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PDGFD Proteine (PDGFD)

Bezeichnung:
Platelet Derived Growth Factor D Proteine (PDGFD)
Auf www.antikoerper-online.de finden Sie aktuell 12 Platelet Derived Growth Factor D (PDGFD) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PDGFD Antikörper (66) und PDGFD Kits (47) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 132 PDGFD Produkte verfügbar.
Synonyme:
1110003I09Rik, IEGF, PDGFD, rSCDGF-B, SCDGF-B, Scdgfb
alle Proteine anzeigen Gen GeneID UniProt
PDGFD 80310 Q9GZP0
PDGFD 66018 Q9EQT1
PDGFD 71785 Q925I7

Weitere Synonyme anzeigen

PDGFD Proteine (PDGFD) nach Spezies

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Am meisten referenzierte PDGFD Proteine

  1. Human PDGFD Protein expressed in Escherichia coli (E. coli) - ABIN1098679 : Bergsten, Uutela, Li, Pietras, Ostman, Heldin, Alitalo, Eriksson: PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. in Nature cell biology 2001 (PubMed)
    Zeige alle 2 Referenzen für ABIN1098679

Weitere Proteine zu PDGFD Interaktionspartnern

Human Platelet Derived Growth Factor D (PDGFD) Interaktionspartner

  1. This study suggested that epithelial-mesenchymal transition process can be triggered by the PDGF-D/PDGFRb (zeige PDGFRB Proteine) axis in tongue squamous cell carcinoma, and then involved in the tumor cell invasion via activation of p38 (zeige CRK Proteine)/AKT (zeige AKT1 Proteine)/ERK (zeige EPHB2 Proteine)/ epithelial-mesenchymal transition pathway.

  2. No specific genotype of rs974819 of Platelet-derived growth factor D demonstrated increased cardiovascular mortality in the total population, however, the male group with genotypes A/A and G/A demonstrated an increased risk that persisted in a multivariate evaluation where adjustments were made for well-known cardiovascular risk factors.

  3. There are four platelet-derived growth factor (PDGF (zeige PDGFA Proteine)) genes (PDGFA (zeige PDGFA Proteine), PDGFB (zeige PDGFB Proteine), PDGFC (zeige PDGFC Proteine) and PDGFD) that reside on chromosomes 7, 22, 4 and 11.

  4. polymorphism of rs7950273 in the PDGFD gene is not associated with ischaemic stroke in the Chinese Han population

  5. Novel findings reveal a new paradigm in matriptase (zeige ST14 Proteine) activation involving PDGF-D-specific signal transduction leading to extracellular acidosis.

  6. PDGF-D expression is associated with miR (zeige MLXIP Proteine)-106a and Twist1 (zeige TWIST1 Proteine) in HCC (zeige FAM126A Proteine) patients

  7. PDGF-D is highly expressed by ASCs, where it acts as a potent mitogenic factor.

  8. PDGFD, CDH1 and SLIT2 are upregulated in low grade meningiomas and schwannomas compared with healthy tissue.

  9. PDGF (zeige PDGFA Proteine)-DD secreted by gastric cancer derived mesenchymal stem cells is capable of promoting gastric cancer cell progression in vitro and in vivo.

  10. Data suggest that targeting platelet-derived growth factor-D as a strategy for endometrial cancer treatment.

Mouse (Murine) Platelet Derived Growth Factor D (PDGFD) Interaktionspartner

  1. Inactivation of the Pdgfd gene resulted in a mild phenotype in C57BL/6 mice, and the offspring was viable, fertile and generally in good health.

  2. PDGF-D intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1 (zeige TIMP1 Proteine)/MMP-2 (zeige MMP2 Proteine)/MMP (zeige MMP2 Proteine)-9 (zeige MMP9 Proteine) system, and PDGF-D signaling is mediated through both PDGF (zeige PDGFA Proteine)-alpha and -beta receptors.

  3. Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex

  4. PDGF D represents a potentially promising target for prostate carcinoma treatment resistance in the absence of PTEN function, and warrants further laboratory evaluation and clinical study.

  5. Data indicate that the proteolytic processing of full-length PDGF-D is required for PDGF-D activation of preosteoclasts, and that beta-PDGFR (zeige PDGFRB Proteine) is present in activated osteoclasts.

  6. identified PDGF (zeige PDGFA Proteine)-DD as an important target gene for antiangiogenic therapy due to its pleiotropic effects on vascular and non-vascular cells. PDGF (zeige PDGFA Proteine)-DD inhibition may offer new therapeutic options to treat neovascular diseases

  7. Failure of laminin alpha4-mediated down-regulation of PDGF (zeige PDGFA Proteine) activity contributes to the progressive renal lesions in this animal model.

  8. These results suggest that PDGF-D induce cellular transformation and promote tumour growth by accelerating the proliferation rate of the tumour cells, and by stimulation of tumour neovascularization.

  9. PDGF-D plays an important role in the pathogenesis of tubulointerstitial injury through binding of PDGF (zeige PDGFA Proteine)-Rbeta in obstructive ureteral nephropathy

  10. PDGF (zeige PDGFA Proteine)-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns.

PDGFD Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.

Alternative names and synonyms associated with PDGFD

  • platelet derived growth factor D (PDGFD)
  • platelet derived growth factor D (Pdgfd)
  • platelet-derived growth factor, D polypeptide (Pdgfd)
  • 1110003I09Rik Protein
  • IEGF Protein
  • PDGFD Protein
  • rSCDGF-B Protein
  • SCDGF-B Protein
  • Scdgfb Protein

Bezeichner auf Proteinebene für PDGFD

platelet derived growth factor D , PDGF-D , platelet-derived growth factor D , platelet-derived growth factor D-like , iris-expressed growth factor , spinal cord derived growth factor B , spinal cord-derived growth factor B , spinal cord-derived growth factor-B , SCDGF-B , platelet-derived growth factor, D polypeptide , spinal-cord derived growth factor-B protein

GENE ID SPEZIES
466765 Pan troglodytes
100061488 Equus caballus
100172718 Pongo abelii
100398033 Callithrix jacchus
100586178 Nomascus leucogenys
80310 Homo sapiens
66018 Rattus norvegicus
100008912 Oryctolagus cuniculus
100713757 Cavia porcellus
479460 Canis lupus familiaris
525931 Bos taurus
418978 Gallus gallus
101117784 Ovis aries
71785 Mus musculus
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