anti-Kinesin Light Chain 1 (KLC1) Antikörper

Bezeichnung:
anti-Kinesin Light Chain 1 Antikörper (KLC1)
Auf www.antikoerper-online.de finden Sie aktuell 67 Kinesin Light Chain 1 (KLC1) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Kinesin Light Chain 1 Proteine (3) und Kinesin Light Chain 1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 76 Kinesin Light Chain 1 Produkte verfügbar.
Synonyme:
AI874768, kinesin-II, KLC, klc1, Klc2, KNS2, KNS2A, wu:fj17e04, zgc:55666, zgc:66299, zgc:77660

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Am meisten referenzierte anti-Kinesin Light Chain 1 Antikörper

  1. Human Polyclonal KLC1 Primary Antibody für FACS, IHC (p) - ABIN652577 : Chernajovsky, Brown, Clark: Human kinesin light (beta) chain gene: DNA sequence and functional characterization of its promoter and first exon. in DNA and cell biology 1997 (PubMed)
    Zeige alle 2 Referenzen für 652577

Weitere Antikörper gegen Kinesin Light Chain 1 Interaktionspartner

Human Kinesin Light Chain 1 (KLC1) Interaktionspartner

  1. All binary complexes (KLC1:APP (zeige APP Antikörper), KLC1:JIP1 (zeige MAPK8IP1 Antikörper), and APP:JIP1) contain conformations with favorable binding free energies indicating that KLC1 and JIP1 (zeige MAPK8IP1 Antikörper) may take part in APP (zeige APP Antikörper) transport in Alzheimer's disease patients.

  2. BNIP-2 (zeige BNIP2 Antikörper) is a kinesin-1 adapter involved in vesicular transportation in the cytoplasm and that association with cargos depends on interaction of the CRAL-TRIO (zeige TRIO Antikörper) domain with membrane phosphatidylserine.

  3. The G allele and GG genotype of KLC1 rs8702 were significantly over-represented among cataract patients, as compared to healthy controls, and were associated with an odds ratio for cataract development.

  4. Dnm1L (zeige DNM1L Antikörper) interacts with KLC1 through the tetratricopeptide repeat domains.

  5. Microtubule-bound kinesin-1 and kinesin-3 motor domains were visualized at multiple steps in their ATPase (zeige DNAH8 Antikörper) cycles--including their nucleotide-free states--at approximately 7 A resolution using cryo-electron microscopy.

  6. Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1 (zeige LZTS1 Antikörper)), SCOCO (short coiled-coil protein (zeige SCOC Antikörper)) and kinesins (kinesin heavy chain (zeige KIF5A Antikörper)) are involved in biological transport process.

  7. The expression levels of KLC1 variant E in brain and lymphocytes were significantly higher in Alzheimer's disease patients.

  8. study provides evidence that the combined effect of three variants within the KLC1 gene may predispose to age-related cataract.

  9. For the binding of cargos shared by KLC1, we propose a different site located within the groove but not involving N343.

  10. Data suggest that KLC1 is required for normal neural differentiation, ensuring proper metabolism of AD-associated molecules APP (zeige APP Antikörper) and Tau and for proliferation of neural precursors (NPs (zeige NPS Antikörper)).

Mouse (Murine) Kinesin Light Chain 1 (KLC1) Interaktionspartner

  1. In old mice, lack of KLC1 results in retinal pigment epithelium pathogenesis that was strikingly comparable to aspects of age-related macular degeneration.

  2. Alcalpha (zeige CLSTN1 Antikörper) is efficiently processed in part to minimize the inappropriate peripheral retention of kinesin-1

  3. A small peptide sequence is sufficient for initiating kinesin-1 activation through part of TPR (zeige GRID2 Antikörper) region of KLC1

  4. Data show that amyloid precursor protein (APP (zeige APP Antikörper)) levels are well-correlated with the amount of the light chain of kinesin-1 (KLC1).

  5. KLC1-ALK (zeige ALK Antikörper) is the first novel oncogenic fusion identified using only formalin-fixed paraffin-embedded tissue tissues

  6. Phosphorylation of KLC1 at serine 460 modulates binding and trafficking of calsyntenin-1 (zeige CLSTN1 Antikörper).

  7. changes in the phosphorylation state of KLC1 at Ser517/520 are unlikely to affect motor function.

  8. An essential role of mNUDC for anterograde transport of dynein and dynactin (zeige DCTN1 Antikörper) by kinesin-1.

  9. Impairment of anterograde transport by knockdown of KIF5B (zeige KIF5B Antikörper) or KLC1 delayed stress-granule dissolution.

  10. analysis of a novel protein-protein interaction between KLC1 and JLP that involves leucine zipper-like domains

Kinesin Light Chain 1 (KLC1) Antigen-Profil

Beschreibung des Gens

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos\; however, the full-length nature and/or biological validity of most of these variants have not been determined.

Alternative names and synonyms associated with Kinesin Light Chain 1 (KLC1)

  • kinesin light chain 1b (klc1b) Antikörper
  • kinesin light chain 1 (KLC1) Antikörper
  • kinesin light chain 1a (klc1a) Antikörper
  • kinesin light chain 1 (klc1) Antikörper
  • kinesin light chain 1 (Klc1) Antikörper
  • AI874768 Antikörper
  • kinesin-II Antikörper
  • KLC Antikörper
  • klc1 Antikörper
  • Klc2 Antikörper
  • KNS2 Antikörper
  • KNS2A Antikörper
  • wu:fj17e04 Antikörper
  • zgc:55666 Antikörper
  • zgc:66299 Antikörper
  • zgc:77660 Antikörper

Bezeichner auf Proteinebene für KLC1

kinesin 2 , kinesin light chain 1 , kinesin light chain 2 , kinesin light chain 4 , kinesin 2 60/70kDa , kinesin ii , KLC 1 , medulloblastoma antigen MU-MB-2.50

GENE ID SPEZIES
335499 Danio rerio
508999 Bos taurus
393928 Danio rerio
550001 Xenopus (Silurana) tropicalis
100016881 Monodelphis domestica
100075996 Ornithorhynchus anatinus
100380464 Salmo salar
100560020 Anolis carolinensis
3831 Homo sapiens
171041 Rattus norvegicus
16593 Mus musculus
423484 Gallus gallus
100173833 Pongo abelii
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