SFRS Protein Kinase 2 Proteine (SRPK2)

SFRS Protein Kinase 2 Proteine (SRPK2)
Auf finden Sie aktuell 19 SFRS Protein Kinase 2 (SRPK2) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SFRS Protein Kinase 2 Antikörper (45) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 67 SFRS Protein Kinase 2 Produkte verfügbar.
AW226533, AW492537, AW547358, MGC147832, mSRPK2, SFRSK2, srpk2, Wbp6
alle Proteine anzeigen Gen GeneID UniProt
SRPK2 20817 O54781
SRPK2 6733 P78362
Ratte SRPK2 SRPK2 296753  

Weitere Synonyme anzeigen

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Weitere Proteine zu SFRS Protein Kinase 2 Interaktionspartnern

Mouse (Murine) SFRS Protein Kinase 2 (SRPK2) Interaktionspartner

  1. SRPK2 may contribute to the formation of hyperphosphorylated tau and the pathogenesis of Alzheimer disease.

  2. Interaction of Akt (zeige AKT1 Proteine)-phosphorylated SRPK2 with 14-3-3 (zeige YWHAQ Proteine) mediates cell cycle and cell death in neurons.

Human SFRS Protein Kinase 2 (SRPK2) Interaktionspartner

  1. Delta-secretase phosphorylation by SRPK2 plays a critical role in aggravating Alzheimer disease pathogenesis.

  2. In this study, it was found that the expression of SRPK2 was up-regulated in the clinical colon cancer samples. Overexpression of SRPK2 promoted the growth and migration of colon cancer cells, while knocking down the expression of SRPK2 inhibited the growth, migration and tumorigenecity of colon cancer cells.

  3. Our results indicate that phosphorylation of SRPK2 plays a crucial role in the regulation of splicing process in head and neck squamous cell carcinoma (HNSCC), and that splicing kinases can be developed as a new class of therapeutic target in HNSCC.

  4. Data indicate serine/arginine-rich protein (zeige MANF Proteine) kinases SRPK1 (zeige SRPK1 Proteine)/2/SRPIN340 complexes by molecular docking and molecular dynamics.

  5. A conserved electronegative docking groove in SRPK2 is responsible for substrate binding.

  6. the BLRF2 RS motif is phosphorylated by SRPK2 and is important for viral replication.

  7. Our results demonstrate that SRPK1 (zeige SRPK1 Proteine) and SRPK2 are host factors essential for Hepatitis C virus replication.

  8. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: SRPK2.

  9. Both SRPK1 and SRPK2 are most likely the cellular protein kinases mediating HBV core protein phosphorylation during viral infection and therefore represent important host cell targets for therapeutic intervention in HBV infection.

  10. negative role of SRPK1 and SRPK2 in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein

SFRS Protein Kinase 2 (SRPK2) Protein Überblick

Protein Überblick

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up- regulation. Plays an essential role in splicesomal B complex formation via the phosphorylation of DDX23/PRP28.

Alternative names and synonyms associated with SFRS Protein Kinase 2 (SRPK2)

  • SFRS protein kinase 2 (SRPK2)
  • SFRS protein kinase 2 (srpk2)
  • SFRS protein kinase 3 (srpk3)
  • serine/arginine-rich protein specific kinase 2 (Srpk2)
  • SRSF protein kinase 2 (SRPK2)
  • SRSF protein kinase 2 (Srpk2)
  • AW226533 Protein
  • AW492537 Protein
  • AW547358 Protein
  • MGC147832 Protein
  • mSRPK2 Protein
  • SFRSK2 Protein
  • srpk2 Protein
  • Wbp6 Protein

Bezeichner auf Proteinebene für SFRS Protein Kinase 2 Proteine (SRPK2)

SFRS protein kinase 2 , SFRS protein kinase 3 , serine/threonine-protein kinase SRPK2-like , SR-protein-specific kinase 2 , SRSF protein kinase 2 , WW domain binding protein 6 , serine/arginine-rich protein-specific kinase 2 , serine/threonine-protein kinase SRPK2 , SR protein kinase 2 , serine kinase SRPK2 , serine/arginine-rich splicing factor kinase 2 , serine/arginine-rich protein specific kinase 2

463641 Pan troglodytes
100050379 Equus caballus
100124819 Xenopus (Silurana) tropicalis
100125041 Xenopus (Silurana) tropicalis
100390282 Callithrix jacchus
20817 Mus musculus
6733 Homo sapiens
296753 Rattus norvegicus
475894 Canis lupus familiaris
417711 Gallus gallus
505945 Bos taurus
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