You are viewing an incomplete version of our website. Please click to reload the website as full version.

IGF1R Proteine (IGF1R)

Bezeichnung:
Insulin-Like Growth Factor 1 Receptor Proteine (IGF1R)
Auf www.antikoerper-online.de finden Sie aktuell 39 Insulin-Like Growth Factor 1 Receptor (IGF1R) Proteine von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IGF1R Antikörper (469) und IGF1R Kits (47) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 571 IGF1R Produkte verfügbar.
Synonyme:
A330103N21Rik, CD221, D930020L01, DKFZp469I0618, hyft, IGF-1R, IGF1R, IGFIR, IGFIRC, IGFR, IGFR1, JTK13, xIGF-1R, xigf1r, xIGFR
alle Proteine anzeigen Gen GeneID UniProt
IGF1R 3480 P08069
IGF1R 25718 P24062
IGF1R 16001 Q60751

Weitere Synonyme anzeigen

IGF1R Proteine (IGF1R) nach Spezies

Wählen Sie die gewünschte Spezies

Am meisten referenzierte IGF1R Proteine

  1. Human IGF1R Protein expressed in Human Cells - ABIN2002215 : Tollefsen, Stoszek, Thompson: Interaction of the alpha beta dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation. in Biochemistry 1991 (PubMed)
    Zeige alle 5 Referenzen für ABIN2002215

Weitere Proteine zu IGF1R Interaktionspartnern

Horse (Equine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. This study evaluated the expression of IGF-1 (zeige IGF1 Proteine) receptor, insulin receptor (zeige INSR Proteine) AND IGF-1 (zeige IGF1 Proteine) in the lammelar tissue of horses with insulin (zeige INS Proteine)-induced hyperinsulinemia.

  2. The laminar cell types expressing insulin receptor (zeige INSR Proteine) and/or insulin-like growth factor-1 receptor and the effect of dietary carbohydrates on their expression are reported.

  3. Somatomedin (IGF-I (zeige IGF1 Proteine)) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor is present in spermatogonia, spermatocytes and Leydig cells.[IGF-I receptor]

Human Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. Quantification of IGF-1 (zeige IGF1 Proteine) Receptor May Be Useful in Diagnosing Polycythemia Vera (zeige IGF2BP3 Proteine)

  2. In adenocarcinoma, insulin receptor (zeige INSR Proteine)-B and IGF-1R expression was 5- to 6-fold higher than normal endometrium.

  3. the existence of a dynamic negative feedback loop in the regulation of IGF1R and miR (zeige MLXIP Proteine)-493 mediated via Snail (zeige SNAI1 Proteine), is reported.

  4. Although smaller than WT (wild type) mice, old-aged Igf1r(+/-) had increased adiposity and exhibit increased lipogenesis. We hypothesize that IGF-1 (zeige IGF1 Proteine) resistance initially causes a transient increase in insulin (zeige INS Proteine) signaling thereby promoting a lipogenic phenotype, which subsequently leads to insulin (zeige INS Proteine) resistance.

  5. HASF (C3orf58) is a novel ligand of IGF1R.

  6. The age-associated higher expression of miR (zeige MLXIP Proteine)-96 and miR (zeige MLXIP Proteine)-145 might contribute to the lower expression of IGF-1R while the higher expression of miR (zeige MLXIP Proteine)-96, miR (zeige MLXIP Proteine)-145 and miR (zeige MLXIP Proteine)-9 might contribute to the lower expression of FOXO1 (zeige FOXO1 Proteine) in peripheral blood mononuclear cells of aging humans.

  7. Previously characterized disease-causing mutations in IGF2, IGF1R, IGF2R (zeige IGF2R Proteine), or IGFALS (zeige IGFALS Proteine) all were found in the general population but with allele frequencies of <1:30,000.

  8. These results indicate that mutagenesis and skin carcinogenesis in IGF-1 (zeige IGF1 Proteine)-deficient geriatric skin may be caused by defects in multiple cellular responses to UVB-induced DNA damage, including through a failure to properly suppress DNA synthesis on UVB-damaged DNA templates.

  9. Authors identified Insulin (zeige INS Proteine) Growth Factor (IGF)1 (zeige IGF1 Proteine) receptor as the signal positively regulated by TGFbeta (zeige TGFB1 Proteine) implicated in ovarian tumor cell proliferation.

  10. IGF-1R downregulation may have a regulatory impact after initiation of hepatic lineage commitment.

Pig (Porcine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. IGF-I (zeige IGF1 Proteine), IGF-II, and IGFBP-3 (zeige IGFBP3 Proteine) mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.

  2. IL-1beta (zeige IL1B Proteine) impaired the actions of IGF-I (zeige IGF1 Proteine) at a point distal to the IGF receptor

  3. IGF-1R is expressed in porcine somatostatin (zeige SST Proteine)-containing islet D-cells

  4. This study suggests an association between the affinity of insulin (zeige INS Proteine) receptors and number of IGF-1 (zeige IGF1 Proteine) receptors with placental and/or fetal growth.

  5. mRNA expression of IGF-I receptor

Cow (Bovine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. A total of 1169 cows of 4 pure breeds (Polish Holstein Friesian, Montbeliarde, Jersey and Holstein Friesian) were genotyped. The T (IGF1R/e2/MspI) and G (IGF1R/e2/TaqI) alleles were found to be prevalent. 3 combinations of genotypes (TT/GG, TT/AG and CT/GG) were associated with the highest productivity (milk, protein and fat yields) among the breeds studied, as opposed to individuals carrying the worst CC/AA combination.

  2. study determined IGFR1 and PAPP-A (zeige PAPPA Proteine) expression both in follicles at different stages of development and in ovarian cysts; data indicate that animals with cystic ovarian disease (COD (zeige SNRPB Proteine)) have an altered regulation of the IGF system in the ovary and thus allow postulating IGFR1 expression and PAPP-A (zeige PAPPA Proteine) secretion as a modulator of IGF1 (zeige IGF1 Proteine) in cattle with COD (zeige SNRPB Proteine)

  3. Results of the present study showed, for the first time, that the polymorphism in IGF1R is associated with superovulation traits, and indicated that the IGFIR gene can be used as a potential marker for donor selection.

  4. two SNPs in the coding region of the insulin-like growth factor 1 receptor gene may have a role in growth of Angus cattle

  5. insulin (zeige INS Proteine)-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization

  6. The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain/HhaI, and UCP-3/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.

  7. Data describes the long-term changes to skeletal muscle growth and IGF1 (zeige IGF1 Proteine), 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine.

  8. Results do not support the premise that increased apoptosis associated with high levels of IGF1 (zeige IGF1 Proteine) is mediated via downregulation of the IGF1R as previously found in preimplantation mouse embryos.

  9. IGF-I (zeige IGF1 Proteine) down-regulated functional IGF-I receptor via GSK-3beta inhibition and mTOR (zeige FRAP1 Proteine) activation; constitutive activity of GSK-3beta maintained IGF-I receptor level in nonstimulated cells.

  10. IGF-1 (zeige IGF1 Proteine) and IGF-1r gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds.

Mouse (Murine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. These results support the role of Igf1r in controlling the kinetics of cell proliferation and differentiation during pulmonary airway epithelial regeneration after injury.

  2. Although smaller than WT (wild type) mice, old-aged Igf1r(+/-) had increased adiposity and exhibit increased lipogenesis. We hypothesize that IGF-1 (zeige IGF1 Proteine) resistance initially causes a transient increase in insulin (zeige INS Proteine) signaling thereby promoting a lipogenic phenotype, which subsequently leads to insulin (zeige INS Proteine) resistance.

  3. HASF is a novel ligand of IGF1R.

  4. Under nonpathological conditions, IGF-1 (zeige IGF1 Proteine) regulates brain IGF-1R. Because baseline IGF-1R levels are rapidly restored, a tight control of brain IGF-1R expression seems to operate under physiological conditions.

  5. These findings highlight the sex-dependent and potentially detrimental effects of in utero smoke exposure on DNA methylation (zeige HELLS Proteine) and Igf1 (zeige IGF1 Proteine) and Igf1r mRNA levels.

  6. MicroRNA-99a inhibits insulin (zeige INS Proteine)-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting IGF-1R and mTOR (zeige FRAP1 Proteine) signaling.

  7. These results indicated that IGF1R may increase cell viability under hypoxic conditions by promoting autophagy and scavenging reactive oxygen species production, which is closed with PI3K/Akt (zeige AKT1 Proteine)/mTOR (zeige FRAP1 Proteine) signaling pathway.

  8. When charged with hypoxia-ischemia, mutant brains with deleted IGF-1 (zeige IGF1 Proteine) receptor were broadly protected from cell damage, neuroinflammation and cerebral edema.

  9. Suggest that overexpression of IGF-IR or IRA (zeige INSR Proteine) isoform, as homodimers or as part of IRA (zeige INSR Proteine)/IGF-IR hybrid receptors, confers a stronger migratory capability to vascular smooth muscle cells and might occur in early stages of atherosclerotic process.

  10. Macrophage IGF1R signaling suppresses macrophage and foam cell accumulation in lesions and reduces plaque vulnerability, providing a novel mechanism whereby IGF-1 (zeige IGF1 Proteine) exerts antiatherogenic effects in ApoE (zeige APOE Proteine) knockout mice.

IGF1R Protein Überblick

Protein Überblick

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Alternative names and synonyms associated with IGF1R

  • insulin-like growth factor 1 receptor (IGF1R)
  • insulin-like growth factor 1 receptor (igf1r)
  • insulin-like growth factor 1 receptor (Igf1r)
  • insulin-like growth factor I receptor (Igf1r)
  • A330103N21Rik Protein
  • CD221 Protein
  • D930020L01 Protein
  • DKFZp469I0618 Protein
  • hyft Protein
  • IGF-1R Protein
  • IGF1R Protein
  • IGFIR Protein
  • IGFIRC Protein
  • IGFR Protein
  • IGFR1 Protein
  • JTK13 Protein
  • xIGF-1R Protein
  • xigf1r Protein
  • xIGFR Protein

Bezeichner auf Proteinebene für IGF1R

insulin-like growth factor 1 receptor , IGF-I receptor , insulin-like growth factor I receptor , soluble IGF1R variant 1 , soluble IGF1R variant 2 , insulin-like growth factor-1 receptor beta subunit , xIGF-1R , xIGFR , insulin-like growth factor receptor tyrosine kinase , insulin-like growth factor-I receptor , type 1 IGF receptor , tyrosine kinase , IGF-1 receptor , insulin-like growth factor 1 receptor beta subunit , insulin-like growth factor receptor 1 , insulin-like growth factor-1 receptor , receptor tyrosine kinase , line 186

GENE ID SPEZIES
100055698 Equus caballus
453676 Pan troglodytes
100172156 Pongo abelii
100329112 Xenopus (Silurana) tropicalis
100020095 Monodelphis domestica
3480 Homo sapiens
25718 Rattus norvegicus
398022 Xenopus laevis
395889 Gallus gallus
397350 Sus scrofa
281848 Bos taurus
442951 Canis lupus familiaris
100734840 Cavia porcellus
16001 Mus musculus
Ausgewählte Anbieter für IGF1R Proteine (IGF1R)
Haben Sie etwas anderes gesucht?