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RAB5 Proteine (RAB5A)

Bezeichnung:
RAB5A, Member RAS Oncogene Family Proteine (RAB5A)
Auf www.antikoerper-online.de finden Sie aktuell 21 RAB5A, Member RAS Oncogene Family (RAB5A) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAB5 Antikörper (202) und RAB5 Kits (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 244 RAB5 Produkte verfügbar.
Synonyme:
2410015H04Rik, AI663973, AU021172, DDBDRAFT_0168594, DDBDRAFT_0229401, DDB_0168594, DDB_0229401, nnyRab5a, RAB5, RAB5A
alle Proteine anzeigen Gen GeneID UniProt
RAB5A 5868 P20339
RAB5A 271457 Q9CQD1
Ratte RAB5A RAB5A 64633  

Weitere Synonyme anzeigen

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Am meisten referenzierte RAB5 Proteine

  1. Human RAB5 Protein expressed in Escherichia coli (E. coli) - ABIN1686703 : Woodman: Biogenesis of the sorting endosome: the role of Rab5. in Traffic (Copenhagen, Denmark) 2001 (PubMed)
    Zeige alle 4 Referenzen für ABIN1686703

  2. Human RAB5 Protein expressed in Escherichia coli (E. coli) - ABIN666700 : Yao-Borengasser, Varma, Bodles, Rasouli, Phanavanh, Lee, Starks, Kern, Spencer, Rashidi, McGehee, Fried, Kern: Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. in The Journal of clinical endocrinology and metabolism 2007 (PubMed)
    Zeige alle 2 Referenzen für ABIN666700

Weitere Proteine zu RAB5 Interaktionspartnern

Human RAB5A, Member RAS Oncogene Family (RAB5A) Interaktionspartner

  1. downregulated Rab5a led to slowed cell growth, decreased numbers of migrated cells, decreased numbers of cells at the G0G1 phase and a higher apoptosis rate. However, PDGF (zeige PDGFA Proteine) significantly rescued these phenomena caused by siRNA against Rab5a

  2. results suggest a new mechanism in which Rab5 induces a change in flexibility of EEA1 (zeige EEA1 Proteine), generating an entropic collapse force that pulls the captured vesicle towards the target membrane to initiate docking and membrane fusion

  3. structural differences may provide an opportunity to selectively target one Rab5 state and lead to new approaches in the development of Rab5-specific therapies

  4. Data show that rab5 GTP-Binding Protein (Rab5a) is overexpressed in human hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) and contributes to cancer cell proliferation and invasion through regulation of FAK (zeige PTK2 Proteine) and AKT (zeige AKT1 Proteine) signaling.

  5. TTBK2 (zeige TTBK2 Proteine) down-regulates GluK2 (zeige GRIK2 Proteine) activity by decreasing the receptor protein abundance in the cell membrane via RAB5-dependent endocytosis.

  6. Results indicate that persistent rab5 overactivation through beta-cleaved carboxy-terminal fragment of APP (zeige APP Proteine)-APPL1 (zeige APPL1 Proteine) interactions constitutes a novel APP (zeige APP Proteine)-dependent pathogenic pathway in Alzheimer's disease

  7. Results demonstrate that DRG2 (zeige DRG2 Proteine) is an endosomal protein and a key regulator of Rab5 deactivation and Tfn (zeige Tf Proteine) recycling.

  8. Rab5a is involved in critical events not only at the beginning of the autophagy process with endosomal formation (initiation), but also later on, being important for autophagosome sealing and fusion with lysosomes through an interplay with Beclin 1 (zeige BECN1 Proteine).

  9. Findings indicate the role of CMTM7 (zeige CMTM7 Proteine) protein in the regulation of epidermal growth factor receptor (EGFR (zeige EGFR Proteine))-AKT (zeige AKT1 Proteine) proto-oncogene (zeige RAB1A Proteine) protein signaling in tumor cells, and as a molecule related to Rab5 GTP-binding protein activation.

  10. Low expression of RAB5A is associated with metastasis in prostate cancer.

Mouse (Murine) RAB5A, Member RAS Oncogene Family (RAB5A) Interaktionspartner

  1. These data highlight a requirement of Rab5 and the endosomal system for the regulation of gluconeogenic gene expression that has important implications for metabolic diseases.

  2. Inpp5e (zeige INPP5E Proteine), through functional interactions with Rab20 (zeige RAB20 Proteine) on the phagosome, activates Rab5, which, in turn, increases PtdIns3P and delays phagosome acidification.

  3. FGF21 (zeige FGF21 Proteine) has a role in promoting endothelial cell angiogenesis through a dynamin-2 (zeige DNM2 Proteine) and Rab5 dependent pathway

  4. In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin (zeige NCDN Proteine) palmitoylation in its targeting to Rab5-positive endosomes.

  5. In mammalian cells, p110beta acts as a molecular sensor for growth factor availability and induces autophagy by activating a Rab5-mediated signaling cascade.

  6. Data show that Rinl is closely associated with the cytoskeleton and thus contributes to the spatial control of Rab5a and Rab22 signaling at actin-positive compartments.

  7. Data reveal the affinity of Rabex-5 (zeige RABGEF1 Proteine)/Rabaptin-5/Rab5-GTP (zeige AK3 Proteine) interaction in the cell, which is quantitatively related to the Rabex-5 (zeige RABGEF1 Proteine) concentration for the onset of the indirect

  8. Rab5 regulates and coordinates different endocytic mechanisms through its effector Rabankyrin-5 (zeige ANKFY1 Proteine)

  9. Using retroviral expression and siRNA Rab5a silencing, data demonstrate that Rab5a is essential for the large endosome phenotype and for localization of mannose receptor.

  10. the recruitment of Gapex-5 (zeige GAPVD1 Proteine) to phagosomes through the microtubule network induces transient Rab5 activation

Pig (Porcine) RAB5A, Member RAS Oncogene Family (RAB5A) Interaktionspartner

  1. Expression of dominant negative Rab5 and Rab7 (zeige RAB7A Proteine) mutants, but not the dominant negative Rab11 (zeige RAB11A Proteine) mutant, significantly inhibited classical swine fever virus replication. These results were confirmed by silencing of Rab5 and Rab7 (zeige RAB7A Proteine).

  2. Dominant-negative mutant rab5 inhibits FMDV infection of IBRS-2 cells.

RAB5 (RAB5A) Protein Überblick

Protein Überblick

Required for the fusion of plasma membranes and early endosomes (By similarity).

Alternative names and synonyms associated with RAB5 (RAB5A)

  • rab5A protein (rab5A)
  • Rab5a, GTPase (Rab5a)
  • hypothetical protein (Rab5a)
  • Rab GTPase (rab5A)
  • Ras-related protein Rab-5A (rab5a)
  • ras-related protein rab-5a (rab5a)
  • RAB5A, member RAS oncogene family (rab5a)
  • RAB5A, member RAS oncogene family (RAB5A)
  • RAB5A, member RAS oncogene family (LOC100350923)
  • RAB5A, member RAS oncogene family (Rab5a)
  • 2410015H04Rik Protein
  • AI663973 Protein
  • AU021172 Protein
  • DDBDRAFT_0168594 Protein
  • DDBDRAFT_0229401 Protein
  • DDB_0168594 Protein
  • DDB_0229401 Protein
  • nnyRab5a Protein
  • RAB5 Protein
  • RAB5A Protein

Bezeichner auf Proteinebene für RAB5A

rab5A protein , Rab5a, GTPase , hypothetical protein , Ras-related protein Rab-5A , ras-related protein rab-5a , RAB5A, member RAS oncogene family , ras-related protein Rab-5A , RAS-associated protein RAB5A , small GTP-binding protein rab5 , GTP-binding protein (rab5)

GENE ID SPEZIES
553894 Lotus japonicus
812700 Plasmodium falciparum 3D7
7197170 Phaeodactylum tricornutum CCAP 1055/1
8618246 Dictyostelium discoideum AX4
100195116 Salmo salar
100528297 Ictalurus punctatus
380227 Xenopus laevis
460217 Pan troglodytes
697712 Macaca mulatta
699014 Macaca mulatta
100350923 Oryctolagus cuniculus
5868 Homo sapiens
271457 Mus musculus
64633 Rattus norvegicus
404008 Canis lupus familiaris
539764 Bos taurus
100144499 Sus scrofa
420649 Gallus gallus
101099995 Felis catus
100302084 Ovis aries
100723790 Cavia porcellus
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