we show that Wnt5a (zeige WNT5A Antikörper) rapidly represses rDNA gene transcription in breast cancer cells and generates a chromatin state with reduced transcription of rDNA by RNA polymerase I (zeige POLR1C Antikörper) (Pol I). These effects were specifically dependent on Dishevelled1 (DVL1), which accumulates in nucleolar organizer regions (NORs) and binds to rDNA regions of the chromosome.

  5. Data show that dishevelled (zeige DVL2 Antikörper) proteins DVL1, 2 and 3 were exclusively expressed in chronic lymphatic leukaemia (CLL) cells as compared to normal peripheral blood mononuclear cells (PBMCs).

  6. The secreted frizzled-related protein (zeige SFRP2 Antikörper) and disheveled protein family members appear to be actively involved in the pathogenesis of primary testicular germ cell tumors.

  7. Data show that receptor for activated C kinase 1 (RACK1 (zeige GNB2L1 Antikörper)) interacts with Dishevelled (Dvl (zeige DVL2 Antikörper)) proteins and promotes their lysosomal degradation, and this effect is enhanced by autophagy induction.

  8. TMEM88 stimulated triple negative breast cancer cell invasion by interacting with DVLl.

  9. Specific -1 frameshift variants in the penultimate exon of DVL1 cause autosomal-dominant Robinow syndrome.

  10. Results show that coexpression of IQGAP1 (zeige IQGAP1 Antikörper) and Dvl (zeige DVL2 Antikörper) in the cytoplasm and nucleus was correlated with the lymph nodal metastase and poor prognosis of non-small cell lung cancer.

DVL1 Antigen-Profil

Beschreibung des Gens

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Alternative names and synonyms associated with DVL1

  • dishevelled segment polarity protein 1 (DVL1) Antikörper
  • DVL Antikörper
  • DVL1L1 Antikörper
  • DVL1P1 Antikörper

Bezeichner auf Proteinebene für DVL1

DSH homolog 1 , dishevelled 1 (homologous to Drosophila dsh) , dishevelled, dsh homolog 1 , dishevelled-1 , segment polarity protein dishevelled homolog DVL-1

1855 Homo sapiens
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