anti-IGF1R (IGF1R) Antikörper

Bezeichnung:
anti-Insulin-Like Growth Factor 1 Receptor Antikörper (IGF1R)
Auf www.antikoerper-online.de finden Sie aktuell 487 Insulin-Like Growth Factor 1 Receptor (IGF1R) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IGF1R Kits (53) und IGF1R Proteine (42) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 598 IGF1R Produkte verfügbar.
Synonyme:
A330103N21Rik, CD221, D930020L01, DKFZp469I0618, hyft, igf-1r, igf-ir, IGF1R, IGFIR, IGFIRC, IGFR, IGFR1, JTK13, xIGF-1R, xigf1r, xIGFR

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Am meisten referenzierte anti-IGF1R Antikörper

  1. Human Polyclonal IGF1R Primary Antibody für EIA, IHC (p) - ABIN359877 : Song, Barnes, Zhang, Bao, Kumar, Santen: The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Zeige alle 5 Referenzen für 359877

  2. Human Polyclonal IGF1R Primary Antibody für IHC (p), WB - ABIN391990 : Zhao, Dupont, Yakar, Karas, LeRoith: PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells. in Oncogene 2004 (PubMed)
    Zeige alle 5 Referenzen für 391990

  3. Human Monoclonal IGF1R Primary Antibody für Func, FACS - ABIN111141 : Hantel, Lewrick, Schneider, Zwermann, Perren, Reincke, Süss, Beuschlein: Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)
    Zeige alle 4 Referenzen für 111141

  4. Human Monoclonal IGF1R Primary Antibody für FACS, IHC (p) - ABIN181732 : Hantel, Lewrick, Reincke, Süss, Beuschlein: Liposomal doxorubicin-based treatment in a preclinical model of adrenocortical carcinoma. in The Journal of endocrinology 2012 (PubMed)
    Zeige alle 4 Referenzen für 181732

  5. Human Monoclonal IGF1R Primary Antibody für FACS - ABIN319437 : Li, Kato, Paz, Kasuya, Fujita-Yamaguchi: Two new monoclonal antibodies against the alpha subunit of the human insulin-like growth factor-I receptor. in Biochemical and biophysical research communications 1993 (PubMed)
    Zeige alle 3 Referenzen für 319437

  6. Human Polyclonal IGF1R Primary Antibody für FACS, IF - ABIN652374 : Lu, Zi, Zhao, Pollak: Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells. in Biochemical and biophysical research communications 2003 (PubMed)
    Zeige alle 3 Referenzen für 652374

  7. Human Polyclonal IGF1R Primary Antibody für IF (p), IHC (p) - ABIN802203 : Tang, Liao, Xu, Zhang, Liu, Deng, Jiang, Fu, Chen, Zhou: Estrogen and insulin-like growth factor 1 synergistically promote the development of lung adenocarcinoma in mice. in International journal of cancer. Journal international du cancer 2013 (PubMed)
    Zeige alle 2 Referenzen für 802203

  8. Human Polyclonal IGF1R Primary Antibody für WB - ABIN616037 : Adams, Epa, Garrett, Ward: Structure and function of the type 1 insulin-like growth factor receptor. in Cellular and molecular life sciences : CMLS 2000 (PubMed)
    Zeige alle 2 Referenzen für 616037

  9. Cow (Bovine) Polyclonal IGF1R Primary Antibody für IF, IHC - ABIN2792087 : Urano, Narusawa, Shiraki, Usui, Sasaki, Hosoi, Ouchi, Nakamura, Inoue: Association of a single nucleotide polymorphism in the insulin-like growth factor-1 receptor gene with spinal disc degeneration in postmenopausal Japanese women. in Spine 2008 (PubMed)
    Zeige alle 2 Referenzen für 2792087

  10. Human Polyclonal IGF1R Primary Antibody für FACS, IF (p) - ABIN726575 : Hu, Li, Hu, Wu, Li, Meng: MicroRNA let-7a and let-7f as novel regulatory factors of the sika deer (Cervus nippon) IGF-1R gene. in Growth factors (Chur, Switzerland) 2014 (PubMed)
    Zeige alle 2 Referenzen für 726575

Weitere Antikörper gegen IGF1R Interaktionspartner

Horse (Equine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. This study evaluated the expression of IGF-1 (zeige IGF1 Antikörper) receptor, insulin receptor (zeige INSR Antikörper) AND IGF-1 (zeige IGF1 Antikörper) in the lammelar tissue of horses with insulin (zeige INS Antikörper)-induced hyperinsulinemia.

  2. The laminar cell types expressing insulin receptor (zeige INSR Antikörper) and/or insulin-like growth factor-1 receptor and the effect of dietary carbohydrates on their expression are reported.

  3. Somatomedin (IGF-I (zeige IGF1 Antikörper)) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor is present in spermatogonia, spermatocytes and Leydig cells.[IGF-I receptor]

Human Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. We found that the thyroid hormone receptor (zeige THRA Antikörper) (TRalpha (zeige THRA Antikörper) 3) has a differential expression profile. Thyroid hormone (zeige PTH Antikörper) is critical for normal brain development. Our results showed that there is a possible link between IGF1 (zeige IGF1 Antikörper)/IGF1R and the TRalpha (zeige THRA Antikörper) 3 and that over expression of IGF1R in RTT cells may be the cause of neurites improvement in neural RTT-derived neurons.

  2. Data show that the let-7c/miR (zeige MLXIP Antikörper)-99a/miR (zeige MLXIP Antikörper)-125b cluster controlled tumorigenesis by targeting IL-6 (zeige IL6 Antikörper), IL-6R and IGF1R.

  3. IGF1R expression may have prognostic relevance in penile squamous cell carcinoma

  4. High IGF1R expression is associated with bone metastasis in prostate cancer.

  5. the Runx2 (zeige RUNX2 Antikörper) knockdown cells displayed activation of AMP-activated protein kinase (AMPKalpha (zeige GRK4 Antikörper)), the sensor of cellular metabolism. Importantly, the Runx2 (zeige RUNX2 Antikörper) knockdown in bone-derived cells resulted in increased sensitivity to both Erk1/2 (zeige MAPK1/3 Antikörper) inhibition and AMPKalpha (zeige GRK4 Antikörper) activation by PD184161 and metformin, respectively, despite increased IGF-1Rbeta and AMPKalpha (zeige GRK4 Antikörper) levels.

  6. Overexpression of mutated K-RAS in gastrointestinal cancer cell lines led to more aggressive phenotypes, with increased proliferation, decreased apoptosis, and increased motility and invasion. IGF-1R blockade suppressed cell growth, colony formation, migration, and invasion, and up-regulated chemotherapy-induced apoptosis of gastrointestinal cancer cells, even when mutated K-RAS was over-expressed.

  7. IFITM2 (zeige IFITM2 Antikörper) promotes gastric cancer growth and metastasis via IGF1 (zeige IGF1 Antikörper)/IGF1R/STAT3 (zeige STAT3 Antikörper) signaling pathway.

  8. The authors found low levels of IGF1R expression and PTEN (zeige PTEN Antikörper)-negative status to correlate with resistance to IGF1R inhibition as a treatment for Human T-Cell Acute Lymphoblastic Leukemias.

  9. miR (zeige MLXIP Antikörper)-15b inhibits the progression of glioblastoma cells through targeting IGF1R, and miR (zeige MLXIP Antikörper)-15b can be recommended as a tumor suppressor in the progression of glioblastoma.

  10. our findings suggested that miR (zeige MLXIP Antikörper)-205 serves as a prognostic factor and suppresses proliferation and invasion by targeting insulin (zeige INS Antikörper)-like growth factor receptor (zeige RYK Antikörper) 1 in human cervical cancer. Thus, miR (zeige MLXIP Antikörper)-205/insulin (zeige INS Antikörper)-like growth factor receptor (zeige RYK Antikörper) 1 pathway may be of great benefit to cervical cancer patients

Pig (Porcine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. IGF-I (zeige IGF1 Antikörper), IGF-II, and IGFBP-3 (zeige IGFBP3 Antikörper) mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.

  2. IL-1beta (zeige IL1B Antikörper) impaired the actions of IGF-I (zeige IGF1 Antikörper) at a point distal to the IGF receptor

  3. IGF-1R is expressed in porcine somatostatin (zeige SST Antikörper)-containing islet D-cells

  4. This study suggests an association between the affinity of insulin (zeige INS Antikörper) receptors and number of IGF-1 (zeige IGF1 Antikörper) receptors with placental and/or fetal growth.

  5. mRNA expression of IGF-I receptor

Cow (Bovine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. A total of 1169 cows of 4 pure breeds (Polish Holstein Friesian, Montbeliarde, Jersey and Holstein Friesian) were genotyped. The T (IGF1R/e2/MspI) and G (IGF1R/e2/TaqI) alleles were found to be prevalent. 3 combinations of genotypes (TT/GG, TT/AG and CT/GG) were associated with the highest productivity (milk, protein and fat yields) among the breeds studied, as opposed to individuals carrying the worst CC/AA combination.

  2. study determined IGFR1 and PAPP-A (zeige PAPPA Antikörper) expression both in follicles at different stages of development and in ovarian cysts; data indicate that animals with cystic ovarian disease (COD (zeige SNRPB Antikörper)) have an altered regulation of the IGF system in the ovary and thus allow postulating IGFR1 expression and PAPP-A (zeige PAPPA Antikörper) secretion as a modulator of IGF1 (zeige IGF1 Antikörper) in cattle with COD (zeige SNRPB Antikörper)

  3. Results of the present study showed, for the first time, that the polymorphism in IGF1R is associated with superovulation traits, and indicated that the IGFIR gene can be used as a potential marker for donor selection.

  4. two SNPs in the coding region of the insulin-like growth factor 1 receptor gene may have a role in growth of Angus cattle

  5. insulin (zeige INS Antikörper)-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization

  6. The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain (zeige CAPN2 Antikörper)/HhaI, and UCP-3 (zeige UCP3 Antikörper)/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.

  7. Data describes the long-term changes to skeletal muscle growth and IGF1 (zeige IGF1 Antikörper), 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine.

  8. Results do not support the premise that increased apoptosis associated with high levels of IGF1 (zeige IGF1 Antikörper) is mediated via downregulation of the IGF1R as previously found in preimplantation mouse embryos.

  9. IGF-I (zeige IGF1 Antikörper) down-regulated functional IGF-I receptor via GSK-3beta (zeige GSK3b Antikörper) inhibition and mTOR (zeige FRAP1 Antikörper) activation; constitutive activity of GSK-3beta (zeige GSK3b Antikörper) maintained IGF-I receptor level in nonstimulated cells.

  10. IGF-1 (zeige IGF1 Antikörper) and IGF-1r gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds.

Mouse (Murine) Insulin-Like Growth Factor 1 Receptor (IGF1R) Interaktionspartner

  1. SUMOylation of IGF1R affects upstream mechanisms that control and coordinate expression of cell cycle regulators to increase cell cycle progression and proliferation.

  2. findings demonstrated that significant resistance of the brain to amyloid-beta can be achieved lifelong by suppressing neuronal IGF1R.

  3. Results found that glioblastoma tumors resistant to PDGFR (zeige PDGFRB Antikörper) inhibition required the expression and activation of the insulin receptor (IR (zeige INSR Antikörper))/insulin (zeige INS Antikörper) growth-like factor receptor (IGF1R) for tumor cell proliferation and survival.

  4. Conditional deletion of synaptotagmin-10 (zeige SYT10 Antikörper), the Ca(2 (zeige CA2 Antikörper)+) sensor for IGF1 (zeige IGF1 Antikörper) secretion from mitral cells, or deletion of IGF1 (zeige IGF1 Antikörper) receptor in the olfactory bulb prevented the socially relevant GABAergic long-term potentiation and impaired memory formation after social transmission of food preference.

  5. These results support the role of Igf1r in controlling the kinetics of cell proliferation and differentiation during pulmonary airway epithelial regeneration after injury.

  6. Although smaller than WT (wild type) mice, old-aged Igf1r(+/-) had increased adiposity and exhibit increased lipogenesis. We hypothesize that IGF-1 (zeige IGF1 Antikörper) resistance initially causes a transient increase in insulin (zeige INS Antikörper) signaling thereby promoting a lipogenic phenotype, which subsequently leads to insulin (zeige INS Antikörper) resistance.

  7. HASF is a novel ligand of IGF1R.

  8. Under nonpathological conditions, IGF-1 (zeige IGF1 Antikörper) regulates brain IGF-1R. Because baseline IGF-1R levels are rapidly restored, a tight control of brain IGF-1R expression seems to operate under physiological conditions.

  9. These findings highlight the sex-dependent and potentially detrimental effects of in utero smoke exposure on DNA methylation (zeige HELLS Antikörper) and Igf1 (zeige IGF1 Antikörper) and Igf1r mRNA levels.

  10. MicroRNA-99a inhibits insulin (zeige INS Antikörper)-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting IGF-1R and mTOR (zeige FRAP1 Antikörper) signaling.

IGF1R Antigen-Profil

Beschreibung des Gens

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Alternative names and synonyms associated with IGF1R

  • insulin-like growth factor 1 receptor (IGF1R) Antikörper
  • insulin-like growth factor 1 receptor (Igf1r) Antikörper
  • insulin-like growth factor 1 receptor (igf1r) Antikörper
  • insulin-like growth factor I receptor (Igf1r) Antikörper
  • insulin-like growth factor I receptor (LOC780503) Antikörper
  • insulin-like growth factor I receptor (igf-ir) Antikörper
  • A330103N21Rik Antikörper
  • CD221 Antikörper
  • D930020L01 Antikörper
  • DKFZp469I0618 Antikörper
  • hyft Antikörper
  • igf-1r Antikörper
  • igf-ir Antikörper
  • IGF1R Antikörper
  • IGFIR Antikörper
  • IGFIRC Antikörper
  • IGFR Antikörper
  • IGFR1 Antikörper
  • JTK13 Antikörper
  • xIGF-1R Antikörper
  • xigf1r Antikörper
  • xIGFR Antikörper

Bezeichner auf Proteinebene für IGF1R

IGF-I receptor , insulin-like growth factor I receptor , soluble IGF1R variant 1 , soluble IGF1R variant 2 , insulin-like growth factor receptor tyrosine kinase , insulin-like growth factor-I receptor , type 1 IGF receptor , tyrosine kinase , IGF-1 receptor , insulin-like growth factor 1 receptor beta subunit , insulin-like growth factor receptor 1 , insulin-like growth factor-1 receptor , receptor tyrosine kinase , insulin-like growth factor 1 receptor , line 186 , insulin-like growth factor-1 receptor beta subunit , xIGF-1R , xIGFR

GENE ID SPEZIES
3480 Homo sapiens
25718 Rattus norvegicus
281848 Bos taurus
395889 Gallus gallus
397350 Sus scrofa
442951 Canis lupus familiaris
453676 Pan troglodytes
100172156 Pongo abelii
100329112 Xenopus (Silurana) tropicalis
16001 Mus musculus
100020095 Monodelphis domestica
780503 Ovis aries
100136427 Salmo salar
398022 Xenopus laevis
100055698 Equus caballus
100734840 Cavia porcellus
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