anti-TEK (TEK) Antikörper

anti-TEK Tyrosine Kinase, Endothelial Antikörper (TEK)
Auf finden Sie aktuell 400 TEK Tyrosine Kinase, Endothelial (TEK) Antikörper von 30 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TEK Kits (69) und TEK Proteine (40) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 529 TEK Produkte verfügbar.
AA517024, CD202B, DKFZp469E064, Hyk, TEK, Tie-2, tie2, VMCM, VMCM1
Alle Antikörper anzeigen Gen GeneID UniProt
TEK 21687  
TEK 7010 Q02763
TEK 89804  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TEK (TEK) Antikörper

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anti-Mouse (Murine) TEK Antikörper:

anti-Human TEK Antikörper:

anti-Rat (Rattus) TEK Antikörper:

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Am meisten referenzierte anti-TEK Antikörper

  1. Human Monoclonal TEK Primary Antibody für FACS - ABIN4896647 : Schauer, Starlinger, Reiter, Jahn, Zajc, Buchberger, Bachleitner-Hofmann, Bergmann, Stift, Gruenberger, Brostjan: Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer. in PLoS ONE 2012 (PubMed)
    Zeige alle 8 Referenzen für 4896647

  2. Human Polyclonal TEK Primary Antibody für EIA - ABIN358489 : Cascone, Audero, Giraudo, Napione, Maniero, Philips, Collard, Serini, Bussolino: Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1. in Blood 2003 (PubMed)
    Zeige alle 5 Referenzen für 358489

  3. Human Monoclonal TEK Primary Antibody für IHC (fro), WB - ABIN967565 : Dumont, Gradwohl, Fong, Puri, Gertsenstein, Auerbach, Breitman: Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. in Genes & development 1994 (PubMed)
    Zeige alle 4 Referenzen für 967565

  4. Human Monoclonal TEK Primary Antibody für EIA, FACS - ABIN155165 : Harris, Reusch, Barleon, Hang, Dobbs, Marme: Soluble Tie2 and Flt1 extracellular domains in serum of patients with renal cancer and response to antiangiogenic therapy. in Clinical cancer research : an official journal of the American Association for Cancer Research 2001 (PubMed)
    Zeige alle 4 Referenzen für 155165

  5. Human Monoclonal TEK Primary Antibody für EIA, FACS - ABIN155164 : Chin, Greenman, Reusch, Gardiner, Marme, Monson: Changes in serum soluble VEGFR-1 and Tie-2 receptors in colorectal cancer patients following surgical resections. in Anticancer research 2004 (PubMed)
    Zeige alle 3 Referenzen für 155164

  6. Human Polyclonal TEK Primary Antibody für IHC, ELISA - ABIN1532488 : Ziegler, Bird, Schneringer, Schooley, Baum: Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta. in Oncogene 1993 (PubMed)
    Zeige alle 2 Referenzen für 1532488

  7. Human Polyclonal TEK Primary Antibody für IF, ELISA - ABIN1531402 : Sjöblom, Jones, Wood, Parsons, Lin, Barber, Mandelker, Leary, Ptak, Silliman, Szabo, Buckhaults, Farrell, Meeh, Markowitz, Willis, Dawson, Willson, Gazdar, Hartigan, Wu, Liu, Parmigiani, Park et al.: The consensus coding sequences of human breast and colorectal cancers. ... in Science (New York, N.Y.) 2006 (PubMed)
    Zeige alle 2 Referenzen für 1531402

  8. Mouse (Murine) Monoclonal TEK Primary Antibody für ICC, FACS - ABIN259889 : Fernandez-Ruiz, Kawa, Berasain, Iñiguez, Schmitz, Martinez-Ansó, Iñarrairaegui, Herrero, Sangro, DAvola, Quiroga, Qian, Prieto: Treatment of murine fulminant hepatitis with genetically engineered endothelial progenitor cells. in Journal of hepatology 2011 (PubMed)

  9. Human Monoclonal TEK Primary Antibody für IHC (p), IHC - ABIN258840 : Rodrigues-Pinto, Berry, Piper-Hanley, Hanley, Richardson, Hoyland: Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2016 (PubMed)

Weitere Antikörper gegen TEK Interaktionspartner

Mouse (Murine) TEK Tyrosine Kinase, Endothelial (TEK) Interaktionspartner

  1. Hydroxysafflor yellow A promotes angiogenesis in ischemic hindlimb via the angiopoi (zeige ANGPT1 Antikörper)etin 1/ Tie-2 signaling pathway.

  2. TBMS1 further stimulated the proteasomal degradation of vascular endothelial growth factor receptor-2 (VEGFR2 (zeige KDR Antikörper)) and Tie2 in endothelial cells, which down-regulated AKT (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling.

  3. results implicate common genetic variation at the TIE2 locus as a determinant of vascular leak-related clinical outcomes from common infections, suggesting new tools to identify individuals at unusual risk for deleterious complications of infection

  4. the results suggest that an increased level of TNF-alpha (zeige TNF Antikörper) together with concomitant upregulation of Tie2/Angiopoietin signaling have critical roles in severe dengue infection.

  5. Data support an interactive model of Tie1 (zeige TIE1 Antikörper) and Tie2 function, in which dynamically regulated Tie1 (zeige TIE1 Antikörper) versus Tie2 expression determines the net positive or negative effect of Tie1 (zeige TIE1 Antikörper) on Tie2 signaling.

  6. These results suggest that Tie2 signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (zeige VCAM1 Antikörper).

  7. Report accelerated lung regeneration by platelet-rich plasma extract through Lrp5 (zeige LRP5 Antikörper)/Tie2 pathway.

  8. Rapamycin improves TIE2-mutated venous malformation

  9. an EPC (zeige TCF21 Antikörper) SDF-1 (zeige CXCL12 Antikörper)/CXCR4 (zeige CXCR4 Antikörper) axis plays an important role in bone fracture healing using Tie2-Cre(ER) CXCR4 (zeige CXCR4 Antikörper) conditional knockout mice.

  10. Immunohistological analysis of the tumors showed that Tie2-dependent a6 gene deletion was associated with reduced tumor vascularization and with reduced infiltration of proangiogenic Tie2-expressing macrophages

Human TEK Tyrosine Kinase, Endothelial (TEK) Interaktionspartner

  1. ANG-1 (zeige ANGPT1 Antikörper), ANG-2 (zeige ANGPT2 Antikörper) and TIE-2 levels were significantly increased in placenta of non-complicated ART pregnancies compared to placentas from spontaneous conception.

  2. Our data suggest that interaction of TEK and CYP1B1 (zeige CYP1B1 Antikörper) contributes to primary congenital glaucoma pathogenesis and argue that TEK-CYP1B1 (zeige CYP1B1 Antikörper) may perform overlapping as well as distinct functions in manifesting the disease etiology.

  3. High Tie-2 expression is associated with Primary Myelofibrosis.

  4. In this study, we found that angiopoietins and Tie receptors were highly expressed in cervical cancer cells. Tie-2 expression in tumor cells predicted poorer prognosis.Our data support that dual inhibition of Ang-1 (zeige ANGPT1 Antikörper) and Ang-2 (zeige ANGPT2 Antikörper) may be an alternative target for anti-angiogenic adjuvant therapy in advanced or recurrent cervical squamous cell cancer.

  5. Data show that fibulin-5 (zeige FBLN5 Antikörper) strongly binds to the endothelial cell surface reducing endothelial cell viability and interfering with the signaling pathways of the Ang-1 (zeige ANGPT1 Antikörper)/TIE-2 receptor axis.

  6. Blue rubber bleb nevus syndrome cased by somatic mutation of TEK.

  7. Ang (zeige ANG Antikörper),Tie1 (zeige TIE1 Antikörper) and Tie2 play roles in vascular development and pathogenesis of vascular diseases.[review]

  8. In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (zeige ANGPT2 Antikörper) Ang-1 (zeige ANGPT1 Antikörper), but not the receptor binding domain of Ang-2 (zeige ANGPT2 Antikörper), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (zeige MAPK1 Antikörper) signaling in the presence of both Ang-1 (zeige ANGPT1 Antikörper) and fibronectin (zeige FN1 Antikörper)

  9. Activation of Tie2 by subcutaneous injections of AKB-9778 combined with suppression of vascular endothelial growth factor (VEGF) causes a significantly greater reduction in Diabetic macular edema than that seen with suppression of VEGF alone.

  10. We could therefore conclude that angiogenesis is an important event in the development of common skin warts, and the upregulation of both Ang1 (zeige ANGPT1 Antikörper) and -2 and their binding receptor Tie2 may play a role in the angiogenesis associated with the development of these lesions.

Cow (Bovine) TEK Tyrosine Kinase, Endothelial (TEK) Interaktionspartner

  1. Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells.

Zebrafish TEK Tyrosine Kinase, Endothelial (TEK) Interaktionspartner

  1. observations demonstrate that Tie2 is an important regulator of tip cell behaviors

  2. Tie-1 (zeige TIE1 Antikörper) and Tie-2 are not required for early heart development, yet they have redundant roles for the maintenance of endocardial-myocardial connection in later stages.

TEK Antigen-Profil

Beschreibung des Gens

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations\; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Alternative names and synonyms associated with TEK

  • TEK tyrosine kinase, endothelial (TEK) Antikörper
  • TEK tyrosine kinase, endothelial (LOC100356675) Antikörper
  • TEK tyrosine kinase, endothelial (tek) Antikörper
  • endothelial-specific receptor tyrosine kinase (Tek) Antikörper
  • TEK tyrosine kinase, endothelial (Tek) Antikörper
  • AA517024 Antikörper
  • CD202B Antikörper
  • DKFZp469E064 Antikörper
  • Hyk Antikörper
  • TEK Antikörper
  • Tie-2 Antikörper
  • tie2 Antikörper
  • VMCM Antikörper
  • VMCM1 Antikörper

Bezeichner auf Proteinebene für TEK

growth factor receptor Tie2/Tek , TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal) , Angiopoietin-1 receptor , TEK tyrosine kinase, endothelial , angiopoietin-1 receptor-like , STK1 , angiopoietin-1 receptor , endothelial tyrosine kinase , mTIE2 , p140 TEK , tunica interna endothelial cell kinase , tyrosine kinase with Ig and EGF homology domains-2 , tyrosine-protein kinase receptor TEK , tyrosine-protein kinase receptor TIE-2 , hTIE2 , soluble TIE2 variant 1 , soluble TIE2 variant 2 , protein-tyrosine kinase Tie2 , endothelial-specific receptor tyrosine kinase , tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2 , endothelium-specific receptor tyrosine kinase 2 , tyrosine-protein kinase receptor Tie-2

403714 Canis lupus familiaris
465028 Pan troglodytes
707455 Macaca mulatta
100174302 Pongo abelii
100356675 Oryctolagus cuniculus
100408334 Callithrix jacchus
100492432 Xenopus (Silurana) tropicalis
100606897 Nomascus leucogenys
21687 Mus musculus
7010 Homo sapiens
396729 Sus scrofa
89804 Rattus norvegicus
280939 Bos taurus
30747 Danio rerio
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