anti-IQGAP1 (IQGAP1) Antikörper

Bezeichnung:
anti-IQ Motif Containing GTPase Activating Protein 1 Antikörper (IQGAP1)
Auf www.antikoerper-online.de finden Sie aktuell 104 IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IQGAP1 Kits (10) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 122 IQGAP1 Produkte verfügbar.
Synonyme:
AA682088, D7Ertd237e, D7Ertd257e, HUMORFA01, mKIAA0051, p195, SAR1
Alle Antikörper anzeigen Gen GeneID UniProt
IQGAP1 8826 P46940
IQGAP1 361598  
IQGAP1 29875 Q9JKF1

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-IQGAP1 (IQGAP1) Antikörper

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anti-Human IQGAP1 Antikörper:

anti-Rat (Rattus) IQGAP1 Antikörper:

anti-Mouse (Murine) IQGAP1 Antikörper:

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Am meisten referenzierte anti-IQGAP1 Antikörper

  1. Dog (Canine) Monoclonal IQGAP1 Primary Antibody für IF, IP - ABIN968063 : Hart, Callow, Souza, Polakis: IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs. in The EMBO journal 1996 (PubMed)
    Zeige alle 5 Referenzen für 968063

  2. Human Monoclonal IQGAP1 Primary Antibody für IF, WB - ABIN395438 : Liang, Fu, Zhang, Tang, Zhou, Wei, Chen: Honokiol inhibits HepG2 migration via down-regulation of IQGAP1 expression discovered by a quantitative pharmaceutical proteomic analysis. in Proteomics 2010 (PubMed)
    Zeige alle 5 Referenzen für 395438

  3. Human Polyclonal IQGAP1 Primary Antibody für ELISA, WB - ABIN4327480 : Ren, Li, Sacks: IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling. in The Journal of biological chemistry 2008 (PubMed)

  4. Mouse (Murine) Polyclonal IQGAP1 Primary Antibody für ELISA, WB - ABIN314835 : Bi, Mancias, Goldberg: Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31. in Developmental cell 2007 (PubMed)

  5. Human Polyclonal IQGAP1 Primary Antibody für ICC, IF - ABIN438475 : Sun, Kapuria, Peterson, Fang, Bornmann, Bartholomeusz, Talpaz, Donato: Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. in Blood 2011 (PubMed)

  6. Human Polyclonal IQGAP1 Primary Antibody für IF (cc), IF (p) - ABIN737796 : Fang, Zhang, Liu, Li, Zhou, Song, Zhao, Feng, Zhang, Li, Wen: PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation. in Stem cells and development 2014 (PubMed)

Weitere Antikörper gegen IQGAP1 Interaktionspartner

Human IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) Interaktionspartner

  1. findings suggest a novel role of IQGAP1 in insulin (zeige INS Antikörper)-regulated interaction between caveolae and cytoskeletal elements of the adipocyte, and that this is quelled in the diabetic state

  2. Alterated IQGAP1/Rho GTPase (zeige RACGAP1 Antikörper) signaling in myeloproliferative neoplasm erythrocytes is dependent on JAK2 (zeige JAK2 Antikörper)/CALR (zeige CALR Antikörper) mutational status.

  3. our data suggest that IQ-domain GTPase-activating protein (zeige RASA1 Antikörper) 1 may promote the malignant phenotype of invasive ductal carcinoma via canonical Wnt (zeige WNT2 Antikörper) signaling, and it could be used as a potential prognostic biomarker for breast cancer patients.

  4. IQ domain of IQGAP1 is both necessary and sufficient for binding to ERK1 (zeige MAPK3 Antikörper) and ERK2 (zeige MAPK1 Antikörper), as well as to the MAPK (zeige MAPK1 Antikörper) kinases MEK1 (zeige MAP2K1 Antikörper) and MEK2 (zeige MAP2K2 Antikörper).

  5. Data indicate that the IQGAP1 N-terminal fragment spanning residues 1-191 (CHDF) binds to both F-actin and Ca(2 (zeige CA2 Antikörper)+)/calmodulin (zeige CALM1 Antikörper).

  6. These data were confirmed by phosphomimetic mutation of serine 1443 to glutamate within RGCT, which led to a significant reduction of IQGAP1 affinity for CDC42 and RAC1, clearly disclosing the critical role of RGCT for these interactions.

  7. These data reveal that IQGAP1 binds to YAP (zeige YAP1 Antikörper) and modulates its co-transcriptional function, suggesting that IQGAP1 participates in Hippo signaling.

  8. The results indicated that IQGAP1 was expressed at higher levels in glioma tissues compared with in normal brain tissues. IQGAP1siRNA significantly inhibited cell proliferation, and cell adhesion, migration and invasion.

  9. IQGAP1 protein is involved in normal cell physiology as well as oncologic processes.

  10. after AKT-mediated phosphorylation at serine 319, FOXO1 binds to IQGAP1, a hub for activation of the MAPK pathway, and impedes IQGAP1-dependent phosphorylation of ERK1/2 (pERK1/2).

Mouse (Murine) IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) Interaktionspartner

  1. Data highlight a unique mechanism of formin (zeige FMN1 Antikörper) action in which mDia1 and INF2 (zeige INF2 Antikörper) function in series to stabilize MTs (zeige NEU2 Antikörper) and point to IQGAP1 as a scaffold that facilitates the activation of one formin (zeige FMN1 Antikörper) by another.

  2. Hectd1 (zeige HECTD1 Antikörper) regulates the protein level of IQGAP1 through ubiquitination.

  3. Loss of IQGAP1 results in impaired insulin (zeige INS Antikörper) signaling and glucose homeostasis in vivo.

  4. These data reveal that IQGAP1 binds to YAP (zeige YAP1 Antikörper) and modulates its co-transcriptional function, suggesting that IQGAP1 participates in Hippo signaling.

  5. IQGAP1 has a strong signaling relationship with Ras genes in induction of cancer and it is considered as a key gene for induction or suppression of the hepatocellular carcinoma.

  6. IQGAP1 has the potential to modulate airway contraction severity in acute asthma.

  7. we propose that IQGAP1 acts as a small GTPase (zeige RACGAP1 Antikörper) scaffolding platform within the small GTPase (zeige RACGAP1 Antikörper) network, and recruits and/or regulates small GTPases, small GTPase (zeige RACGAP1 Antikörper) regulators and effectors to orchestrate cell behavior

  8. This finding has new implications for involvement of IQGAP1 in cell polarization and migration events and potentially in cell cycle-associated nuclear envelope assembly/disassembly.

  9. IQGAP1 contributes to AngII-induced apoptosis of podocytes by interacting with the ERK1/2 (zeige MAPK1/3 Antikörper) signaling protein

  10. RSPO (zeige RSPO1 Antikörper)-LGR4 (zeige LGR4 Antikörper) not only induces the clearance of RNF43 (zeige RNF43 Antikörper)/ZNRF3 (zeige ZNRF3 Antikörper) to increase Wnt receptor levels but also recruits IQGAP1 into the Wnt (zeige WNT2 Antikörper) signaling complex.

IQGAP1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Alternative names and synonyms associated with IQGAP1

  • IQ motif containing GTPase activating protein 1 (IQGAP1) Antikörper
  • IQ motif containing GTPase activating protein 1 (Iqgap1) Antikörper
  • AA682088 Antikörper
  • D7Ertd237e Antikörper
  • D7Ertd257e Antikörper
  • HUMORFA01 Antikörper
  • mKIAA0051 Antikörper
  • p195 Antikörper
  • SAR1 Antikörper

Bezeichner auf Proteinebene für IQGAP1

RasGAP-like with IQ motifs , ras GTPase-activating-like protein IQGAP1 , Cdc42-Rac1 effector protein

GENE ID SPEZIES
8826 Homo sapiens
361598 Rattus norvegicus
29875 Mus musculus
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