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anti-Human CYP3A4 Antikörper:
anti-Rat (Rattus) CYP3A4 Antikörper:
anti-Mouse (Murine) CYP3A4 Antikörper:
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Human Polyclonal CYP3A4 Primary Antibody für IHC (p), WB - ABIN514838
Yamashita, Honda, Nio, Nakamoto, Yamashita, Takamura, Tani, Zen, Kaneko: Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation. in Cancer research 2010
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Human Polyclonal CYP3A4 Primary Antibody für Func, WB - ABIN2473177
Chirkov YuYu, Tyshchuk, Severina: Guanylate cyclase in human platelets with different aggregability. in Experientia 1990
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Human Monoclonal CYP3A4 Primary Antibody für ICC, FACS - ABIN969512
van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. in Drug metabolism and disposition: the biological fate of chemicals 2009
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Human Polyclonal CYP3A4 Primary Antibody für ELISA - ABIN4302113
Choi, Skipper, Wishnok, Tannenbaum: Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450. in Drug metabolism and disposition: the biological fate of chemicals 2005
Human Polyclonal CYP3A4 Primary Antibody für IP, WB - ABIN947776
Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. in Pharmacology research & perspectives 2014
Human Polyclonal CYP3A4 Primary Antibody für WB - ABIN514839
De Bock, Colin, Boussery, Van Bocxlaer: Development and validation of an enzyme-linked immunosorbent assay for the quantification of cytochrome 3A4 in human liver microsomes. in Talanta 2012
Cow (Bovine) Polyclonal CYP3A4 Primary Antibody für WB - ABIN2784528
Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. in Clinical pharmacology and therapeutics 2014
It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (zeige POR Antikörper) and cytochrome b(5 (zeige CYB5A Antikörper)).
The DEGs (zeige DEGS1 Antikörper), such as AGTR1 (zeige AGTR1 Antikörper), CYP3A4 and CYP4A11 (zeige CYP4A11 Antikörper) may play critical roles in the development of HTN likely via the regulation by hsa (zeige CD24 Antikörper)-miR (zeige MLXIP Antikörper)-26b-5p and taking part in some pathways.
The results demonstrated the important role of the CYP (zeige PPIG Antikörper) 3A4*1B allelic variant as risk factor for developing resistance to antiepileptic drugs in pediatric patients with epilepsy
The established method provides a sensitive tool to evaluate the CYP3A4 protein in human liver homogenates from patients with normal or chronic/severe hepatic injury.
None of the patients with Regorafenib-induced severe toxic hepatitis had CYP3A4 gene mutations. Similar polymorphisms in UGT1A9 (zeige UGT1A9 Antikörper) gene promoter region were found in both patients who presented acute hepatitis.
We sought to determine the relation between 17-alpha hydroxyprogesterone caproate plasma concentrations, progesterone receptor (zeige PGR Antikörper) single nucleotide polymorphisms and single nucleotide polymorphisms in CYP3A4 and CYP3A5 (zeige CYP3A5 Antikörper) and spontaneous preterm birth.
homozygous AA carriers of the CYP3A4 gene respond better to treatment with transdermal buprenorphine for critical limb ischemia
Data suggest that metabolism (and possibly pharmacokinetics) of hypnotic nitrazepam involves liver enzymes AOX1 (aldehyde oxidase 1 (zeige AOX1 Antikörper)), NAT2 (N-acetyltransferase 2 (zeige NAT2 Antikörper)), AADAC (arylacetamide deacetylase (zeige AADAC Antikörper)), and CYP3A4 (cytochrome P450 3A4).
Cross-talk between pregnane X receptor (zeige NR1I2 Antikörper) and AhR (zeige AHR Antikörper) plays a role in rifampicin regulation of CYP3A4 gene expression.
We observed an association between ABCB1 (zeige ABCB1 Antikörper) 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (zeige PPIG Antikörper) 3A4 *1B, 3A5*3 and ABCB1 (zeige ABCB1 Antikörper) C1236T.
The authors found a correlation between genetic SNP variations in CYP3A4 enzyme and tacrolimus blood levels in this Jordanian kidney transplant recipients.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
cytochrome P450 3A4
, cytochrome P450, family 3, subfamily A, polypeptide 4
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4
, Cytochrome P450 CM3A-10
, cytochrome P450 3A21
, 1,8-cineole 2-exo-monooxygenase
, P450-III, steroid inducible
, albendazole monooxygenase
, albendazole sulfoxidase
, cytochrome P450 3A3
, cytochrome P450 HLp
, cytochrome P450 NF-25
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3
, cytochrome P450-PCN1
, glucocorticoid-inducible P450
, nifedipine oxidase
, quinine 3-monooxygenase
, taurochenodeoxycholate 6-alpha-hydroxylase
, cytochrome P450 CYP3A12
, cytochrome P450 3A80